Eye Morphology: Images Ophthalmoscopy

WT Images

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right eye, retina not clearly visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Left retina has abnormal texture, structure, colour

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: Mild opacity in right eye, retina appears normal

15 weeks old

Ophthalmoscope Observation: Patch of dysplasia in lower left retina

14 weeks old

Ophthalmoscope Observation: White mass in anterior of eye

14 weeks old

Ophthalmoscope Observation: Yellow body adjacent to optic disc

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opaque cornea in right and left eye, retina not well observed

14 weeks old

Ophthalmoscope Observation: White patch in left retina

15 weeks old

Ophthalmoscope Observation: Holes in left retina

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

14 weeks old

14 weeks old

Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8, hyaloid present; L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: some Rd8; R eye: some hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large white deposit in right retina

14 weeks old

Ophthalmoscope Observation: Bluish tint in right retina, yellow body near optic disc

15 weeks old

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: Sept 29/17 both eyes: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some Rd8,
Ophthalmoscope Observation: R eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: R eye: some hemorrhage; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

14 weeks old

Ophthalmoscope Observation: Cataract obstruction in right eye

14 weeks old

Ophthalmoscope Observation: Yellow body in left retina

15 weeks old

Ophthalmoscope Observation: Slight corneal opacity in left eye; Yellow body on left cornea

14 weeks old

15 weeks old

Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8,
Ophthalmoscope Observation: R eye: opacity on lens, branches vessels, hyaloid present; L eye: some Rd8; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: LEFT EYE:

15 weeks old

Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes,
Ophthalmoscope Observation: R eye: hyaloid present; A lot of rd8 both eyes; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Opacity in right and left eyes, retinas not very visible

15 weeks old

Ophthalmoscope Observation: Right retina bluish in colour; Yellow body in anterior of eye

14 weeks old

Ophthalmoscope Observation: Both eyes: little bit of hemorrhage,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes: little bit of hemorrhage ; RIGHT EYE:

15 weeks old

Ophthalmoscope Observation: L eye: some Rd8,
Ophthalmoscope Observation: L eye: some Rd8; LEFT EYE:,
Ophthalmoscope Observation: L eye: some Rd8; RIGHT EYE:

14 weeks old

Ophthalmoscope Observation: Large yellow body obstructing right eye

Mutant Images

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions),
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, moderate hemorrhage, white molten patches (or lesions); RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8.,
Ophthalmoscope Observation: Both eyes some rd8.; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8.; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; LEFT EYE: Some hemorrhage,
Ophthalmoscope Observation: Both eyes some crystallized debris difficult to focus, some rd8; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; LEFT EYE:,
Ophthalmoscope Observation: Both eyes some rd8, slight lens opacity ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Crystallized debris near the optic nerve difficult to focus.,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, abnormal blood vessel crossing,some hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage ; RIGHT EYE: Hyaloid present, crystallized debris present.

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; LEFT EYE: Slight lens opacity, some hemorrhage,
Ophthalmoscope Observation: Both eyes some rd8; RIGHT EYE: Slight hemorrhage

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some hemorrhage, some rd8; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, slight hemorrhage; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; RIGHT EYE: Hyaloid present, slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, some hemorrhage; LEFT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; LEFT EYE: Slight lens opacity,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage; RIGHT EYE: Hyaloid present

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; LEFT EYE: Slight lens opacity, difficult to focus,
Ophthalmoscope Observation: Both eyes some rd8, slight hemorrhage ; RIGHT EYE:

14 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; LEFT EYE:,
Ophthalmoscope Observation: Both eyes slight lens opacity, some rd8, some hemorrage; RIGHT EYE:

15 weeks old

Ptp4a2em1(IMPC)Tcp homozygote

Ophthalmoscope Observation: LEFT EYE:,
Ophthalmoscope Observation: RIGHT EYE:

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