Spleen Immunophenotyping: Images associated with FACS analysis
WT Images
15 weeks old
Mature NK cells - % of NK cellls: 79.014
15 weeks old
Resting Treg cells - % of Treg: 58.223
15 weeks old
Conventional DC (cDC) - % of CD45+: 1.509
15 weeks old
Resting CD4- NKT cells - % of CD4- NKT cells: 65.42
15 weeks old
CD11b-low cDC - % of cDC: 44.004
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD45+: 0.16
15 weeks old
Effector gd cells - % of CD45+: 0.504
15 weeks old
Immature NK cells - % of lymphocytes: 0.621
15 weeks old
Total CD4- NKT cells - % of CD45+: 0.33
15 weeks old
CD4+ T helper cells - % of CD4+: 88.702
15 weeks old
B1a cells - % of B cells: 1.383
15 weeks old
Germinal centre B cells - % of CD45+: 0.24
15 weeks old
Marginal zone B cells - % of B2 cells: 6.071
15 weeks old
CD11b-low cDC - % of CD45+: 0.664
15 weeks old
Macrophages - % of CD45+: 0.616
15 weeks old
Effector Treg cells - % of CD45+: 0.617
15 weeks old
Effector CD8+ T cells - % of CD8+: 6.136
15 weeks old
Ly6C+ NKT cells - % of lymphocytes: 0.53
15 weeks old
Mature NK cells - % of lymphocytes: 2.337
15 weeks old
Naive CD8+ T cells - % of CD45+: 5.623
15 weeks old
Plasma cells - % of CD45+: 0.106
15 weeks old
Effector NK cells - % of CD45+: 0.361
15 weeks old
B2 t1 + t2 cells - % of B2 cells: 9.78
15 weeks old
Resting CD4+ T helper cells - % of CD4+ T helper cells: 70.523
15 weeks old
KLRG1+ Treg cells - % of CD45+: 0.131
15 weeks old
CD5+ gd T cells - % of CD45+: 0.499
15 weeks old
Effector CD4- NKT cells - % of CD4- NKT cells: 34.58
15 weeks old
CD11b-high cDC - % of CD45+: 0.84
15 weeks old
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 1.394
15 weeks old
Total ab T cells - % of CD45+: 22.716
15 weeks old
Effector CD8+ T cells - % of CD45+: 0.591
15 weeks old
Effector CD4+ T helper cells - % of CD45+: 3.361
15 weeks old
Total gd T cells - % of CD45+: 1.223
15 weeks old
Plasma cells - % of B2 cells: 0.169
15 weeks old
Resting CD4+ NKT cells - % of CD4+ NKT cells: 16.46
15 weeks old
Plasmacytoid DC - % of DC: 19.041
15 weeks old
Total CD4+ T cells - % of CD45+: 12.97
15 weeks old
Effector gd T cells - % of gd T cells: 41.226
15 weeks old
Resting CD8+ T cells - % of CD45+: 3.147
15 weeks old
Total CD8+ T cells - % of ab T cells: 42.423
15 weeks old
Effector CD4+ NKT cells - % of CD45+: 0.268
15 weeks old
Marginal zone precursor B cells - % of CD45+: 2.948
15 weeks old
CD103+ CD11b-low cDC - % of CD45+: 0.064
15 weeks old
Resting CD8+ T cells - % of CD8+: 32.653
15 weeks old
Total B2 cells - % of B cells: 98.617
15 weeks old
Resting NK cells - % of CD45+: 2.079
15 weeks old
Total CD4+ T cells - % of ab T cells: 57.099
15 weeks old
Total Treg cells - % of CD45+: 1.486
15 weeks old
Immature NK cells - % of NK cells: 20.986
15 weeks old
Ly6C+ immature NK cells - % of lymphocytes: 0.09
Mutant Images
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ NK cells - % of CD45+: 0.303
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.134
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 52.214
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 19.477
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Effector NK cells - % of CD45+: 0.165
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ NK cells - % of CD45+: 0.319
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting NK cells - % of CD45+: 0.72
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ NK cells - % of CD45+: 0.618
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total NK cells - % of CD45+: 0.789
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total ab T cells - % of CD45+: 25.634
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 18.66
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 4.613
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 54.19
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Naive CD8+ T cells - % of CD45+: 11.178
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 45.165
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 43.774
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 5.784
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Naive CD8+ T cells - % of CD45+: 6.372
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total ab T cells - % of CD45+: 34.35
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.116
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 60.318
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Plasmacytoid DC - % of DC: 12.411
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 6.087
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total NK cells - % of CD45+: 0.918
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total NK cells - % of CD45+: 0.652
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD45+: 0.087
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 46.549
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD45+: 0.107
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Effector NK cells - % of CD45+: 0.186
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 0.657
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting NK cells - % of CD45+: 1.129
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting NK cells - % of CD45+: 0.275
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ NK cells - % of CD45+: 0.2
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Naive CD8+ T cells - % of CD45+: 9.761
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 6.071
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total ab T cells - % of CD45+: 34.089
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Effector NK cells - % of CD45+: 0.199
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 1.844
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Monocytes - % of CD45+: 0.326
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD45+: 0.085
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ NK cells - % of CD45+: 0.043
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 17.799
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 52.433
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 0.598
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Monocytes - % of CD45+: 0.772
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 0.598
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total NK cells - % of CD45+: 0.438
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Plasmacytoid DC - % of CD45+: 0.404
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 0.766
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting CD8+ T cells - % of CD45+: 5.508
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting NK cells - % of CD45+: 0.454
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 47.313
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Effector NK cells - % of CD45+: 0.198
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD4+ T helper cells: 0.647
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Effector NK cells - % of CD45+: 0.119
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Naive CD8+ T cells - % of CD45+: 11.841
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Plasmacytoid DC - % of DC: 7.348
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Monocytes - % of CD45+: 0.33
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD45+: 0.086
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 10.052
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 55.498
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total NK cells - % of CD45+: 1.601
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD4+ T cells - % of ab T cells: 46.766
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Naive CD8+ T cells - % of CD45+: 11.882
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Plasmacytoid DC - % of DC: 17.242
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total NK cells - % of CD45+: 0.215
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 18.614
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ NK cells - % of CD45+: 0.273
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
KLRG1+ CD4+ T helper cells - % of CD45+: 0.092
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of CD45+: 18.059
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Naive CD8+ T cells - % of CD45+: 11.203
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total ab T cells - % of CD45+: 35.588
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 52.574
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total ab T cells - % of CD45+: 33.539
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total CD8+ T cells - % of ab T cells: 39.212
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting NK cells - % of CD45+: 0.097
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Resting NK cells - % of CD45+: 0.605
16 weeks old
Tmem127tm1(KOMP)Wtsi homozygote
Total ab T cells - % of CD45+: 35.941
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