Gene: Top2a

Name
topoisomerase (DNA) II alpha
MGI ID
MGI:98790
Synonyms
Top-2 DNA Topoisomerase II alpha
Viability
N/A
View
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased mean corpuscular volume Top2aem2(IMPC)Tcp HET postnatal 4.55×10-05
prenatal lethality prior to heart atrial septation Top2aem2(IMPC)Tcp HOM embryonic day 14.5 0.00
embryonic lethality prior to organogenesis Top2aem2(IMPC)Tcp HOM embryonic day 9.5 0.00

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
X-ray: XRay Images Lateral Orientation
10 Images
Eye Morphology: Images Slit Lamp
3 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Top2atm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Top2aem2(IMPC)Tcp Exon Deletion Mice, Tissue

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