Histopathology data for Vwa2

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM F #4 Thymus [MA:0000142]
HOM F #3 Tibia [MA:0001361]
HOM M #1 Tongue [MA:0000347]
HOM F #3 Urinary bladder [MA:0000380]
HOM F #3 Liver [MA:0000358]
HOM M #1 Epididymis [MA:0000397]
HOM M #2 Adrenal gland [MA:0000116]
HOM M #1 Brown adipose tissue [MA:0000057] 1 0 Brown adipose: Mild, regional, mixed inflammatory steatitis
HOM F #4 Stomach [MA:0000353]
HOM F #4 Bone [MA:0001459]
HOM M #1 Lung [MA:0000415]
HOM F #3 Thyroid
HOM F #4 Gall bladder [MA:0000356]
HOM F #4 Ovary [MA:0000384]
HOM F #3 Sciatic nerve [MA:0001172]
HOM F #3 Knee joint [MA:0000471]
HOM F #4 Bone marrow [MA:0000134]
HOM F #4 Heart [MA:0000072]
HOM M #2 Sciatic nerve [MA:0001172]
HOM M #2 Kidney [MA:0000368]
HOM M #2 Trachea [MA:0000441]
HOM M #2 Spleen [MA:0000141]
HOM F #4 Skin [MA:0000151]
HOM M #2 Tongue [MA:0000347]
HOM M #2 Lung [MA:0000415]
HOM M #2 Skeletal muscle [MA:0003148]
HOM F #4 Large intestine [MA:0000333]
HOM F #3 Tooth [MA:0000348]
HOM F #4 Femur [MA:0001359]
HOM F #4 Brain [MA:0000168]
HOM F #4 Spleen [MA:0000141]
HOM F #3 Salivary gland [MA:0000346]
HOM F #3 Sternum [MA:0001331]
HOM M #2 Eye [MA:0000261] 1 0 Eye: Minimal, multifocal retinal dysplasia
HOM F #3 Skeletal muscle [MA:0003148]
HOM F #3 Kidney [MA:0000368]
HOM F #4 Trachea [MA:0000441]
HOM M #2 Bone marrow [MA:0000134]
HOM M #1 Spinal cord [MA:0000216]
HOM M #2 Testis [MA:0000411]
HOM M #2 Gall bladder [MA:0000356]
HOM F #4 Pancreas [MA:0000120]
HOM M #2 Thymus [MA:0000142]
HOM F #3 Small intestine [MA:0000337]
HOM M #2 Nasal cavity [MA:0000284]
HOM M #1 Prostate gland [MA:0000404]
HOM F #3 Lung [MA:0000415]
HOM F #4 Lymph node [MA:0000139] 2 0 Lymph node, mesenteric: Moderate, paracortical and follicular lymphoid hyperplasia with sinus histiocytosis
HOM M #1 Thyroid
HOM M #1 Testis [MA:0000411] 1 0 Testis, unilateral: Multinucleated giant cells, mild increase
HOM M #1 Trachea [MA:0000441]
HOM M #2 Bone [MA:0001459]
HOM F #3 Esophagus [MA:0000352]
HOM M #2 Spinal cord [MA:0000216]
HOM M #2 Knee joint [MA:0000471]
HOM M #2 Prostate gland [MA:0000404]
HOM M #1 Femur [MA:0001359]
HOM M #1 Nasal cavity [MA:0000284]
HOM M #1 Knee joint [MA:0000471]
HOM F #4 Adrenal gland [MA:0000116]
HOM M #1 Sciatic nerve [MA:0001172]
HOM M #2 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, paracortical lymphoid hyperplasia
HOM F #4 Liver [MA:0000358]
HOM M #2 Tibia [MA:0001361]
HOM F #4 Urinary bladder [MA:0000380]
HOM F #4 Tibia [MA:0001361]
HOM M #2 Trigeminal V ganglion [MA:0001080]
HOM F #4 Kidney [MA:0000368]
HOM M #1 Gall bladder [MA:0000356]
HOM M #2 Heart [MA:0000072]
HOM M #2 Esophagus [MA:0000352]
HOM F #3 Stomach [MA:0000353]
HOM F #4 Skeletal muscle [MA:0003148]
HOM F #3 Lymph node [MA:0000139]
HOM M #2 Sternum [MA:0001331]
HOM M #2 Thyroid
HOM M #1 Sternum [MA:0001331]
HOM F #3 Brain [MA:0000168]
HOM F #4 Esophagus [MA:0000352]
HOM F #4 Salivary gland [MA:0000346]
HOM F #4 Trigeminal V ganglion [MA:0001080]
HOM F #4 Tooth [MA:0000348]
HOM M #1 Small intestine [MA:0000337]
HOM M #1 Heart [MA:0000072]
HOM M #2 Salivary gland [MA:0000346]
HOM M #2 Brown adipose tissue [MA:0000057]
HOM F #4 Sternum [MA:0001331]
HOM F #3 Spleen [MA:0000141]
HOM F #4 Spinal cord [MA:0000216]
HOM M #2 Liver [MA:0000358]
HOM F #3 Trachea [MA:0000441]
HOM M #1 Eye [MA:0000261] 1 0 Eye, bilateral: Minimal, multifocal retinal dysplasia
HOM M #1 Stomach [MA:0000353]
HOM M #1 Trigeminal V ganglion [MA:0001080]
HOM M #2 Femur [MA:0001359]
HOM F #3 Femur [MA:0001359]
HOM M #1 Thymus [MA:0000142]
HOM M #1 Ear [MA:0000236]
HOM M #1 Pancreas [MA:0000120]
HOM M #1 Esophagus [MA:0000352]
HOM F #4 Small intestine [MA:0000337]
HOM F #3 Nasal cavity [MA:0000284] 2 0 Nasal cavity: Moderate, lateral septal deviation
HOM M #2 Small intestine [MA:0000337]
HOM F #3 Bone [MA:0001459]
HOM M #1 Skin [MA:0000151]
HOM F #3 Gall bladder [MA:0000356]
HOM M #2 Brain [MA:0000168]
HOM M #2 Stomach [MA:0000353]
HOM M #1 Bone marrow [MA:0000134]
HOM F #3 Thymus [MA:0000142]
HOM M #2 Seminal vesicle [MA:0000410]
HOM F #3 Trigeminal V ganglion [MA:0001080]
HOM F #3 Adrenal gland [MA:0000116]
HOM M #2 Urinary bladder [MA:0000380]
HOM F #3 Ovary [MA:0000384]
HOM M #2 Epididymis [MA:0000397]
HOM M #1 Brain [MA:0000168]
HOM F #4 Tongue [MA:0000347]
HOM F #4 Lung [MA:0000415]
HOM F #4 Knee joint [MA:0000471]
HOM M #2 Skin [MA:0000151]
HOM M #1 Lymph node [MA:0000139]
HOM M #2 Tooth [MA:0000348]
HOM M #2 Pancreas [MA:0000120]
HOM M #1 Large intestine [MA:0000333]
HOM F #4 Sciatic nerve [MA:0001172]
HOM M #1 Urinary bladder [MA:0000380]
HOM F #3 Eye [MA:0000261] 1 0 Eye: Mild, multifocal retinal dysplasia
HOM F #3 Tongue [MA:0000347]
HOM F #3 Ear [MA:0000236]
HOM M #1 Spleen [MA:0000141]
HOM F #4 Uterus [MA:0000389]
HOM M #1 Tooth [MA:0000348]
HOM F #4 Mammary gland [MA:0000145]
HOM F #3 Brown adipose tissue [MA:0000057]
HOM F #3 Pancreas [MA:0000120]
HOM M #2 Ear [MA:0000236]
HOM M #2 Large intestine [MA:0000333]
HOM M #1 Salivary gland [MA:0000346]
HOM M #1 Seminal vesicle [MA:0000410]
HOM F #4 Ear [MA:0000236]
HOM M #1 Bone [MA:0001459]
HOM F #4 Thyroid
HOM F #4 Eye [MA:0000261]
HOM M #1 Skeletal muscle [MA:0003148]
HOM F #4 Brown adipose tissue [MA:0000057]
HOM M #1 Adrenal gland [MA:0000116]
HOM M #1 Kidney [MA:0000368]
HOM F #4 Nasal cavity [MA:0000284]
HOM F #3 Skin [MA:0000151]
HOM M #1 Tibia [MA:0001361]
HOM M #1 Liver [MA:0000358]
HOM F #3 Heart [MA:0000072]
HOM F #3 Bone marrow [MA:0000134]
HOM F #3 Large intestine [MA:0000333]
HOM F #3 Uterus [MA:0000389]
HOM F #3 Mammary gland [MA:0000145]
HOM F #3 Spinal cord [MA:0000216]

Associated histopathology images

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