Phenotype: abnormal femur morphology

Definition
any structural anomaly of the long bone of the thigh
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with abnormal femur morphology

Total number of significant genotype-phenotype associations: 45

Gene / Allele Zygosity Sex Life Stage Phenotype Procedure | Parameter Phenotyping Center | Source P Value
Duoxa2
Duoxa2tm1b(KOMP)Wtsi
HOM Early adult abnormal femur morphology X-ray | Femur WTSI | IMPC 1.25×10-32
Sik3
Sik3tm1a(EUCOMM)Hmgu
HOM Early adult abnormal femur morphology X-ray | Femur WTSI | IMPC 1.25×10-32
Col9a2
Col9a2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal femur morphology X-ray | Femur MRC Harwell | IMPC 2.61×10-25
Lrrk1
Lrrk1tm1b(KOMP)Wtsi
HOM Early adult abnormal femur morphology X-ray | Femur MRC Harwell | IMPC 2.61×10-25
Cyp27b1
Cyp27b1tm1b(EUCOMM)Hmgu
HOM Early adult abnormal femur morphology X-ray | Femur TCP | IMPC 4.32×10-25
Fbn2
Fbn2em1(IMPC)Rbrc
HOM Early adult abnormal femur morphology X-ray | Femur RBRC | IMPC 1.45×10-21
Mysm1
Mysm1tm1a(KOMP)Wtsi
HOM Early adult abnormal femur morphology X-Ray | Femur WTSI | EuroPhenome 1.49×10-17
Tent5a
Tent5aem1(IMPC)Ccpcz
HOM Early adult abnormal femur morphology X-ray | Femur CCP-IMG | IMPC 3.00×10-14
Dnase1l2
Dnase1l2tm1.1(KOMP)Wtsi
HOM Early adult abnormal femur morphology X-ray | Shape of femur WTSI | MGP 9.89×10-14
Phex
Phexnot yet available
HOM Early adult abnormal femur morphology X-Ray | Femur HMGU | EuroPhenome 1.02×10-13
Slc38a2
Slc38a2tm1a(KOMP)Wtsi
HET Early adult abnormal femur morphology X-ray | Femur WTSI | IMPC 1.80×10-09
Timp1
Timp1tm1b(EUCOMM)Hmgu
HEM Early adult abnormal femur morphology X-ray | Femur MRC Harwell | IMPC 2.94×10-09
Bnip2
Bnip2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal femur morphology X-ray | Femur WTSI | IMPC 1.96×10-07
Col1a2
Col1a2tm1b(EUCOMM)Wtsi
HOM Early adult abnormal femur morphology X-ray | Femur BCM | IMPC 5.91×10-07
Fbxl7
Fbxl7tm1a(EUCOMM)Wtsi
HOM Early adult abnormal femur morphology Cortical Bone MicroCT | Internal Diameter WTSI | IMPC 1.15×10-06
Sh3pxd2a
Sh3pxd2atm1b(EUCOMM)Wtsi
HET Early adult abnormal femur morphology Femoral Microradiography | Femur Length WTSI | IMPC 8.90×10-06
Ctrc
Ctrctm1b(EUCOMM)Hmgu
HOM Early adult abnormal femur morphology X-ray | Femur HMGU | IMPC 2.36×10-05
Ap4e1
Ap4e1tm1a(KOMP)Wtsi
HOM Early adult abnormal femur morphology X-ray | Shape of femur WTSI | MGP 3.31×10-05
Chpf
Chpftm1b(EUCOMM)Hmgu
HOM Early adult abnormal femur morphology X-ray | Femur HMGU | IMPC 3.34×10-05
Polr1a
Polr1atm1b(EUCOMM)Hmgu
HET Early adult abnormal femur morphology X-ray | Femur BCM | IMPC 6.90×10-05

Download data as:   TSV   XLS

 The way we measure

 Phenotype associations stats

0.39% of tested genes with null mutations on a B6N genetic background have a phenotype association to abnormal femur morphology (20/5149)

0.43% females (9/2092) 0.76% males (16/2093)

Select a parameter    



The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter