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Phenotype: decreased Ly6C high monocyte number

Definition
decrease in the number of monocytes that express high levels of Ly6C and low MHC class II that represent a subset of circulating inflammatory monocytes that are recruited to infected or inflamed tissues
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased Ly6C high monocyte number

Total number of significant genotype-phenotype associations: 2

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Tmem127
Tmem127tm1(KOMP)Wtsi 		HOM Early adult decreased Ly6C high monocyte number Ly6Chigh monocyte number
Whole blood peripheral blood leukocyte immunophenotyping		 WTSI
3i		 0.00

Download data as:   TSV   XLS

 The way we measure

Procedure
Whole blood peripheral blood leukocyte immunophenotyping

 Phenotype associations stats

0.22% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased Ly6C high monocyte number (1/450)

14.29% females (1/7) 100.00% males (1/1)

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