Phenotype: enhanced conditioning behavior

Definition
enhanced ability to change behavior in response to a reward or punishment each time an action is performed
Synonyms
increased conditioning behavior,  enhanced conditioning behaviour
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with enhanced conditioning behavior

Total number of significant genotype-phenotype associations: 26

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Plaat5
Plaat5em1(IMPC)Tcp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
TCP
IMPC
3.00×10-12
Ubqln4
Ubqln4em1(IMPC)Mbp
HOM Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
4.81×10-12
Ms4a4a
Ms4a4aem1(IMPC)Mbp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
2.50×10-08
Sox2
Sox2em1(IMPC)Mbp
HET Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
3.00×10-08
Tasor
Tasorem1(IMPC)Ccpcz
HET Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
6.25×10-08
Pald1
Pald1em1(IMPC)Kmpc
HOM Late adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
KMPC
IMPC
4.73×10-07
Dele1
Dele1em2(IMPC)Ccpcz
HOM   Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
7.43×10-07
St6gal2
St6gal2em1(IMPC)H
HOM Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
MRC Harwell
IMPC
1.94×10-06
Irag1
Irag1em1(IMPC)Ccpcz
HOM   Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
2.75×10-06
Sla2
Sla2em1(IMPC)Ccpcz
HOM   Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
4.13×10-06
Cartpt
Cartptem1(IMPC)Mbp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
6.06×10-06
Tent5a
Tent5aem1(IMPC)Ccpcz
HOM Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
7.69×10-06
Ubqln4
Ubqln4em1(IMPC)Mbp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
2.64×10-05
Nufip1
Nufip1em1(IMPC)Mbp
HET Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
2.65×10-05
Kcnt2
Kcnt2em1(IMPC)Mbp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
3.51×10-05
Tmtc2
Tmtc2em2(IMPC)Kmpc
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
KMPC
IMPC
3.85×10-05
Tmem132e
Tmem132eem1(IMPC)Kmpc
HET Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
KMPC
IMPC
3.88×10-05
Irag1
Irag1em1(IMPC)Ccpcz
HOM   Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
5.00×10-05
Serac1
Serac1em1(IMPC)Tcp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
TCP
IMPC
6.56×10-05
Nsg2
Nsg2em1(IMPC)Kmpc
HOM Early adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
KMPC
IMPC
8.11×10-05
Wdr27
Wdr27em1(IMPC)Ccpcz
HOM   Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
8.45×10-05
Emd
Emdem1(IMPC)Kmpc
HOM Late adult enhanced cued conditioning behavior Difference in Cue Tone and Cue Baseline % Freezing
Fear Conditioning
KMPC
IMPC
8.86×10-05
Cacna2d1
Cacna2d1em1(IMPC)Mbp
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
9.33×10-05
Marchf3
Marchf3tm1b(EUCOMM)Hmgu
HOM Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
CCP-IMG
IMPC
9.50×10-05
Tmem225
Tmem225em1(IMPC)Mbp
HOM   Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
UC Davis
IMPC
9.93×10-05
Cyp21a1
Cyp21a1em1(IMPC)Tcp
HET Early adult enhanced contextual conditioning behavior Difference in Context and Conditioning Baseline % Freezing
Fear Conditioning
TCP
IMPC
9.96×10-05

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 The way we measure

Procedure
Fear Conditioning

 Phenotype associations stats

1.52% of tested genes with null mutations on a B6N genetic background have a phenotype association to enhanced conditioning behavior (24/1582)

0.55% females (8/1452) 0.70% males (11/1579)

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