Phenotype: decreased circulating cholesterol level

Definition
less than the normal amount in the blood of the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones; it is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues
Synonyms
hypocholesterolaemia,  decreased total circulating cholesterol level,  hypocholesterolemia,  reduced circulating cholesterol level,  low total circulating cholesterol level
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased circulating cholesterol level

Total number of significant genotype-phenotype associations: 329

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Slc29a3
Slc29a3em1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.22×10-43
Slc29a3
Slc29a3em1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.26×10-41
Pcsk9
Pcsk9tm2b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
6.61×10-25
Tnip1
Tnip1tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
IMPC
5.70×10-23
Apoc4
Apoc4tm1.1(KOMP)Mbp
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
2.20×10-21
Pcsk9
Pcsk9tm2b(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
4.06×10-21
Tnip1
Tnip1tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MRC Harwell
IMPC
9.93×10-20
Angptl3
Angptl3tm2b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
3.53×10-16
Cpgi5563
Cpgi5563tm1.1(NCC)WCS
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.57×10-15
Cpgi5563
Cpgi5563tm1.1(NCC)WCS
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
6.44×10-15
Slc29a3
Slc29a3em1(IMPC)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.45×10-14
Sec16b
Sec16btm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
2.54×10-14
Tex261
Tex261tm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.04×10-13
Plcg2
Plcg2Ali14
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
EuroPhenome
8.01×10-13
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
TCP
IMPC
2.74×10-12
Akap9
Akap9tm1a(KOMP)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
3.18×10-12
Akap9
Akap9tm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
4.08×10-12
Brd7
Brd7tm3a(EUCOMM)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Fasted Clinical Chemistry
WTSI
MGP
6.98×10-12
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
IMPC
8.46×10-12
Acsl5
Acsl5tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
8.90×10-12
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
9.34×10-12
Larp1
Larp1em1(IMPC)Mbp
HET Late adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
1.15×10-11
Angptl3
Angptl3tm2b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
1.52×10-11
Baat
Baatem1(IMPC)Mbp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
1.93×10-11
Tex261
Tex261tm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.45×10-11
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
7.20×10-11
Far2
Far2tm2b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
7.24×10-11
Akap9
Akap9tm1a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
1.82×10-10
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.90×10-10
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
EuroPhenome
2.41×10-10
Sec16b
Sec16btm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.93×10-10
Dcun1d3
Dcun1d3em1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.78×10-10
Dym
Dymem1(IMPC)Tcp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
TCP
IMPC
6.38×10-10
Hells
Hellstm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Fasted Clinical Chemistry
HMGU
EuroPhenome
6.67×10-10
Apoc4
Apoc4tm1.1(KOMP)Mbp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
1.03×10-09
Ube3b
Ube3bGt(RRJ142)Byg
HOM   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.55×10-09
Dcun1d3
Dcun1d3em1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
2.15×10-09
Nrxn1
Nrxn1tm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MRC Harwell
IMPC
2.23×10-09
Cenpo
Cenpotm1b(KOMP)Mbp
HET Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
2.37×10-09
Dbn1
Dbn1tm1b(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
BCM
IMPC
3.53×10-09
Ttc28
Ttc28tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
TCP
IMPC
4.39×10-09
Tmem203
Tmem203em1(IMPC)H
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
IMPC
5.75×10-09
Trpc3
Trpc3Mwk
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
EuroPhenome
5.95×10-09
Dusp7
Dusp7tm1(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MARC
IMPC
7.14×10-09
Sqstm1
Sqstm1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
7.21×10-09
Sec24a
Sec24atm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
7.77×10-09
Acsl5
Acsl5tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
UC Davis
IMPC
7.92×10-09
Tial1
Tial1tm1b(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
8.44×10-09
Sqstm1
Sqstm1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
9.43×10-09
Atad2b
Atad2btm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
1.05×10-08
Dll1
Dll1tm1Gos
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical chemistry (GMC)
HMGU
EuroPhenome
1.38×10-08
Setd1a
Setd1atm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.82×10-08
Ttll4
Ttll4tm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Fasted Clinical Chemistry
HMGU
EuroPhenome
1.91×10-08
BC048403
BC048403tm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MARC
IMPC
2.10×10-08
Ube3b
Ube3bGt(RRJ142)Byg
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
2.14×10-08
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
2.27×10-08
Sar1b
Sar1btm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.69×10-08
Setd1a
Setd1atm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
3.19×10-08
Zfp84
Zfp84tm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.19×10-08
Sar1b
Sar1btm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
3.74×10-08
Nsf
Nsftm1b(KOMP)Mbp
HET Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
4.65×10-08
Zfand6
Zfand6em1(IMPC)Mbp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
5.21×10-08
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
5.33×10-08
Sec24a
Sec24atm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
5.72×10-08
Etv6
Etv6em1(IMPC)Rbrc
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
RBRC
IMPC
5.76×10-08
Arhgap22
Arhgap22tm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
7.66×10-08
Prkab1
Prkab1tm1b(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
7.75×10-08
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
8.90×10-08
Dym
Dymem1(IMPC)Tcp
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
TCP
IMPC
9.06×10-08
Tial1
Tial1tm1b(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
9.18×10-08
Vangl2
Vangl2Lp
HET Early adult decreased circulating cholesterol level Total cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
1.26×10-07
Camsap3
Camsap3tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.30×10-07
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
1.38×10-07
Trim8
Trim8em1(IMPC)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.52×10-07
Far2
Far2tm2b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
1.67×10-07
Smc5
Smc5tm1b(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
1.67×10-07
Gc
Gctm1.1(KOMP)Vlcg
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
UC Davis
IMPC
1.70×10-07
Mta1
Mta1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Fasted Clinical Chemistry
WTSI
EuroPhenome
1.74×10-07
Pcdhb13
Pcdhb13em1(IMPC)Tcp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
TCP
IMPC
1.90×10-07
C1qtnf1
C1qtnf1em1(IMPC)Mbp
HOM Late adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
2.09×10-07
Setd1a
Setd1atm1a(EUCOMM)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.42×10-07
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
2.63×10-07
Nab2
Nab2tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
2.64×10-07
Bhlhe40
Bhlhe40tm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
2.81×10-07
Cpgi5563
Cpgi5563tm1.1(NCC)WCS
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
2.86×10-07
Nab2
Nab2tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
3.10×10-07
Ahrr
Ahrrtm1b(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
3.40×10-07
Tmem203
Tmem203em1(IMPC)H
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MRC Harwell
IMPC
3.47×10-07
Ywhab
Ywhabtm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
4.09×10-07
Dbn1
Dbn1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
4.11×10-07
Gda
Gdatm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
4.41×10-07
Ywhab
Ywhabtm1b(EUCOMM)Hmgu
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
4.65×10-07
Atad3a
Atad3atm1a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.11×10-07
Tmc6
Tmc6tm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
5.11×10-07
4933434E20Rik
4933434E20Riktm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.29×10-07
Fbf1
Fbf1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.90×10-07
Ube3b
Ube3bGt(RRJ142)Byg
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
6.41×10-07
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
EuroPhenome
6.60×10-07
Vil1
Vil1em1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
6.61×10-07
Sec16b
Sec16btm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
6.83×10-07
Sar1b
Sar1btm1a(EUCOMM)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
7.31×10-07
Cpgi15344
Cpgi15344tm1.1(NCC)WCS
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
7.41×10-07
Slc38a10
Slc38a10tm2a(EUCOMM)Wtsi
HET   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Fasted Clinical Chemistry
HMGU
EuroPhenome
7.62×10-07
Cracdl
Cracdltm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
8.92×10-07
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
1.03×10-06
Dnajc10
Dnajc10tm1a(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
1.08×10-06
Smc5
Smc5tm1b(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
1.09×10-06
Vil1
Vil1em1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.14×10-06
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
1.32×10-06
BC048403
BC048403tm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MARC
IMPC
1.32×10-06
Sqstm1
Sqstm1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.37×10-06
Fam117b
Fam117btm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
1.41×10-06
Il2ra
Il2ratm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
1.46×10-06
Slc16a2
Slc16a2tm1a(KOMP)Wtsi
HEM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
1.48×10-06
Fam117b
Fam117btm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
1.62×10-06
Cenpo
Cenpotm1b(KOMP)Mbp
HET Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
1.69×10-06
Septin8
Septin8tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
EuroPhenome
1.81×10-06
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
1.86×10-06
Vangl2
Vangl2Lp
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
1.89×10-06
Camsap3
Camsap3tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
2.12×10-06
Dusp7
Dusp7tm1(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MARC
IMPC
2.27×10-06
Xbp1
Xbp1tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
EuroPhenome
2.31×10-06
Sesn3
Sesn3tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.31×10-06
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.42×10-06
Rbpj
Rbpjtm1b(EUCOMM)Hmgu
HET   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
JAX
IMPC
2.46×10-06
Wrap53
Wrap53tm1b(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
2.58×10-06
Zfp84
Zfp84tm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
2.58×10-06
Gpr146
Gpr146em1(IMPC)H
HOM   Late adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MRC Harwell
IMPC
2.75×10-06
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
2.76×10-06
Gc
Gctm1.1(KOMP)Vlcg
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
2.85×10-06
Dusp26
Dusp26tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.86×10-06
Trim8
Trim8em1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.09×10-06
Ube2b
Ube2btm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
EuroPhenome
3.18×10-06
Ppp1r35
Ppp1r35tm1.1(KOMP)Vlcg
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
JAX
IMPC
3.24×10-06
Enc1
Enc1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
3.63×10-06
Tnks
Tnksem1(IMPC)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
4.20×10-06
Tnks
Tnksem1(IMPC)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
4.28×10-06
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
4.32×10-06
Ncaph
Ncaphtm1a(EUCOMM)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
4.78×10-06
Trim56
Trim56tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
4.83×10-06
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
EuroPhenome
5.00×10-06
Dusp26
Dusp26tm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
5.04×10-06
4933434E20Rik
4933434E20Riktm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.07×10-06
Cbx6
Cbx6tm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.10×10-06
Fermt2
Fermt2tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
EuroPhenome
5.24×10-06
Tex261
Tex261tm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.33×10-06
Txndc5
Txndc5tm1.1(KOMP)Vlcg
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
5.45×10-06
Dscc1
Dscc1tm1a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
5.61×10-06
Slc38a2
Slc38a2tm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.81×10-06
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
JAX
IMPC
5.83×10-06
Cracdl
Cracdltm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
6.01×10-06
Atad3a
Atad3atm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
6.13×10-06
Abcb4
Abcb4em1(IMPC)H
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MRC Harwell
IMPC
6.23×10-06
Trim56
Trim56tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
6.28×10-06
Lactb
Lactbtm1.1(KOMP)Mbp
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
6.76×10-06
Pcsk5
Pcsk5tm1b(KOMP)Mbp
HET Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
6.80×10-06
Pcsk5
Pcsk5tm1b(KOMP)Mbp
HET Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
7.08×10-06
Dlg2
Dlg2tm1Dsb
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
7.31×10-06
Pex3
Pex3tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
7.84×10-06
Baz1b
Baz1btm2a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
EuroPhenome
7.85×10-06
Dync1i2
Dync1i2tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
8.12×10-06
Mms22l
Mms22ltm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
8.81×10-06
Trmt1
Trmt1tm1b(EUCOMM)Hmgu
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
9.00×10-06
Sidt2
Sidt2em1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
9.06×10-06
Pcdhb13
Pcdhb13em1(IMPC)Tcp
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
TCP
IMPC
9.14×10-06
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
9.48×10-06
Ppp1r35
Ppp1r35tm1.1(KOMP)Vlcg
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
JAX
IMPC
9.73×10-06
Rgp1
Rgp1tm1.1(KOMP)Vlcg
HET   Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
1.03×10-05
Ngdn
Ngdntm1b(EUCOMM)Wtsi
HET   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
1.07×10-05
Rab36
Rab36tm1b(KOMP)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
1.10×10-05
Amfr
Amfrtm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.11×10-05
Cenph
Cenphtm1b(EUCOMM)Hmgu
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
1.13×10-05
Setd1b
Setd1btm1.2(IMPC)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.17×10-05
Cyfip1
Cyfip1tm2a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.19×10-05
Atp11a
Atp11atm1a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.21×10-05
Cdk12
Cdk12em1(IMPC)Tcp
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
TCP
IMPC
1.24×10-05
Amfr
Amfrtm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
1.26×10-05
Elk4
Elk4tm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
HMGU
EuroPhenome
1.35×10-05
Ncaph
Ncaphtm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
1.36×10-05
Fbf1
Fbf1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.40×10-05
Rnf10
Rnf10tm1b(KOMP)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
1.43×10-05
Krtap17-1
Krtap17-1tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
1.48×10-05
Bzw2
Bzw2tm1b(KOMP)Mbp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
1.49×10-05
Enc1
Enc1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.51×10-05
Esco1
Esco1tm1(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.52×10-05
Krt7
Krt7tm1b(KOMP)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.57×10-05
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
EuroPhenome
1.58×10-05
Pkn2
Pkn2tm1b(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
1.60×10-05
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
1.61×10-05
Cyb561
Cyb561tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
EuroPhenome
1.66×10-05
Ddx51
Ddx51tm1a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
1.67×10-05
Setd1b
Setd1btm1.2(IMPC)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.69×10-05
Pnpt1
Pnpt1tm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
1.72×10-05
Kat2b
Kat2bem1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.73×10-05
Gpr146
Gpr146em1(IMPC)H
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
IMPC
1.77×10-05
Adgrf5
Adgrf5tm1b(KOMP)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
TCP
IMPC
1.77×10-05
Atp11a
Atp11atm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.81×10-05
Wrap53
Wrap53tm1b(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
1.95×10-05
H2-M5
H2-M5tm1(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
1.99×10-05
Sec24a
Sec24atm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.04×10-05
Atad2b
Atad2btm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
2.08×10-05
Mms22l
Mms22ltm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.10×10-05
Emcn
Emcnem1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
2.15×10-05
Ppp5c
Ppp5ctm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
2.16×10-05
Sidt2
Sidt2em1(IMPC)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
2.19×10-05
Aldh2
Aldh2tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
EuroPhenome
2.27×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
2.49×10-05
Etv6
Etv6em1(IMPC)Rbrc
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
RBRC
IMPC
2.53×10-05
Tagap1
Tagap1em1(IMPC)Tcp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
TCP
IMPC
2.54×10-05
C2cd4b
C2cd4bem1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
2.61×10-05
Wdtc1
Wdtc1tm1a(KOMP)Wtsi
HOM   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
2.62×10-05
Tox
Toxtm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
2.63×10-05
Kat2b
Kat2bem1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
2.73×10-05
Mms22l
Mms22ltm1a(EUCOMM)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.76×10-05
Adam3
Adam3tm1(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
2.78×10-05
Arhgef4
Arhgef4tm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
2.79×10-05
Hells
Hellstm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Fasted Clinical Chemistry
HMGU
EuroPhenome
2.85×10-05
Esco1
Esco1tm1(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
2.87×10-05
Bhlhe40
Bhlhe40tm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
2.89×10-05
Rhd
Rhdtm1e(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
WTSI
EuroPhenome
3.10×10-05
Setbp1
Setbp1tm1b(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
3.11×10-05
Tmod1
Tmod1tm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
3.19×10-05
Morc2a
Morc2aem1(IMPC)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.29×10-05
Abhd8
Abhd8tm1b(EUCOMM)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
BCM
IMPC
3.38×10-05
Camsap3
Camsap3tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.40×10-05
Myh7b
Myh7btm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
3.52×10-05
Krtap17-1
Krtap17-1tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
UC Davis
IMPC
3.62×10-05
Dscc1
Dscc1tm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
3.67×10-05
Col18a1
Col18a1tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
JAX
IMPC
3.69×10-05
Fto
Ftotm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
3.76×10-05
Abhd14a
Abhd14atm2a(EUCOMM)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.79×10-05
Bspry
Bsprytm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
EuroPhenome
3.79×10-05
Pkn2
Pkn2tm1b(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
3.81×10-05
Padi4
Padi4em1(IMPC)Mbp
HOM Late adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
3.84×10-05
Fbf1
Fbf1tm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.87×10-05
Tmem42
Tmem42tm1b(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
3.89×10-05
Pigh
Pightm1.1(KOMP)Vlcg
HET Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
3.93×10-05
Gpr146
Gpr146em1(IMPC)H
HOM   Late adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
IMPC
4.02×10-05
Dscc1
Dscc1tm1a(KOMP)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
4.03×10-05
Becn1
Becn1tm1b(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
4.10×10-05
Dnajc10
Dnajc10tm1a(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Fasted Clinical Chemistry
MRC Harwell
EuroPhenome
4.39×10-05
Ube2d1
Ube2d1tm3e(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
4.46×10-05
Dmxl2
Dmxl2tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
4.53×10-05
Susd6
Susd6tm1b(KOMP)Wtsi
HOM   Late adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
MRC Harwell
IMPC
4.72×10-05
Rundc1
Rundc1tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
4.81×10-05
Kif21b
Kif21btm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
5.09×10-05
Sidt2
Sidt2em1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.22×10-05
Gatm
Gatmtm1b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
5.26×10-05
Mier1
Mier1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Fasted Clinical Chemistry
WTSI
EuroPhenome
5.28×10-05
Eps8l2
Eps8l2tm1b(EUCOMM)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
MRC Harwell
IMPC
5.29×10-05
Sgo1
Sgo1tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
EuroPhenome
5.31×10-05
Tuft1
Tuft1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
5.35×10-05
Emcn
Emcnem1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.45×10-05
Aak1
Aak1tm1b(EUCOMM)Hmgu
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
5.63×10-05
Rhd
Rhdtm1e(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Fasted Clinical Chemistry
WTSI
EuroPhenome
5.73×10-05
Psg20
Psg20em1(IMPC)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.74×10-05
Cyp27a1
Cyp27a1tm1.1(KOMP)Vlcg
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
UC Davis
IMPC
5.79×10-05
Gda
Gdatm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
5.87×10-05
Fto
Ftotm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
EuroPhenome
5.90×10-05
Pgam5
Pgam5tm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
ICS
IMPC
6.15×10-05
Wdtc1
Wdtc1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
6.48×10-05
Ngdn
Ngdntm1b(EUCOMM)Wtsi
HET   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
6.72×10-05
Wrap53
Wrap53tm1b(EUCOMM)Wtsi
HET Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
IMPC
6.77×10-05
Rab36
Rab36tm1b(KOMP)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL cholesterol
Plasma Chemistry
JAX
IMPC
6.79×10-05
Nucks1
Nucks1tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
HMGU
IMPC
6.92×10-05
Abcb11
Abcb11tm1a(EUCOMM)Hmgu
HOM   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Fasted Clinical Chemistry
HMGU
EuroPhenome
7.03×10-05
Dusp16
Dusp16em1(IMPC)Tcp
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
TCP
IMPC
7.04×10-05
Nucks1
Nucks1tm1b(EUCOMM)Hmgu
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
HMGU
IMPC
7.07×10-05
Cyb561
Cyb561tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
7.11×10-05
Celf4
Celf4tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
7.15×10-05
Cpgi15344
Cpgi15344tm1.1(NCC)WCS
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
7.16×10-05
Palm
Palmem1(IMPC)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
7.18×10-05
Pgam5
Pgam5tm1b(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
ICS
IMPC
7.37×10-05
Larp1
Larp1em1(IMPC)Mbp
HET   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
7.40×10-05
Sag
Sagtm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
7.66×10-05
C2cd4b
C2cd4bem1(IMPC)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
7.86×10-05
Ndufs3
Ndufs3tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
7.88×10-05
Ik
Ikem2(IMPC)KMPC
HET Late adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
KMPC
IMPC
7.92×10-05
Camsap3
Camsap3tm1a(EUCOMM)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
8.07×10-05
Cbx6
Cbx6tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
8.11×10-05
Ap4e1
Ap4e1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
8.38×10-05
Ccdc92
Ccdc92tm1b(KOMP)Mbp
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
UC Davis
IMPC
8.44×10-05
Zfp182
Zfp182tm1b(KOMP)Wtsi
HOM   Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
8.44×10-05
Rpia
Rpiatm1a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
IMPC
8.53×10-05
Slc38a2
Slc38a2tm1a(KOMP)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
8.82×10-05
Wdr47
Wdr47tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
EuroPhenome
8.84×10-05
Rab5c
Rab5ctm1a(EUCOMM)Wtsi
HET Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
9.02×10-05
Sgo1
Sgo1tm1a(EUCOMM)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
9.07×10-05
Rbpj
Rbpjtm1b(EUCOMM)Hmgu
HET   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
JAX
IMPC
9.17×10-05
Pabpc4
Pabpc4tm1a(KOMP)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
IMPC
9.24×10-05
Slc16a2
Slc16a2tm1a(KOMP)Wtsi
HEM   Early adult decreased circulating LDL cholesterol level LDL-cholesterol
Clinical Chemistry
WTSI
MGP
9.26×10-05
Abca6
Abca6tm2b(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
TCP
IMPC
9.28×10-05
Osm
Osmtm1b(KOMP)Wtsi
HOM   Early adult decreased circulating cholesterol level Total cholesterol
Plasma Chemistry
JAX
IMPC
9.44×10-05
Baz1b
Baz1btm2a(KOMP)Wtsi
HET Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
EuroPhenome
9.44×10-05
Pitpnm1
Pitpnm1tm1a(EUCOMM)Wtsi
HOM Early adult decreased circulating HDL cholesterol level HDL-cholesterol
Clinical Chemistry
WTSI
MGP
9.50×10-05
Rapgefl1
Rapgefl1tm1a(KOMP)Wtsi
HOM Early adult decreased circulating cholesterol level Total cholesterol
Clinical Chemistry
WTSI
MGP
9.86×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

3.24% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased circulating cholesterol level (176/5440)

0.57% females (30/5263) 2.75% males (144/5245)

Select a parameter    



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