Phenotype: increased startle reflex

Definition
reduced threshold or more severe reflex response to variable stimuli, often auditory; usually measured by amplitude of whole body flinch
Synonyms
increased startle response in acoustic startle test
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with increased startle reflex

Total number of significant genotype-phenotype associations: 392

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Elmod1
Elmod1tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
0.00
Mboat1
Mboat1em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.16×10-37
Aldh3a2
Aldh3a2tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.77×10-29
Pacs2
Pacs2tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.96×10-28
Fbxo11
Fbxo11Jf
HET Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.55×10-27
Clk2
Clk2em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.07×10-20
Wbp1l
Wbp1ltm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.53×10-20
Slc8a3
Slc8a3tm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.66×10-20
Ap4e1
Ap4e1tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.63×10-18
Atf7
Atf7tm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.90×10-18
Atxn7
Atxn7em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
3.08×10-18
Zfp13
Zfp13tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.35×10-17
Phldb2
Phldb2em1(IMPC)H
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.48×10-17
Rell1
Rell1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.59×10-17
Etl4
Etl4em1(IMPC)Bay
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
5.11×10-16
Ssbp2
Ssbp2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.62×10-16
Fkbp10
Fkbp10tm2a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.13×10-15
Mecom
MecomJbo
HET Early adult increased startle reflex PP1 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.55×10-15
Abcb4
Abcb4tm1Bor
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
7.15×10-15
Limk2
Limk2tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.52×10-14
Sema3f
Sema3ftm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.02×10-14
Setdb1
Setdb1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
1.28×10-13
Trpc3
Trpc3Mwk
HET Early adult increased startle reflex PP1 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.45×10-13
Syncrip
Syncriptm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.32×10-13
Cops4
Cops4tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.83×10-13
Hif1an
Hif1anem1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.20×10-12
Yipf1
Yipf1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
MGP
1.28×10-12
Trp53
Trp53tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.39×10-12
Notch1
Notch1tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
2.75×10-12
Cdk13
Cdk13tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.18×10-12
Nhs
Nhsem1(IMPC)Tcp
HEM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.44×10-12
Ephx1
Ephx1Ephx1
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
6.20×10-12
Grin2b
Grin2btm1e.1(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.12×10-12
Ncor2
Ncor2Ncor2
HOM Early adult increased startle reflex PP3 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.32×10-11
Kpna4
Kpna4em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.85×10-11
Zfp69
Zfp69tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.26×10-11
Zfp462
Zfp462em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.49×10-11
Vat1l
Vat1ltm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.13×10-10
Clk1
Clk1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.25×10-10
Secisbp2l
Secisbp2lem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.58×10-10
Ppargc1a
Ppargc1aem1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.71×10-10
Rab5a
Rab5atm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.19×10-10
Nhs
Nhsem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.26×10-10
Becn1
Becn1tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.58×10-10
Mob2
Mob2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
4.74×10-10
Mtarc2
Mtarc2tm2a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
6.35×10-10
Peak1
Peak1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.96×10-10
Otoa
Otoatm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.54×10-10
Gins4
Gins4tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
9.18×10-10
Pkn2
Pkn2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.18×10-09
Lrrc41
Lrrc41em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.49×10-09
F2rl1
F2rl1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.78×10-09
Dgkk
Dgkkem1(IMPC)Ics
HEM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
2.16×10-09
Sox13
Sox13tm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.53×10-09
Mat2a
Mat2atm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.62×10-09
Rprd1b
Rprd1btm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.49×10-09
Kcnj10
Kcnj10tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
4.76×10-09
Prpsap2
Prpsap2tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.03×10-09
Nol8
Nol8tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
6.46×10-09
Herpud2
Herpud2tm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.77×10-09
Abcc5
Abcc5em1(IMPC)H
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
6.78×10-09
Thra
Thratm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.04×10-09
Cacnb4
Cacnb4tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
7.57×10-09
Cct3
Cct3em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
9.17×10-09
Nipsnap1
Nipsnap1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP1 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.03×10-08
Bex2
Bex2tm1b(EUCOMM)Hmgu
HEM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.27×10-08
Zfp715
Zfp715tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.52×10-08
Nsd3
Nsd3tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.60×10-08
Susd6
Susd6tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.79×10-08
Tmem255b
Tmem255btm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.35×10-08
Ubr7
Ubr7em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.48×10-08
Ctnnb1
Ctnnb1Bfc
HET Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.51×10-08
Wbp2
Wbp2tm2a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.97×10-08
Dym
Dymem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.06×10-08
Ube2h
Ube2htm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
3.55×10-08
Atp1b1
Atp1b1em1(IMPC)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.00×10-08
Colec12
Colec12em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.07×10-08
Cgas
Cgastm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.09×10-08
Shh
Shhtm1Chg
HET Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.41×10-08
Iqgap2
Iqgap2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.44×10-08
Hint1
Hint1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.75×10-08
Vdac1
Vdac1tm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.10×10-08
Fam43a
Fam43aem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.86×10-08
Pcm1
Pcm1em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.09×10-08
Arvcf
Arvcftm1e(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
6.46×10-08
Rpe65
Rpe65tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
6.52×10-08
Farp1
Farp1tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.68×10-08
Fgf9
Fgf9tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.57×10-08
Armt1
Armt1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
8.60×10-08
Cldn11
Cldn11em1(IMPC)H
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
9.11×10-08
Bfsp1
Bfsp1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
9.69×10-08
Ncoa7
Ncoa7tm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.01×10-07
Spg11
Spg11em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.02×10-07
Zmym2
Zmym2em1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.02×10-07
Ccnt1
Ccnt1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.08×10-07
Ptpra
Ptpratm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.14×10-07
Rab5b
Rab5bem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.29×10-07
Enpep
Enpeptm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.29×10-07
Rps26
Rps26tm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.38×10-07
Ift81
Ift81tm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.45×10-07
Sgsh
Sgshem3(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.45×10-07
Cpe
Cpetm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.52×10-07
Rnf187
Rnf187em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.63×10-07
Rgl1
Rgl1em1(IMPC)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.22×10-07
Sarnp
Sarnptm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.51×10-07
Fpgs
Fpgstm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.97×10-07
Septin8
Septin8tm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.07×10-07
Itgb1
Itgb1em1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
3.15×10-07
0610010K14Rik
0610010K14Riktm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.29×10-07
Gar1
Gar1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.59×10-07
Mybbp1a
Mybbp1atm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.60×10-07
Prkg1
Prkg1tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.69×10-07
Slc4a10
Slc4a10tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.74×10-07
Myc
Mycem1(IMPC)Kmpc
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
4.12×10-07
Fam161a
Fam161atm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.13×10-07
Capn5
Capn5tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.24×10-07
Tpm1
Tpm1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP2 startle magnitude
Acoustic Startle&PPI
WTSI
EuroPhenome
4.53×10-07
Gsta3
Gsta3tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.67×10-07
Ubn1
Ubn1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.87×10-07
Atp8a1
Atp8a1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
5.08×10-07
Chrna9
Chrna9tm2a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
5.41×10-07
Cant1
Cant1tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
6.34×10-07
Gnas
Gnastm1Jop
HOM Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
6.97×10-07
Ficd
Ficdtm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
6.97×10-07
Zfp629
Zfp629em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.98×10-07
Cdc37
Cdc37em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.08×10-07
Ppy
Ppytm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.26×10-07
Stim2
Stim2tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.61×10-07
Brpf1
Brpf1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
8.68×10-07
Gmeb2
Gmeb2em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.75×10-07
Ttc17
Ttc17em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.37×10-07
Wtap
Wtaptm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.03×10-06
H6pd
H6pdtm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.06×10-06
Senp7
Senp7tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
1.13×10-06
Zfp91
Zfp91em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.17×10-06
H2az1
H2az1em1(IMPC)J
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.18×10-06
Mtmr3
Mtmr3tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.20×10-06
Tdrkh
Tdrkhtm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.27×10-06
Crtc1
Crtc1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.29×10-06
Pmel
Pmeltm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.32×10-06
Gm12258
Gm12258tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.38×10-06
Ajap1
Ajap1tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.42×10-06
Hgsnat
Hgsnatem4(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.55×10-06
Fkbp1b
Fkbp1btm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
1.58×10-06
Sema5b
Sema5btm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.58×10-06
Spryd3
Spryd3tm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
1.63×10-06
Cd84
Cd84tm1b(KOMP)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.71×10-06
E2f3
E2f3tm1b(KOMP)Wtsi
HET   Late adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
1.76×10-06
Itk
Itkem1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.90×10-06
Zmym2
Zmym2em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.05×10-06
Ngfr
Ngfrtm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.10×10-06
Lnpk
Lnpkem1(IMPC)Bay
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
2.13×10-06
Parvb
Parvbtm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.26×10-06
H3f3b
H3f3btm1.1(KOMP)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.34×10-06
Frmd5
Frmd5tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
2.38×10-06
Epb41l5
Epb41l5tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.39×10-06
Il1a
Il1atm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.52×10-06
Slc4a8
Slc4a8em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.01×10-06
Oplah
Oplahtm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.28×10-06
Dis3
Dis3tm1e.1(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.32×10-06
Phykpl
Phykpltm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex BN startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.33×10-06
Exoc3l
Exoc3lem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.39×10-06
Dach1
Dach1tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.44×10-06
Chrm4
Chrm4tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.52×10-06
Llgl2
Llgl2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.80×10-06
Lhx1
Lhx1tm1e(EUCOMM)Wtsi
HET   Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.15×10-06
Bahd1
Bahd1tm2b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
4.46×10-06
Grhl3
Grhl3tm1a(EUCOMM)Wtsi
HET   Early adult increased startle reflex BN startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.48×10-06
Moxd1
Moxd1tm2b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.56×10-06
Cyp7a1
Cyp7a1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.60×10-06
Xylb
Xylbtm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.63×10-06
Abhd15
Abhd15tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
4.68×10-06
Acbd3
Acbd3tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.69×10-06
Plekha5
Plekha5em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.90×10-06
Igf2bp3
Igf2bp3em1(IMPC)J
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.22×10-06
Dagla
Daglatm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
5.27×10-06
Ascc3
Ascc3tm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.49×10-06
Epb41l1
Epb41l1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.80×10-06
Bltp1
Bltp1tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.81×10-06
Ifit3
Ifit3em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.25×10-06
Col11a2
Col11a2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
6.25×10-06
Mtmr14
Mtmr14tm1a(KOMP)Wtsi
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
6.77×10-06
Iffo2
Iffo2em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.80×10-06
Nufip2
Nufip2em1(IMPC)J
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.10×10-06
Sirt6
Sirt6tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP2 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.63×10-06
Parl
Parltm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.80×10-06
Ryr2
Ryr2tm1b(KOMP)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
7.84×10-06
Dnajb11
Dnajb11tm1b(EUCOMM)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.11×10-06
Dusp7
Dusp7tm1(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
8.12×10-06
Cdc123
Cdc123tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.50×10-06
Grhl2
Grhl2em1(IMPC)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.56×10-06
Brix1
Brix1tm1b(KOMP)Mbp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
8.59×10-06
Rnaseh2a
Rnaseh2aem1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
9.07×10-06
Nr1h4
Nr1h4Nr1h4
HOM   Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
9.30×10-06
Zbtb5
Zbtb5tm2b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
9.40×10-06
Gna11
Gna11tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
9.54×10-06
Ubl7
Ubl7em1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
9.60×10-06
Mcf2l
Mcf2ltm1a(EUCOMM)Hmgu
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.01×10-05
Pum2
Pum2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.01×10-05
Brms1
Brms1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.14×10-05
Zfp119a
Zfp119atm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.19×10-05
Kcnj12
Kcnj12tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.19×10-05
Uchl1
Uchl1tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.24×10-05
Gm5134
Gm5134tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.26×10-05
Slc29a3
Slc29a3em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.29×10-05
Atp6v0d1
Atp6v0d1tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.38×10-05
Tnks2
Tnks2tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.41×10-05
Mipep
Mipepem1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.43×10-05
Ddx52
Ddx52tm1a(EUCOMM)Wtsi
HET   Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.44×10-05
Zbtb24
Zbtb24tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.44×10-05
Btbd2
Btbd2em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
1.50×10-05
Rbfox3
Rbfox3tm1a(EUCOMM)Hmgu
HOM Early adult increased startle reflex PP3 startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
1.53×10-05
Golga5
Golga5tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.71×10-05
Bex2
Bex2tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
1.74×10-05
Cdkn2aip
Cdkn2aipem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.75×10-05
Rcc1l
Rcc1ltm1a(EUCOMM)Hmgu
HET   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
1.79×10-05
Cox20
Cox20em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
1.83×10-05
Tmem72
Tmem72tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
1.91×10-05
Drg2
Drg2tm1a(EUCOMM)Wtsi
HOM   Early adult increased startle reflex PP1 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
1.92×10-05
Zbtb12
Zbtb12em1(IMPC)J
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
1.94×10-05
Phlpp2
Phlpp2em1(IMPC)H
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
1.98×10-05
Dbnl
Dbnltm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
1.98×10-05
Sufu
Sufutm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.13×10-05
Lama1
Lama1tm2b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.19×10-05
Bcl2l15
Bcl2l15tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.21×10-05
Akr7a5
Akr7a5tm1b(EUCOMM)Hmgu
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.21×10-05
Pspc1
Pspc1em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.22×10-05
Slc5a5
Slc5a5tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.29×10-05
Nr3c2
Nr3c2Nr3c2
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
2.31×10-05
Lclat1
Lclat1em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.37×10-05
Cartpt
Cartptem1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.37×10-05
Dnaja1
Dnaja1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.41×10-05
Nlk
Nlktm2b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
2.53×10-05
Gnptg
Gnptgem1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.58×10-05
Msh5
Msh5tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
2.64×10-05
Kif1b
Kif1btm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.79×10-05
Vps13b
Vps13bem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
2.84×10-05
Ube2o
Ube2otm1.1(KOMP)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
2.89×10-05
Hbp1
Hbp1not yet available
HET Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
2.93×10-05
Id3
Id3em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
2.99×10-05
Snap23
Snap23tm1b(EUCOMM)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.02×10-05
Tmco3
Tmco3tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.05×10-05
Nfatc3
Nfatc3tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.10×10-05
Tnfaip1
Tnfaip1tm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.12×10-05
Gsto1
Gsto1em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.20×10-05
Jmjd6
Jmjd6tm1b(EUCOMM)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.26×10-05
Fam83g
Fam83gtm1a(EUCOMM)Wtsi
HOM Early adult increased startle reflex PP2 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
3.32×10-05
Boc
Boctm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
3.34×10-05
Psen1
Psen1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.46×10-05
Nr1d2
Nr1d2tm1Dgen
HOM Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
3.49×10-05
Chst12
Chst12em1(IMPC)Marc
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MARC
IMPC
3.60×10-05
Naaladl2
Naaladl2em1(IMPC)Tcp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
3.63×10-05
Ube2a
Ube2atm1.1(KOMP)Vlcg
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.65×10-05
Afap1l2
Afap1l2tm1b(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.69×10-05
Nolc1
Nolc1tm1b(EUCOMM)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
3.73×10-05
Marchf7
Marchf7March7
HOM Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
3.82×10-05
Mapk6
Mapk6em1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.85×10-05
Rab10
Rab10em1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.89×10-05
Jakmip2
Jakmip2em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
3.93×10-05
Rabl2
Rabl2tm1.1(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
3.97×10-05
Paqr6
Paqr6tm1b(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
4.01×10-05
Gcgr
Gcgrtm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.06×10-05
Slc25a10
Slc25a10tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
4.12×10-05
Nr6a1
Nr6a1Nr6a1
HET Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.12×10-05
Esd
Esdem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.19×10-05
Esrra
Esrratm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.28×10-05
Ss18
Ss18em1(IMPC)J
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
4.41×10-05
Npc1
Npc1tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
4.52×10-05
Setdb2
Setdb2tm1a(KOMP)Wtsi
HOM   Early adult increased startle reflex PP4 + pulse startle magnitude
Acoustic Startle&PPI
HMGU
EuroPhenome
4.57×10-05
Ppil1
Ppil1em1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
4.76×10-05
Strap
StrapStrap
HET Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
4.78×10-05
Clptm1
Clptm1em1(IMPC)Tcp
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
4.83×10-05
Stambp
Stambptm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
MRC Harwell
IMPC
5.26×10-05
Churc1
Churc1tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
CCP-IMG
IMPC
5.27×10-05
Hmbs
Hmbstm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.58×10-05
Timp4
Timp4em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
5.61×10-05
Tmub2
Tmub2tm1b(KOMP)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
5.64×10-05
Arsj
Arsjem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.78×10-05
Arrb1
Arrb1tm1b(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.81×10-05
Col5a1
Col5a1tm1a(EUCOMM)Hmgu
HET Early adult increased startle reflex PP4 startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
5.88×10-05
Miga1
Miga1tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
5.91×10-05
Meis1
Meis1tm1b(EUCOMM)Hmgu
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
5.98×10-05
Ang
Angtm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.00×10-05
Plscr1
Plscr1tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
6.02×10-05
Pkig
Pkigtm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
6.04×10-05
Fbxo41
Fbxo41tm1.1(KOMP)Vlcg
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.26×10-05
Cd22
Cd22tm1b(EUCOMM)Wtsi
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.76×10-05
Irgc
Irgcem1(IMPC)Tcp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
TCP
IMPC
6.77×10-05
Taf15
Taf15em1(IMPC)Mbp
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.81×10-05
Cdkn2aip
Cdkn2aipem1(IMPC)J
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.83×10-05
Cttnbp2nl
Cttnbp2nlem1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
6.90×10-05
Ebf1
Ebf1em1(IMPC)Mbp
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
6.92×10-05
Cndp2
Cndp2em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
7.09×10-05
Rilpl1
Rilpl1tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.30×10-05
Spryd3
Spryd3tm1b(EUCOMM)Hmgu
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.54×10-05
Atp13a3
Atp13a3em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
7.60×10-05
Tap1
Tap1tm2b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
7.84×10-05
Sfrp2
Sfrp2C50F
HOM Early adult increased startle reflex BN startle magnitude
Acoustic Startle&PPI
MRC Harwell
EuroPhenome
7.85×10-05
Anxa6
Anxa6tm1(NCOM)Cmhd
HOM Early adult increased startle reflex 110dB startle magnitude
Acoustic Startle&PPI
CMHD
EuroPhenome
8.00×10-05
Dnaaf2
Dnaaf2tm1.1(KOMP)Vlcg
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.01×10-05
Spta1
Spta1em1(IMPC)Bay
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
BCM
IMPC
8.16×10-05
Ube2m
Ube2mtm1.1(KOMP)Wtsi
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.23×10-05
Casp2
Casp2em1(IMPC)Mbp
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
UC Davis
IMPC
8.27×10-05
Sgip1
Sgip1tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
8.34×10-05
Ube2j2
Ube2j2em1(IMPC)Rbrc
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
RBRC
IMPC
8.48×10-05
Ttll1
Ttll1tm1a(EUCOMM)Wtsi
HET Early adult increased startle reflex PP3 + pulse startle magnitude
Acoustic Startle&PPI
ICS
EuroPhenome
8.53×10-05
Spin1
Spin1tm1.1(KOMP)Vlcg
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.65×10-05
Cyb5d2
Cyb5d2tm1.1(KOMP)Wtsi
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
8.94×10-05
Eftud2
Eftud2tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
ICS
IMPC
9.12×10-05
Gng12
Gng12em1(IMPC)J
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.30×10-05
Npas3
Npas3tm1b(KOMP)Wtsi
HET Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
KMPC
IMPC
9.49×10-05
Gsta4
Gsta4tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
9.51×10-05
Dhx30
Dhx30tm1.1(KOMP)Vlcg
HET   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.52×10-05
Zfp422
Zfp422em1(IMPC)J
HOM Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
JAX
IMPC
9.83×10-05
Ostf1
Ostf1tm1b(EUCOMM)Hmgu
HOM   Early adult increased startle reflex Response amplitude - S
Acoustic Startle and Pre-pulse Inhibition (PPI)
HMGU
IMPC
9.89×10-05

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 The way we measure

 Phenotype associations stats

4.57% of tested genes with null mutations on a B6N genetic background have a phenotype association to increased startle reflex (310/6786)

1.57% females (109/6927) 2.99% males (207/6921)

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