Eye Morphology: Images Ophthalmoscopy

WT Images

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: LEFT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia ; LEFT EYE: A little bit of Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate dysplasia

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia; LEFT EYE: Slight opacity on lens, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate Rd8/dysplasia

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; LEFT EYE:,
Ophthalmoscope Observation: R eye severe rd8. L eye some rd8 and slight opacity.; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Severe rd8,
Ophthalmoscope Observation: LEFT EYE: Severe rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

57 weeks old

Ophthalmoscope Observation: RIGHT EYE: Severe Rd8; LEFT EYE: Slight lens opacity, difficulty focusing, some Rd8,
Ophthalmoscope Observation: RIGHT EYE: Severe Rd8

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight opacity on lens

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens; LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: LEFT EYE: Some rd8, slight opacity on lens,
Ophthalmoscope Observation: RIGHT EYE: Slight opacity on lens

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

58 weeks old

Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; LEFT EYE:,
Ophthalmoscope Observation: Both eyes Slight opacity on lens, hard to focus; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: Both eyes some rd8,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

58 weeks old

Ophthalmoscope Observation: RIGHT EYE: Some rd8; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Some rd8

Mutant Images

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Severe lens opacity; no image and data.,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Severe lens opacity; no image and data.,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; RIGHT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; LEFT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; RIGHT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; RIGHT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia; LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE: White patches/lesions bottom left,
Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging ; LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging ; LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging ; LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia; LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; LEFT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE: White patches/lesions bottom left,
Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.; LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia; LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.; LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE: White patches/lesions bottom left,
Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE: White patches/lesions bottom left,
Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging ; LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.; LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE: White patches/lesions bottom left,
Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; RIGHT EYE: Some hemorrhaging,
Ophthalmoscope Observation: Both eyes some dysplasia and slight lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Moderate lens opacity (difficult to image and focus).Hyaloid present; moderate rd8.

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both moderate rd8 ; RIGHT EYE: Slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; RIGHT EYE: White patches/lesions bottom left,
Ophthalmoscope Observation: Both eyes moderate rd8 and some lens opacity (difficult to focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging ; LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; LEFT EYE: Some rd8, and abnormal curved blood vessel and white dashes, and lesions near optic nerve,
Ophthalmoscope Observation: Both eyes severe lens opacity, hyaloid present ; RIGHT EYE: Opacity obstruct the view, difficult to focus and imagine

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8; LEFT EYE: Severe lens opacity; no image and data.,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging ; LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Moderate rd8 and slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Severe rd8 and some hemorrhaging

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; LEFT EYE: Some rd8 and dysplasia,
Ophthalmoscope Observation: Both eyes some lens opacity (difficult to focus).; RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 and slight lens opacity; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; RIGHT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; LEFT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage ; LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; RIGHT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).; LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity.,
Ophthalmoscope Observation: RIGHT EYE: Crystalline debris/patches on the lens (some retinal obstruction and difficult to image and focus).

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8; LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, moderate rd8 and a small lesion on the right of optic nerve,
Ophthalmoscope Observation: RIGHT EYE: Lens opacity, difficult to focus. Hyaloid present and some rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia; LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8; LEFT EYE: Some lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes severe rd8; RIGHT EYE:

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; RIGHT EYE: Some rd8,
Ophthalmoscope Observation: Both eyes lens opacity (difficult to image and focus).; LEFT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia; LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; LEFT EYE: Some lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8 and dysplasia; RIGHT EYE: Bright spot in lens difficult to focus

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia; LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: LEFT EYE: Some rd8 and small white specks near vessels,
Ophthalmoscope Observation: RIGHT EYE: Slight lens opacity some dysplasia

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; LEFT EYE: Some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some lens opacity, difficult to focus; some dysplasia; RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Small lesion below optic nerve,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Small hyaloid present, lens opacity

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Moderate rd8 ; LEFT EYE: Some rd8,
Ophthalmoscope Observation: LEFT EYE: Some rd8,
Ophthalmoscope Observation: RIGHT EYE: Moderate rd8

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.; LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: LEFT EYE: Some rd8, dysplasia and lens opacity (difficult to focus).,
Ophthalmoscope Observation: RIGHT EYE: Severe opacity; no image and data.

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; LEFT EYE: Some dysplasia, difficult to focus,
Ophthalmoscope Observation: Both eyes some lens opacity ; RIGHT EYE: Severe rd8, slight hemorrhage

58 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes severe rd8,
Ophthalmoscope Observation: Both eyes severe rd8 ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes severe rd8 ; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity (difficult to focus).; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

57 weeks old

Top2aem2(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; LEFT EYE: Some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8 and slight lens opacity ( difficult to focus).; RIGHT EYE:

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