IMPC Gene variants with decreased plasmacytoid dendritic cell number
Total number of significant genotype-phenotype associations: 5
Gene / Allele | Zygosity | Sex | Life Stage | Phenotype | Parameter | Phenotyping Center |
P Value |
---|---|---|---|---|---|---|---|
Gmds Gmdstm1a(KOMP)Wtsi |
HOM | Early adult | decreased plasmacytoid dendritic cell number | Plasmacytoid DC - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Pclaf Pclaftm1a(EUCOMM)Wtsi |
HOM | Early adult | decreased plasmacytoid dendritic cell number | Plasmacytoid DC - % of CD45+ Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Tmem127 Tmem127tm1(KOMP)Wtsi |
HOM | Early adult | decreased plasmacytoid dendritic cell number | Plasmacytoid DC - % of CD45+ Spleen Immunophenotyping |
WTSI 3i |
0.00 | |
Vps13a Vps13atm1b(EUCOMM)Wtsi |
HOM | Early adult | decreased plasmacytoid dendritic cell number | Plasmacytoid DC - % of DC Mesenteric Lymph Node Immunophenotyping |
WTSI 3i |
0.00 | |
Tyk2 Tyk2tm2b(EUCOMM)Hmgu |
HOM | Late adult | decreased plasmacytoid dendritic cell number | pDCs Immunophenotyping |
HMGU IMPC |
2.53×10-05 |