Phenotype: increased eosinophil cell number

Definition
greater than normal eosinophil numbers
Synonyms
increased eosinophil number,  increased eosinophil count,  eosinophilia
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased eosinophil cell number

Total number of significant genotype-phenotype associations: 26

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Bach2
Bach2tm1a(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Spleen Immunophenotyping | Eosinophils - % of CD45+ WTSI | 3i 0.00
Cog6
Cog6tm1a(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Mesenteric Lymph Node Immunophenotyping | Eosinophils - % of CD45+ WTSI | 3i 0.00
Cxcr2
Cxcr2tm1a(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Spleen Immunophenotyping | Eosinophils - % of CD45+ WTSI | 3i 0.00
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM postnatal increased eosinophil cell number Mesenteric Lymph Node Immunophenotyping | Eosinophils - % of CD45+ WTSI | 3i 0.00
Usp15
Usp15em1(IMPC)Marc
HOM postnatal increased eosinophil cell number Hematology | Eosinophil cell count MARC | IMPC 2.49×10-11
Emc10
Emc10tm1b(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Hematology | Eosinophil differential count MRC Harwell | IMPC 2.21×10-08
Tnfrsf1a
Tnfrsf1atm2b(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Hematology | Eosinophil cell count MRC Harwell | IMPC 1.88×10-07
Zswim1
Zswim1tm1b(KOMP)Mbp
HOM postnatal increased eosinophil cell number Hematology | Eosinophil differential count MARC | IMPC 2.41×10-06
Herc1
Herc1em3(IMPC)Wtsi
HOM postnatal increased eosinophil cell number Whole blood peripheral blood leukocyte immunophenotyping | Eosinophil number WTSI | 3i 5.40×10-06
Slc16a3
Slc16a3tm1b(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Hematology | Eosinophil cell count MRC Harwell | IMPC 1.59×10-05
Arpc1b
Arpc1btm1a(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Whole blood peripheral blood leukocyte immunophenotyping | Eosinophil number WTSI | 3i 2.26×10-05
Mkrn2
Mkrn2tm1b(KOMP)Wtsi
HOM postnatal increased eosinophil cell number Whole blood peripheral blood leukocyte immunophenotyping | Eosinophil number WTSI | 3i 2.26×10-05
Itch
Itchtm1b(EUCOMM)Hmgu
HOM postnatal increased eosinophil cell number Hematology | Eosinophil differential count MRC Harwell | IMPC 2.79×10-05
Fbxo28
Fbxo28em1(IMPC)Mhzh
HET postnatal increased eosinophil cell number Hematology | Eosinophil cell count MARC | IMPC 6.90×10-05
Boc
Boctm1b(KOMP)Wtsi
HOM postnatal increased eosinophil cell number Hematology | Eosinophil cell count MRC Harwell | IMPC 7.13×10-05
Nrbp2
Nrbp2tm2b(EUCOMM)Wtsi
HOM postnatal increased eosinophil cell number Hematology | Eosinophil differential count MRC Harwell | IMPC 7.47×10-05
Rtraf
Rtraftm1b(EUCOMM)Hmgu
HET postnatal increased eosinophil cell number Hematology | Eosinophil cell count MRC Harwell | IMPC 7.76×10-05

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 The way we measure

 Phenotype associations stats

0.64% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased eosinophil cell number (17/2663)

0.46% females (12/2584) 0.39% males (10/2583)

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