Phenotype: abnormal KLRG1+ CD8 alpha-beta T cell number

Definition
anomaly in the number of CD8+ alpha beta T cells that express KLRG1, a marker of effector and memory T cells
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal KLRG1+ CD8 alpha-beta T cell number

Total number of significant genotype-phenotype associations: 7

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD8+
Spleen Immunophenotyping
WTSI
3i
0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD8+
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Gmds
Gmdstm1a(KOMP)Wtsi
HOM   Early adult decreased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM   Early adult increased KLRG1+ CD8 alpha-beta T cell number KLRG1+ CD8+ T cells - % of CD45+
Mesenteric Lymph Node Immunophenotyping
WTSI
3i
0.00

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

1.06% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal KLRG1+ CD8 alpha-beta T cell number (5/473)

16.67% females (1/6) 16.67% males (1/6)

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