MP:0003064 (decreased coping response) | IMPC Phenotype Information | International Mouse Phenotyping Consortium

Phenotype: decreased coping response

Definition

reduced ability to respond productively to a stressful situation

Synonyms

reduced coping response

of tested genes

significant genes

tested genes

Total number of significant genotype-phenotype associations: 9

Gene / Allele	Zygosity	Life Stage	Phenotype	Parameter	Phenotyping Center	P Value
Clvs1 Clvs1^{tm1.1(KOMP)Vlcg}	HOM	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	7.28×10^-07
Parp8 Parp8^{tm1.1(KOMP)Wtsi}	HOM	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	4.07×10^-06
Elof1 Elof1^{tm1.1(KOMP)Vlcg}	HET	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	9.55×10^-06
Fam161a Fam161a^{tm1b(KOMP)Wtsi}	HOM	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	1.83×10^-05
Mag Mag^{tm1.1(KOMP)Vlcg}	HOM	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	2.00×10^-05
Jup Jup^{tm1.1(KOMP)Vlcg}	HET	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	2.54×10^-05
Rrp8 Rrp8^{tm1.1(KOMP)Vlcg}	HET	Early adult	decreased coping response	Time immobile Tail Suspension	JAX IMPC	9.16×10^-05
Adad2 Adad2^em1(IMPC)J	HOM	Early adult	decreased coping response	Latency to immobility Tail Suspension	JAX IMPC	9.54×10^-05

Download data as: TSV XLS

Procedure
Rotarod
Tail Suspension

3.32% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased coping response (8/241)

1.63% females (4/245) 1.59% males (4/252)

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