Phenotype: prolonged PQ interval

Definition
increase in the length of time between the beginning of atrial depolarization and the end of atrial repolarization (or recovery), measured by the interval from the beginning of the P wave to the end of the Q wave
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with prolonged PQ interval

Total number of significant genotype-phenotype associations: 8

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Grtp1
Grtp1tm1b(EUCOMM)Hmgu
HOM   Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ TCP | IMPC 6.76×10-06
Rnf10
Rnf10em1(IMPC)J
HOM Late adult prolonged PQ interval Electrocardiogram (ECG) | PQ JAX | IMPC 1.56×10-05
Glp1r
Glp1rtm1b(KOMP)Mbp
HOM Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ MRC Harwell | IMPC 2.49×10-05
Pbx3
Pbx3tm1b(EUCOMM)Wtsi
HET Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ MRC Harwell | IMPC 2.60×10-05
C1qtnf2
C1qtnf2tm2b(KOMP)Wtsi
HOM Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ MRC Harwell | IMPC 4.80×10-05
Klhdc2
Klhdc2tm1b(EUCOMM)Hmgu
HET Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ MRC Harwell | IMPC 5.27×10-05
Usp22
Usp22tm1b(KOMP)Wtsi
HET Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ MRC Harwell | IMPC 5.38×10-05
Gdf15
Gdf15tm1b(KOMP)Wtsi
HOM   Early adult prolonged PQ interval Electrocardiogram (ECG) | PQ MRC Harwell | IMPC 9.96×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.32% of tested genes with null mutations on a B6N genetic background have a phenotype association to prolonged PQ interval (8/2504)

0.20% females (5/2459) 0.04% males (1/2454)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter