Grip Strength: Forelimb grip strength measurement
WT Images
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
15 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.; brain - normal, There is homorrahage damage on the area of under the brain stem. due to cervical dislocation slightly.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; Inguinal lymph nodes were enlarged (1.5x3mm); lymph nodes - enlarged lymph nodes, area=1.5x3, inguinal,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; Inguinal lymph nodes were enlarged (1.5x3mm); lymph nodes - enlarged lymph nodes, area=1.5x3, inguinal,
Comments (in English): Lateral view,
Comments (in English): Internal view
15 weeks old
16 weeks old
Comments (in English): Animal was bright, alert and responsive with healthy furcoat and normal posture. There were no discharges or secretions from the nares, conjunctiva, aural, urogenital or anal openings. No significant external lesions found on the body.; The following tissues were examined: calvarium, cerebrum, cerebellum, eyes, ears, tongue, Harderian gland, Zymbal gland, salivary glands, nasal sinuses, teeth, trachea, lungs, heart, thymus, thyroid gland, spleen, liver, gall bladder, pancreas, esophagus, stomach, large and small intestines, kidneys, urinary tract, adrenal gland, reproductive organs, lymph nodes, spinal cord, bone, skeletal muscle, brown fat, and skin.; brain - normal, There is homorrahage damage on the area of under the brain stem. due to cervical dislocation slightly.,
Comments (in English): Lateral view,
Comments (in English): Internal view
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
16 weeks old
Mutant Images
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Lung: expression
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Bone: expression
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Vascular System: expression
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Vascular System: expression
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Stomach: expression
Crispld2tm1.1(KOMP)Vlcg homozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Stomach: expression
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: White spots in right and left retina
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Slit Lamp observation: Small right eye, opacity on right cornea, right eye partially closed,
Slit Lamp observation: Small right eye, opacity on right cornea, right eye partially closed; RIGHT EYE: magnification = 16x
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: White spots in right retina
Crispld2tm1.1(KOMP)Vlcg homozygote
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Slit Lamp observation: Mild opacity over right pupil,
Slit Lamp observation: Mild opacity over right pupil; RIGHT EYE: magnification = 40x
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Vascular System: expression
Crispld2tm1.1(KOMP)Vlcg homozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Pituitary gland: expression
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Esophagus: expression
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Esophagus: expression
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: Plaque beside right optic disc
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: Small white plaque in right retina
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Heart: expression
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: White plaque in right retina
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Comment on image: Compared to WT embryo on the left.
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: White substance on right vessel
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Vascular System: expression
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Trachea: expression
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
15 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Ophthalmoscope Observation: White spots in right and left retina
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Lung: expression
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Eye - MA term: MA:0000276
Crispld2tm1.1(KOMP)Vlcg homozygote
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Crispld2tm1.1(KOMP)Vlcg homozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
16 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Heart: expression
8 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
Vascular System: expression
14 weeks old
Crispld2tm1.1(KOMP)Vlcg heterozygote
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