Definition
any structural anomaly of the mature form of a B cell, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex
Synonyms
abnormal mature B lymphocyte morphology,
abnormal mature B-lymphocyte morphology,
abnormal mature B-cell morphology
0%
of tested genes
0
significant genes
0
tested genes
IMPC Gene variants with abnormal mature B cell morphology
Total number of significant genotype-phenotype associations: 35
| Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
|---|---|---|---|---|---|---|---|
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of B2 cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | increased early germinal center B cell number | Early germinal centre B cells - % of GC cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | increased germinal center B cell number | Germinal centre B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Aicda Aicdatm1b(EUCOMM)Hmgu |
HOM | Early adult | decreased late germinal center B cell number | Late germinal centre B cells - % of GC cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgap17 Arhgap17tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased B-1a cell number | B1a cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgap17 Arhgap17tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Arhgef1 Arhgef1tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased marginal zone B cell number | Marginal zone B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased B-2 B cell number | Total B2 cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | increased follicular B cell number | Follicular B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Cog6 Cog6tm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased marginal zone B cell number | Marginal zone B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Dph6 Dph6tm1a(KOMP)Wtsi |
HOM | Early adult | increased marginal zone B cell number | Marginal zone B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Duoxa2 Duoxa2tm1b(KOMP)Wtsi |
HOM | Early adult | decreased B-2 B cell number | Total B2 cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Gm5544 Gm5544tm1a(KOMP)Wtsi |
HET | Early adult | decreased marginal zone B cell number | Marginal zone B cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased early germinal center B cell number | Early germinal centre B cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | decreased germinal center B cell number | Germinal centre B cells - % of B2 cells Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Sik3 Sik3tm1a(EUCOMM)Hmgu |
HOM | Early adult | increased follicular B cell number | Follicular B cells - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | decreased B-2 B cell number | Total B2 cells - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
| Ydjc Ydjctm1(KOMP)Wtsi |
HOM | Early adult | increased germinal center B cell number | Germinal centre B cells - % of B2 cells Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased B-2 B cell number | B2B Cells Immunophenotyping |
HMGU IMPC |
2.22×10-11 | |
| Abcg8 Abcg8tm1b(KOMP)Wtsi |
HOM | Early adult | decreased B-2 B cell number | B2B Cells Immunophenotyping |
CCP-IMG IMPC |
9.67×10-11 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased follicular B cell number | Follicular B Cells (CD21/35+) Immunophenotyping |
HMGU IMPC |
1.68×10-10 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased marginal zone B cell number | MZB (CD21/35 high) Immunophenotyping |
HMGU IMPC |
9.79×10-08 | |
| Klrb1 Klrb1tm1b(EUCOMM)Wtsi |
HOM | Late adult | increased follicular B cell number | Follicular B Cells Immunophenotyping |
HMGU IMPC |
4.70×10-06 | |
| Pepd Pepdtm1b(KOMP)Wtsi |
HOM | Late adult | decreased follicular B cell number | Follicular B Cells (CD21/35+) Immunophenotyping |
HMGU IMPC |
1.07×10-05 | |
| Pepd Pepdtm1b(KOMP)Wtsi |
HOM | Late adult | decreased B-2 B cell number | B2B Cells Immunophenotyping |
HMGU IMPC |
1.91×10-05 | |
| Lratd2 Lratd2em1(IMPC)Ccpcz |
HOM | Early adult | increased B-2 B cell number | B2B Cells Immunophenotyping |
CCP-IMG IMPC |
2.00×10-05 | |
| Bach2 Bach2tm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased B-1a cell number | B1B Cells Immunophenotyping |
HMGU IMPC |
3.10×10-05 | |
| Timp2 Timp2em1(IMPC)Hmgu |
HOM | Late adult | increased follicular B cell number | Follicular B Cells Immunophenotyping |
HMGU IMPC |
3.56×10-05 | |
| Timp2 Timp2em1(IMPC)Hmgu |
HOM | Late adult | increased B-2 B cell number | B2B Cells Immunophenotyping |
HMGU IMPC |
7.20×10-05 | |
| Myoz1 Myoz1tm1b(EUCOMM)Hmgu |
HOM | Late adult | increased marginal zone B cell number | MZB (CD21/35 high) Immunophenotyping |
HMGU IMPC |
8.45×10-05 |