Definition
any anomaly in the concentration of the fatty acids which occur in plasma as a result of lipolysis in adipose tissue or when plasma triacyglycerols are taken into tissues
Synonyms
abnormal non-esterified fatty acids level,
abnormal FFA level,
abnormal free fatty acid level
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal free fatty acids level
Total number of significant genotype-phenotype associations: 87
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Lgals7 Lgals7tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.49×10-09 | |
| Col18a1 Col18a1tm1.1(KOMP)Vlcg |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
1.58×10-09 | |
| Ccdc18 Ccdc18tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.85×10-09 | |
| Mindy1 Mindy1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
6.04×10-09 | |
| Ccdc120 Ccdc120tm1.1(KOMP)Vlcg |
HEM | Early adult | increased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
1.08×10-08 | |
| Cenpo Cenpotm1b(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.15×10-08 | |
| Ap2a2 Ap2a2tm1b(EUCOMM)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.14×10-07 | |
| Diaph3 Diaph3tm1b(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
2.14×10-07 | |
| Rint1 Rint1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.48×10-07 | |
| Cc2d1b Cc2d1btm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
3.70×10-07 | |
| Dap Daptm1a(KOMP)Mbp |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
4.17×10-07 | |
| Ap4e1 Ap4e1em1(IMPC)J |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
6.42×10-07 | |
| Lonrf3 Lonrf3tm1a(KOMP)Wtsi |
HEM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
6.57×10-07 | |
| Plcg2 Plcg2Ali14 |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
HMGU EuroPhenome |
7.50×10-07 | |
| Ap4e1 Ap4e1em1(IMPC)J |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
8.11×10-07 | |
| Ift25 Ift25tm1a(EUCOMM)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
WTSI EuroPhenome |
9.08×10-07 | |
| Cc2d1b Cc2d1btm1a(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
9.20×10-07 | |
| Dbn1 Dbn1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
1.10×10-06 | |
| Kif26b Kif26btm2b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
1.35×10-06 | |
| Cpgi15344 Cpgi15344tm1.1(NCC)WCS |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.41×10-06 | |
| Sdha Sdhatm2b(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
1.42×10-06 | |
| Tbc1d22a Tbc1d22atm1b(KOMP)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.54×10-06 | |
| Arrb2 Arrb2tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
2.22×10-06 | |
| Cyb5d1 Cyb5d1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.33×10-06 | |
| Syce1l Syce1ltm1.1(KOMP)Vlcg |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.40×10-06 | |
| Zfp637 Zfp637em1(IMPC)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
3.56×10-06 | |
| Rpa1 Rpa1tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.69×10-06 | |
| Arhgef4 Arhgef4tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
3.94×10-06 | |
| Snf8 Snf8tm1a(EUCOMM)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell MGP |
4.56×10-06 | |
| Dop1b Dop1btm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
4.81×10-06 | |
| Rc3h2 Rc3h2tm1a(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
HMGU EuroPhenome |
5.05×10-06 | |
| Bloc1s2 Bloc1s2tm1.1(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.23×10-06 | |
| Dpy19l3 Dpy19l3tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
ICS EuroPhenome |
5.71×10-06 | |
| Polr2h Polr2htm1.1(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
6.63×10-06 | |
| Chn1 Chn1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
6.66×10-06 | |
| Tpgs2 Tpgs2tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.77×10-06 | |
| Gm28050 Gm28050tm1.1(NCC)WCS |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
7.82×10-06 | |
| Fam110b Fam110btm1e(EUCOMM)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
HMGU EuroPhenome |
7.83×10-06 | |
| Hspb3 Hspb3tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.88×10-06 | |
| Mtarc2 Mtarc2tm2a(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
ICS EuroPhenome |
9.70×10-06 | |
| Hbs1l Hbs1ltm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.09×10-05 | |
| Mtrf1l Mtrf1ltm1a(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
1.23×10-05 | |
| Rhd Rhdtm1e(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI EuroPhenome |
1.31×10-05 | |
| Map3k1 Map3k1tm1a(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
1.52×10-05 | |
| Hmx3 Hmx3tm1Ebo |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
1.95×10-05 | |
| Resp18 Resp18tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
2.41×10-05 | |
| Gnasas1 Gnasas1tm2.1Jop |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell EuroPhenome |
2.44×10-05 | |
| Ska2 Ska2tm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
2.65×10-05 | |
| Arhgef4 Arhgef4tm1a(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
HMGU EuroPhenome |
2.65×10-05 | |
| Car7 Car7tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
2.81×10-05 | |
| Entpd1 Entpd1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell EuroPhenome |
2.94×10-05 | |
| Osm Osmtm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.20×10-05 | |
| Dnajc9 Dnajc9tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.32×10-05 | |
| Prep Preptm1b(KOMP)Wtsi |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
3.65×10-05 | |
| Msx1 Msx1tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
3.77×10-05 | |
| Krt7 Krt7tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
3.89×10-05 | |
| Cpgi5563 Cpgi5563tm1.1(NCC)WCS |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
4.70×10-05 | |
| Kcnh3 Kcnh3tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.06×10-05 | |
| Ceacam16 Ceacam16tm1.1(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.22×10-05 | |
| Nfkb1 Nfkb1tm1a(KOMP)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
WTSI EuroPhenome |
5.38×10-05 | |
| Irf8 Irf8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
5.40×10-05 | |
| Klc2 Klc2tm1e(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
5.91×10-05 | |
| Frrs1 Frrs1tm1a(EUCOMM)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
6.07×10-05 | |
| Trmt10a Trmt10atm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
6.11×10-05 | |
| Pycr1 Pycr1tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
6.13×10-05 | |
| Tigit Tigittm1.1(IMPC)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
6.58×10-05 | |
| Dhx30 Dhx30tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.18×10-05 | |
| Ppil3 Ppil3tm1b(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
7.38×10-05 | |
| Palb2 Palb2tm1.1(KOMP)Vlcg |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.40×10-05 | |
| Mmp8 Mmp8tm1.1(KOMP)Vlcg |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Plasma Chemistry |
JAX IMPC |
7.58×10-05 | |
| H1f10 H1f10tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
7.63×10-05 | |
| Smyd4 Smyd4tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
7.64×10-05 | |
| Rnf169 Rnf169tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
MRC Harwell EuroPhenome |
7.73×10-05 | |
| Cfh Cfhtm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
7.77×10-05 | |
| Ypel4 Ypel4tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
7.86×10-05 | |
| Mier1 Mier1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased circulating free fatty acids level | Free fatty acids Fasted Clinical Chemistry |
WTSI EuroPhenome |
8.25×10-05 | |
| Dctn4 Dctn4em1(IMPC)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
WTSI IMPC |
8.38×10-05 | |
| Rfc1 Rfc1tm1b(KOMP)Mbp |
HET | Early adult | decreased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
8.44×10-05 | |
| Zfp346 Zfp346tm1.1(KOMP)Vlcg |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
9.28×10-05 | |
| Itga8 Itga8tm1b(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acids Clinical Chemistry |
JAX IMPC |
9.56×10-05 | |
| Cog2 Cog2tm1a(KOMP)Wtsi |
HET | Early adult | increased circulating free fatty acids level | Free fatty acid Clinical Chemistry |
WTSI MGP |
9.85×10-05 |