Genes Phenotypes

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Gene: Tmem127

Name

transmembrane protein 127

MGI ID

MGI:1916720

Synonyms

2310003P10Rik

Viability

Homozygous - Viable

Embryo viewer

N/A

Other links

MGI Ensembl

Significant phenotypes (29) Measurements chart (352) All data table (969)

Expression & images (0) Disease models (0) Order (3)

Significant

Not Significant

Not tested

View body weight measurements

Phenotype	Allele	Zyg	Life Stage	P Value
increased KLRG1-positive NK cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased alpha-beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased NK cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
abnormal nail morphology	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	4.12×10^-05
increased CD4-positive, alpha beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased memory-marker NK cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased B cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased monocyte cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased effector memory CD8-positive, alpha-beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased Ly6C low monocyte number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased CD8-positive, naive alpha-beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased memory-marker NK cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased circulating bilirubin level	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	8.95×10^-05
decreased bone mineral content	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	4.98×10^-06
tremors	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	2.61×10^-06
decreased CD4-positive, alpha beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased circulating amylase level	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	4.61×10^-08
decreased KLRG1-positive T-helper cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased circulating alkaline phosphatase level	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	4.31×10^-13
increased bone mineral density	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	6.57×10^-06
decreased B-2 B cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased neutrophil cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased plasmacytoid dendritic cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased circulating creatinine level	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	7.20×10^-05
decreased Ly6C high monocyte number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
decreased KLRG1-positive NK cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
obsolete increased CD8-positive, alpha beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00
increased CD8-positive, alpha-beta T cell number	Tmem127^{tm1(KOMP)Wtsi}	HOM	Early adult	0.00

Download data as: TSV XLS

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Viewing: all phenotypes

Expression

Expression data not available

Associated Images

Mesenteric Lymph Node Immunophenotyping: Images associated with FACS analysis
49 Images

Spleen Immunophenotyping: Images associated with FACS analysis
80 Images

Ear epidermis immunophenotyping
12 Images

X-ray: XRay Images Skull Lateral Orientation
14 Images

X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images

DSS Histology
8 Images

X-ray: XRay Images Forepaw
14 Images

X-ray: XRay Images Whole Body Lateral Orientation
14 Images

X-ray: XRay Images Whole Body Dorso Ventral
14 Images

Anti-nuclear antibody assay
6 Images

Legacy Phenotype Associated Images

Tmem127^{tm1(KOMP)Wtsi}
HOM, Female, WTSI

View all 72 images

Tmem127^{tm1(KOMP)Wtsi}
short tail, tail, HOM, Male, WTSI

Tmem127^{tm1(KOMP)Wtsi}
polydactylous syndactyly, HOM, Female, WTSI

Tmem127^{tm1(KOMP)Wtsi}
polydactylous syndactyly, hindlimb, HOM, Female, WTSI

Tmem127^{tm1(KOMP)Wtsi}
abnormal cornea morphology, HOM, Female, WTSI

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MGI Allele	Allele Type	Produced
Tmem127^{tm1(KOMP)Vlcg}	Reporter-tagged deletion allele (with selection cassette)	Targeting vectors, ES Cells
Tmem127^{tm444523(L1L2_GT1_LF2A_LacZ_BetactP_neo)}		Targeting vectors
Tmem127^{tm1(KOMP)Wtsi}	Reporter-tagged deletion allele (with selection cassette)	Mice, Targeting vectors, ES Cells

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