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Phenotype: convulsive seizures

Definition
seizures characterized by uncontrolled motor activity
Synonyms
convulsions,  Convulsive
Significant gene associations The way we measure Phenotype stats
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with convulsive seizures

Total number of significant genotype-phenotype associations: 10

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center		 P Value
Mag
Magtm1.1(KOMP)Vlcg 		HOM Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 3.70×10-15
Tppp
Tppptm1.1(KOMP)Vlcg 		HOM Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 8.64×10-15
Dnmt3a
Dnmt3atm1b(KOMP)Wtsi 		HET Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 1.49×10-12
Rnf10
Rnf10tm1b(KOMP)Wtsi 		HOM Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 2.91×10-06
Cyb5d1
Cyb5d1tm1.1(KOMP)Vlcg 		HOM   Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 5.41×10-06
Adora2b
Adora2btm1.1(KOMP)Vlcg 		HET   Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 6.20×10-06
Myo3b
Myo3btm1b(EUCOMM)Hmgu 		HOM Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 2.99×10-05
Zfp14
Zfp14tm1b(KOMP)Wtsi 		HOM Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 5.27×10-05
Loxl1
Loxl1tm1.1(KOMP)Vlcg 		HOM   Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 7.10×10-05
Nrcam
Nrcamtm2e.1(KOMP)Wtsi 		HOM Early adult convulsive seizures mA threshold inducing clonic seizure
Electroconvulsive Threshold Testing		 JAX
IMPC		 7.49×10-05

Download data as:   TSV   XLS

 The way we measure

Procedure
Combined SHIRPA and Dysmorphology
Electroconvulsive Threshold Testing

 Phenotype associations stats

0.68% of tested genes with null mutations on a B6N genetic background have a phenotype association to convulsive seizures (10/1464)

0.41% females (6/1462) 0.07% males (1/1459)



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