Gene: Top2a

Log in to follow

Name
topoisomerase (DNA) II alpha
MGI ID
MGI:98790
Synonyms
Top-2 DNA Topoisomerase II alpha
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal lens morphology Top2aem2(IMPC)Tcp HET Late adult 4.01×10-06
preweaning lethality, complete penetrance Top2aem2(IMPC)Tcp HOM Early adult 0.00
embryonic lethality prior to organogenesis Top2aem2(IMPC)Tcp HOM E9.5 0.00
increased circulating alkaline phosphatase level Top2aem2(IMPC)Tcp HET Early adult 2.93×10-15
increased mean corpuscular volume Top2aem2(IMPC)Tcp HET Early adult 2.74×10-05
increased hematocrit Top2aem2(IMPC)Tcp HET Early adult 9.78×10-05
prenatal lethality prior to heart atrial septation Top2aem2(IMPC)Tcp HOM E15.5 0.00

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Eye Morphology: Images Ophthalmoscopy
164 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Eye Morphology: Images Slit Lamp
33 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Slit Lamp
3 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Top2atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Top2aem2(IMPC)Tcp Exon Deletion Mice, Tissue

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter