Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; LEFT EYE: Lesions present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; LEFT EYE: Lesions present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Crystallized debris present.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Crystallized debris present.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; LEFT EYE: Lesions present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; LEFT EYE: Lesions present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Crystallized debris present.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; LEFT EYE: Lesions present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Crystallized debris present.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; RIGHT EYE: Hyaloid present. Abnormal white patches on retina, slight dysplasia,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; LEFT EYE: Lesions present,
Ophthalmoscope Observation: Both eyes slight lens opacity, crystallized debris present. Some rd8, some hemorrhage, some molten patches; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); RIGHT EYE: Hyaloid present and slight hemorrhaging.,
Ophthalmoscope Observation: Both eyes some rd8 and slight dysplasia. Vessel crossing (just above and below optic nerve); LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Crystallized debris present.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8 and hemorrhaging, slight lens opacity. Vessel crossing in both eyes.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes slight rd8 and hemorrhaging.; RIGHT EYE: Slight debris

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Crystallized debris present.,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE: Crystallized debris, slight dysplasia,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; RIGHT EYE: Tiny hyaloid, abnormal retinal pigmentations,
Ophthalmoscope Observation: Both eyes moderate/severe white molten/bright patches, slight lens opacity, crystallized debris, slight hemorrhage, some rd8; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, very slight hemorrhage; RIGHT EYE: Very slight lens opacity

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; LEFT EYE: Slight lens opacity (difficult to focus).,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia and hemorrhaging.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; LEFT EYE: Vessel crossing (just below optic nerve on right side). Slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8 and slight hemorrhaging.; RIGHT EYE: Hyaloid present. Some lens opacity.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; LEFT EYE: Vessel crossing (around optic nerve on left side).,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhaging and lens opacity.; RIGHT EYE: Slight dysplasia

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight dysplasia, hemorrhaging and very slight lens opacity.; RIGHT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; RIGHT EYE: Hyaloid present,
Ophthalmoscope Observation: Both eyes slight lens opacity, slight hemorrhage, some rd8 ; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; LEFT EYE: Slight dysplasia. Vessel crossing (on optic nerve).,
Ophthalmoscope Observation: Both eyes slight lens opacity. Some rd8 and slight hemorrhaging.; RIGHT EYE: Difficult to focus.

14 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE: Crystallized debris, tiny hyaloid present,
Ophthalmoscope Observation: Both eyes very slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:

15 weeks old

Smchd1em1(IMPC)Tcp heterozygote

Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8 ; RIGHT EYE: Very slight lens opacity, crystallized debris. Slight hemorrhage

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