Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; LEFT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging ; LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging ; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging ; LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging ; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; LEFT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging ; LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging ; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging ; LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging ; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; LEFT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; LEFT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging ; LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging ; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; LEFT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Some lens opacity, some lesion near optic nerve, slight hemorrhaging

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; LEFT EYE: Very slight lens opacity. Blood vessel early branching, some rd8, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight hemorrhage; RIGHT EYE: Slight lens opacity. Slight rd8

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight hemorrhaging ; LEFT EYE: Some rd8 and slight lens opacity.,
Ophthalmoscope Observation: Both eyes slight hemorrhaging ; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, slight hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; LEFT EYE: Slight lens opacity, crystallized debris, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight rd8 ; RIGHT EYE: Hyaloid present, very slight lens opacity, slight dysplasia

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some dysplasia,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Hyaloid present obstructing the optic nerve, difficult to focus and image, slight molten patches, slight hemorrhaging

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: RIGHT EYE: Some rd8, slight hemorrhage

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; RIGHT EYE: Slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8 and slight dysplasia; LEFT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; LEFT EYE: Slight lens opacity, crystallized debris present,
Ophthalmoscope Observation: Both eyes hyaloid present, some rd8, some hemorrhage; RIGHT EYE:

14 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye; LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: LEFT EYE: Slight lens opacity, some rd8,
Ophthalmoscope Observation: RIGHT EYE: No data, missing right eye

15 weeks old

L2hgdhem1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging.; RIGHT EYE:

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