Histopathology data for Sra1

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #4 Stomach [MA:0000353] 0 0
HOM F #1 Skeletal muscle [MA:0003148] 0 0
HOM M #4 Skeletal muscle [MA:0003148] normal [MPATH:458]
HOM M #2 Pancreas [MA:0000120] inflammation [MPATH:212] steatitis MPATH:636 focally extensive
HOM F #1 Skin [MA:0000151] 0 0
HOM M #4 Brain [MA:0000168] process of degenerative change [MPATH:14] bilateral
HOM F #3 Eye with optic nerve 0 0
HOM F #1 Liver [MA:0000358] normal [MPATH:458]
HOM F #3 Eye with optic nerve normal [MPATH:458]
HOM M #4 Lung [MA:0000415] 0 0
HOM M #4 Brain [MA:0000168] 1 0 Bilateral and mild dilation of the lateral ventricles
HOM M #2 Small intestine [MA:0000337] 0 0
HOM M #4 Skin [MA:0000151] normal [MPATH:458]
HOM F #1 Uterus [MA:0000389] 0 0
HOM M #2 Liver [MA:0000358] 0 0
HOM F #3 Pancreas [MA:0000120] 0 0
HOM M #2 Spinal cord [MA:0000216] normal [MPATH:458]
HOM F #1 Kidney [MA:0000368] normal [MPATH:458]
HOM F #3 Liver [MA:0000358] normal [MPATH:458]
HOM F #1 Large intestine [MA:0000333] 0 0
HOM M #2 Adrenal gland [MA:0000116] 0 0
HOM M #4 Stomach [MA:0000353] normal [MPATH:458]
HOM F #1 Large intestine [MA:0000333] normal [MPATH:458]
HOM M #4 Spleen [MA:0000141] 0 0
HOM F #1 Thyroid 0 0
HOM M #4 Kidney [MA:0000368] 0 0
HOM M #4 Heart [MA:0000072] 0 0
HOM M #2 Testes normal [MPATH:458]
HOM M #2 Trachea [MA:0000441] normal [MPATH:458]
HOM F #3 Thyroid 0 0
HOM F #1 Eye with optic nerve 0 0
HOM F #1 Adrenal gland [MA:0000116] 0 0
HOM F #1 Urinary bladder [MA:0000380] 0 0
HOM M #2 Large intestine [MA:0000333] 0 0
HOM M #4 Trachea [MA:0000441] 0 0
HOM M #4 Small intestine [MA:0000337] normal [MPATH:458]
HOM F #3 Uterus [MA:0000389] 0 0
HOM M #2 Thyroid normal [MPATH:458]
HOM F #3 Mammary gland [MA:0000145] normal [MPATH:458]
HOM M #2 Urinary bladder [MA:0000380] 0 0
HOM M #4 Thyroid normal [MPATH:458]
HOM M #2 Small intestine [MA:0000337] normal [MPATH:458]
HOM M #4 Gall bladder [MA:0000356] 0 0
HOM F #3 Large intestine [MA:0000333] normal [MPATH:458]
HOM M #4 Esophagus [MA:0000352] normal [MPATH:458]
HOM M #2 Thymus [MA:0000142] normal [MPATH:458]
HOM F #3 Trachea [MA:0000441] normal [MPATH:458]
HOM M #4 Epididymis [MA:0000397] 0 0
HOM M #4 Testes 0 0
HOM M #4 Prostate 0 0
HOM M #2 Seminal vesicle [MA:0000410] 0 0
HOM F #3 Ovary [MA:0000384] normal [MPATH:458]
HOM F #3 Adrenal gland [MA:0000116] 0 0
HOM M #2 Lymph node [MA:0000139] 0 0
HOM F #3 Adrenal gland [MA:0000116] normal [MPATH:458]
HOM M #2 Skeletal muscle [MA:0003148] normal [MPATH:458]
HOM M #2 Trachea [MA:0000441] 0 0
HOM F #3 Urinary bladder [MA:0000380] 0 0
HOM F #3 Kidney [MA:0000368] 0 0
HOM F #1 Liver [MA:0000358] 0 0
HOM F #1 Mammary gland [MA:0000145] 0 0
HOM F #1 Trachea [MA:0000441] normal [MPATH:458]
HOM M #2 Skin [MA:0000151] normal [MPATH:458]
HOM F #1 Urinary bladder [MA:0000380] normal [MPATH:458]
HOM F #3 Spinal cord [MA:0000216] 0 0
HOM F #1 Spinal cord [MA:0000216] 0 0
HOM F #3 Thymus [MA:0000142] normal [MPATH:458]
HOM M #2 Lung [MA:0000415] 0 0
HOM M #4 Spleen [MA:0000141] normal [MPATH:458]
HOM F #1 Pancreas [MA:0000120] 0 0
HOM M #2 Lung [MA:0000415] normal [MPATH:458]
HOM M #4 Seminal vesicle [MA:0000410] normal [MPATH:458]
HOM F #1 Mammary gland [MA:0000145] normal [MPATH:458]
HOM F #3 Lymph node [MA:0000139] normal [MPATH:458]
HOM F #1 Pancreas [MA:0000120] normal [MPATH:458]
HOM F #1 Gall bladder [MA:0000356] normal [MPATH:458]
HOM M #4 Liver [MA:0000358] 0 0
HOM M #4 Lymph node [MA:0000139] 0 0
HOM M #2 Spleen [MA:0000141] 2 0 Lymphoid hyperplasia
HOM F #3 Kidney [MA:0000368] normal [MPATH:458]
HOM F #1 Thymus [MA:0000142] normal [MPATH:458]
HOM M #2 Stomach [MA:0000353] 0 0
HOM M #4 Heart [MA:0000072] normal [MPATH:458]
HOM F #1 Lymph node [MA:0000139] normal [MPATH:458]
HOM F #3 Heart [MA:0000072] 0 0
HOM F #3 Liver [MA:0000358] 0 0
HOM F #3 Mammary gland [MA:0000145] 0 0
HOM M #2 Thymus [MA:0000142] 0 0
HOM F #1 Adrenal gland [MA:0000116] normal [MPATH:458]
HOM M #4 Urinary bladder [MA:0000380] 0 0
HOM M #2 Skeletal muscle [MA:0003148] 0 0
HOM F #1 Eye with optic nerve normal [MPATH:458]
HOM M #2 Stomach [MA:0000353] normal [MPATH:458]
HOM M #2 Seminal vesicle [MA:0000410] normal [MPATH:458]
HOM M #2 Skin [MA:0000151] 0 0
HOM M #4 Lung [MA:0000415] normal [MPATH:458]
HOM M #4 Esophagus [MA:0000352] 0 0
HOM M #4 Seminal vesicle [MA:0000410] 0 0
HOM M #2 Adrenal gland [MA:0000116] normal [MPATH:458]
HOM F #1 Esophagus [MA:0000352] 0 0
HOM F #3 Skin [MA:0000151] normal [MPATH:458]
HOM F #1 Heart [MA:0000072] 0 0
HOM F #3 Skeletal muscle [MA:0003148] normal [MPATH:458]
HOM M #4 Large intestine [MA:0000333] 0 0
HOM M #2 Epididymis [MA:0000397] normal [MPATH:458]
HOM F #3 Brain [MA:0000168] normal [MPATH:458]
HOM M #4 Eye with optic nerve normal [MPATH:458]
HOM M #4 Liver [MA:0000358] normal [MPATH:458]
HOM M #4 Adrenal gland [MA:0000116] 0 0
HOM F #1 Thyroid normal [MPATH:458]
HOM F #1 Skeletal muscle [MA:0003148] normal [MPATH:458]
HOM F #1 Skin [MA:0000151] normal [MPATH:458]
HOM M #2 Kidney [MA:0000368] 0 0
HOM F #1 Gall bladder [MA:0000356] 0 0
HOM F #3 Uterus [MA:0000389] normal [MPATH:458]
HOM F #3 Stomach [MA:0000353] normal [MPATH:458]
HOM F #3 Gall bladder [MA:0000356] 0 0
HOM F #1 Small intestine [MA:0000337] normal [MPATH:458]
HOM M #4 Spinal cord [MA:0000216] 0 0
HOM F #3 Small intestine [MA:0000337] 0 0
HOM F #1 Ovary [MA:0000384] 0 0
HOM M #2 Heart [MA:0000072] normal [MPATH:458]
HOM F #1 Kidney [MA:0000368] 0 0
HOM M #2 Kidney [MA:0000368] normal [MPATH:458]
HOM F #1 Spleen [MA:0000141] 0 0
HOM M #4 Kidney [MA:0000368] normal [MPATH:458]
HOM F #1 Uterus [MA:0000389] normal [MPATH:458]
HOM M #4 Spinal cord [MA:0000216] normal [MPATH:458]
HOM F #3 Esophagus [MA:0000352] 0 0
HOM M #4 Thyroid 0 0
HOM F #1 Stomach [MA:0000353] normal [MPATH:458]
HOM F #3 Lymph node [MA:0000139] 0 0
HOM M #4 Skin [MA:0000151] 0 0
HOM M #2 Liver [MA:0000358] normal [MPATH:458]
HOM M #2 Spleen [MA:0000141] hyperplasia [MPATH:134] lymphoid hyperplasia MPATH:147 multifocal to coalescing
HOM M #4 Thymus [MA:0000142] 1 0 Thymic cyst
HOM M #4 Skeletal muscle [MA:0003148] 0 0
HOM F #1 Lymph node [MA:0000139] 0 0
HOM F #3 Lung [MA:0000415] normal [MPATH:458]
HOM M #2 Lymph node [MA:0000139] normal [MPATH:458]
HOM F #1 Brain [MA:0000168] normal [MPATH:458]
HOM F #1 Brain [MA:0000168] 0 0
HOM M #2 Esophagus [MA:0000352] 0 0
HOM F #1 Esophagus [MA:0000352] normal [MPATH:458]
HOM F #3 Brain [MA:0000168] 0 0
HOM F #1 Spleen [MA:0000141] normal [MPATH:458]
HOM F #3 Ovary [MA:0000384] 0 0
HOM M #4 Adrenal gland [MA:0000116] normal [MPATH:458]
HOM M #4 Pancreas [MA:0000120] 0 0
HOM F #1 Small intestine [MA:0000337] 0 0
HOM M #4 Pancreas [MA:0000120] normal [MPATH:458]
HOM F #1 Spinal cord [MA:0000216] normal [MPATH:458]
HOM M #4 Lymph node [MA:0000139] normal [MPATH:458]
HOM F #3 Spleen [MA:0000141] 0 0
HOM M #2 Brain [MA:0000168] normal [MPATH:458]
HOM F #1 Heart [MA:0000072] normal [MPATH:458]
HOM F #3 Gall bladder [MA:0000356] normal [MPATH:458]
HOM M #4 Epididymis [MA:0000397] normal [MPATH:458]
HOM M #2 Eye with optic nerve normal [MPATH:458]
HOM F #1 Thymus [MA:0000142] 0 0
HOM F #3 Spleen [MA:0000141] normal [MPATH:458]
HOM F #1 Ovary [MA:0000384] normal [MPATH:458]
HOM F #3 Pancreas [MA:0000120] normal [MPATH:458]
HOM M #2 Brain [MA:0000168] 0 0
HOM M #2 Heart [MA:0000072] 0 0
HOM F #3 Urinary bladder [MA:0000380] normal [MPATH:458]
HOM M #4 Thymus [MA:0000142] developmental and structural abnormality [MPATH:55] cyst MPATH:62 localized
HOM M #4 Gall bladder [MA:0000356] normal [MPATH:458]
HOM M #4 Eye with optic nerve 0 0
HOM F #3 Large intestine [MA:0000333] 0 0
HOM M #2 Prostate normal [MPATH:458]
HOM M #4 Large intestine [MA:0000333] normal [MPATH:458]
HOM F #3 Heart [MA:0000072] normal [MPATH:458]
HOM M #4 Urinary bladder [MA:0000380] normal [MPATH:458]
HOM F #3 Skin [MA:0000151] 0 0
HOM F #3 Skeletal muscle [MA:0003148] 0 0
HOM F #3 Thyroid normal [MPATH:458]
HOM F #3 Small intestine [MA:0000337] normal [MPATH:458]
HOM F #3 Esophagus [MA:0000352] normal [MPATH:458]
HOM F #1 Lung [MA:0000415] normal [MPATH:458]
HOM M #2 Prostate 0 0
HOM M #2 Esophagus [MA:0000352] normal [MPATH:458]
HOM M #2 Eye with optic nerve 0 0
HOM F #3 Thymus [MA:0000142] 0 0
HOM M #2 Gall bladder [MA:0000356] normal [MPATH:458]
HOM F #3 Stomach [MA:0000353] 0 0
HOM M #4 Small intestine [MA:0000337] 0 0
HOM F #3 Spinal cord [MA:0000216] normal [MPATH:458]
HOM F #1 Trachea [MA:0000441] 0 0
HOM M #2 Testes 0 0
HOM M #2 Thyroid 0 0
HOM M #2 Large intestine [MA:0000333] normal [MPATH:458]
HOM M #2 Gall bladder [MA:0000356] 0 0
HOM M #4 Prostate normal [MPATH:458]
HOM M #4 Trachea [MA:0000441] normal [MPATH:458]
HOM M #2 Spinal cord [MA:0000216] 0 0
HOM F #3 Lung [MA:0000415] 0 0
HOM M #4 Testes normal [MPATH:458]
HOM F #1 Lung [MA:0000415] 0 0
HOM M #2 Urinary bladder [MA:0000380] normal [MPATH:458]
HOM F #3 Trachea [MA:0000441] 0 0
HOM M #2 Epididymis [MA:0000397] 0 0
HOM M #2 Pancreas [MA:0000120] 1 0 Peripancreatic focally extensive steatitis
HOM F #1 Stomach [MA:0000353] 0 0

Associated histopathology images

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