Histopathology data for Slc22a29

Score Definitions

Severity Score:

  • 0 = Normal,
  • 1 = Mild (observation barely perceptible and not believed to have clinical significance),
  • 2 = Moderate (observation visible but involves minor proportion of tissue and clinical consequences of observation are most likely subclinical),
  • 3 = Marked (observation clearly visible involves a significant proportion of tissue and is likely to have some clinical manifestations generally expected to be minor),
  • 4 = Severe (observation clearly visible involves a major proportion of tissue and clinical manifestations are likely associated with significant tissue dysfunction or damage)

Significance Score:

  • 0 = Not significant: Interpreted by the histopathologist to be a finding attributable to background strain (e.g. low-incidence hydrocephalus, microphthalmia) or incidental to mutant phenotype (e.g. hair-induced glossitis, focal hyperplasia, mild mononuclear cell infiltrate).
  • 1 = Significant: Interpreted by the histopathologist as a finding not attributable to background strain and not incidental to mutant phenotype.


Zyg Sex Mouse Tissue MPATH Process Term Severity Score Significance Score MPATH Diagnostic PATO Descriptor Free Text Images
HOM M #1 Heart [MA:0000072]
HOM M #1 Brain [MA:0000168]
HOM F #2 Uterus [MA:0000389]
HOM F #2 Brain [MA:0000168]
HOM F #2 Heart [MA:0000072]
HOM M #1 Ear [MA:0000236]
HOM F #2 Lung [MA:0000415]
HOM F #2 Bone marrow [MA:0000134]
HOM F #2 Esophagus [MA:0000352]
HOM M #1 Esophagus [MA:0000352]
HOM M #1 Lung [MA:0000415]
HOM F #4 Small intestine [MA:0000337]
HOM M #1 Skeletal muscle [MA:0003148]
HOM F #2 Skeletal muscle [MA:0003148]
HOM M #1 Bone marrow [MA:0000134]
HOM M #1 Tongue [MA:0000347]
HOM F #2 Tongue [MA:0000347]
HOM M #3 Small intestine [MA:0000337]
HOM F #2 Sciatic nerve [MA:0001172]
HOM F #2 Skin [MA:0000151]
HOM M #1 Skin [MA:0000151]
HOM M #1 Large intestine [MA:0000333]
HOM M #3 Liver [MA:0000358]
HOM M #3 Tibia [MA:0001361]
HOM M #1 Spleen [MA:0000141] 1 0 Spleen: Extramedullary hematopoiesis, mild increase
HOM F #2 Large intestine [MA:0000333]
HOM F #4 Tibia [MA:0001361]
HOM M #3 Adrenal gland [MA:0000116]
HOM F #4 Liver [MA:0000358]
HOM F #4 Adrenal gland [MA:0000116]
HOM F #2 Thyroid
HOM F #2 Gall bladder [MA:0000356]
HOM F #4 Kidney [MA:0000368]
HOM F #2 Spleen [MA:0000141] 2 0 Spleen: Moderate, lymphofollicular hyperplasia with mild increase in extramedullary hematopoiesis and generalized congestion
HOM F #2 Ear [MA:0000236]
HOM M #3 Kidney [MA:0000368]
HOM F #2 Ovary [MA:0000384]
HOM F #4 Large intestine [MA:0000333]
HOM F #2 Salivary gland [MA:0000346]
HOM F #2 Adrenal gland [MA:0000116]
HOM F #2 Bone [MA:0001459]
HOM M #1 Gall bladder [MA:0000356]
HOM M #1 Thyroid
HOM M #3 Testis [MA:0000411]
HOM M #3 Prostate gland [MA:0000404]
HOM F #4 Urinary bladder [MA:0000380]
HOM M #1 Femur [MA:0001359]
HOM F #4 Salivary gland [MA:0000346]
HOM F #2 Kidney [MA:0000368]
HOM M #3 Urinary bladder [MA:0000380]
HOM M #1 Epididymis [MA:0000397]
HOM M #3 Brain [MA:0000168]
HOM M #3 Salivary gland [MA:0000346]
HOM M #3 Ear [MA:0000236]
HOM M #3 Large intestine [MA:0000333]
HOM F #4 Ear [MA:0000236]
HOM M #1 Eye [MA:0000261] 1 0 Eye: Mild, multifocal retinal dysplasia
HOM F #2 Lymph node [MA:0000139] 1 0 Lymph node, mesenteric: Mild, follicular lymphoid hyperplasia
HOM F #4 Uterus [MA:0000389]
HOM M #1 Nasal cavity [MA:0000284]
HOM M #1 Sternum [MA:0001331]
HOM M #3 Bone [MA:0001459]
HOM M #1 Stomach [MA:0000353]
HOM M #1 Spinal cord [MA:0000216]
HOM F #4 Bone [MA:0001459]
HOM M #1 Trachea [MA:0000441]
HOM M #3 Esophagus [MA:0000352]
HOM M #3 Bone marrow [MA:0000134]
HOM M #1 Tooth [MA:0000348]
HOM M #1 Knee joint [MA:0000471]
HOM M #3 Seminal vesicle [MA:0000410]
HOM M #3 Brown adipose tissue [MA:0000057]
HOM F #4 Ovary [MA:0000384]
HOM F #2 Urinary bladder [MA:0000380]
HOM F #4 Bone marrow [MA:0000134]
HOM F #4 Sciatic nerve [MA:0001172]
HOM F #4 Brown adipose tissue [MA:0000057]
HOM F #2 Tibia [MA:0001361]
HOM M #3 Eye [MA:0000261]
HOM F #2 Mammary gland [MA:0000145]
HOM M #3 Sciatic nerve [MA:0001172]
HOM F #2 Liver [MA:0000358]
HOM M #1 Liver [MA:0000358]
HOM F #2 Small intestine [MA:0000337]
HOM F #4 Nasal cavity [MA:0000284]
HOM M #3 Trachea [MA:0000441]
HOM F #4 Esophagus [MA:0000352]
HOM M #1 Tibia [MA:0001361]
HOM M #3 Lymph node [MA:0000139]
HOM M #1 Thymus [MA:0000142]
HOM F #2 Thymus [MA:0000142]
HOM M #3 Nasal cavity [MA:0000284]
HOM M #1 Brown adipose tissue [MA:0000057]
HOM M #1 Pancreas [MA:0000120]
HOM M #3 Gall bladder [MA:0000356]
HOM M #3 Thyroid
HOM F #2 Pancreas [MA:0000120]
HOM F #2 Brown adipose tissue [MA:0000057]
HOM F #4 Brain [MA:0000168]
HOM F #4 Tongue [MA:0000347]
HOM F #4 Heart [MA:0000072]
HOM M #1 Trigeminal V ganglion [MA:0001080]
HOM M #3 Lung [MA:0000415]
HOM F #4 Trachea [MA:0000441]
HOM F #4 Stomach [MA:0000353]
HOM F #4 Lung [MA:0000415]
HOM F #2 Trigeminal V ganglion [MA:0001080]
HOM M #3 Tongue [MA:0000347]
HOM F #4 Lymph node [MA:0000139] 2 0 Lymph node, mesenteric: Moderate, paracortical and follicular lymphoid hyperplasia with sinus histiocytosis
HOM M #3 Heart [MA:0000072]
HOM F #4 Spleen [MA:0000141] 2 0 Spleen: Moderate, lymphofollicular hyperplasia
HOM F #4 Sternum [MA:0001331]
HOM F #4 Trigeminal V ganglion [MA:0001080]
HOM M #1 Bone [MA:0001459]
HOM M #3 Spleen [MA:0000141]
HOM M #3 Stomach [MA:0000353]
HOM M #1 Seminal vesicle [MA:0000410]
HOM M #1 Adrenal gland [MA:0000116]
HOM F #2 Femur [MA:0001359]
HOM M #3 Tooth [MA:0000348]
HOM F #2 Sternum [MA:0001331]
HOM F #4 Knee joint [MA:0000471]
HOM M #1 Kidney [MA:0000368]
HOM M #1 Lymph node [MA:0000139] 1 0 Lymph node, mandibular: Mild, paracortical lymphoid hyperplasia Lymph node, mesenteric: Moderate, paracortical and follicular lymphoid hyperplasia with sinus histiocytosis
HOM M #3 Trigeminal V ganglion [MA:0001080]
HOM M #3 Knee joint [MA:0000471]
HOM F #4 Tooth [MA:0000348]
HOM M #1 Sciatic nerve [MA:0001172]
HOM F #2 Eye [MA:0000261]
HOM F #2 Stomach [MA:0000353]
HOM F #2 Spinal cord [MA:0000216]
HOM M #3 Skin [MA:0000151]
HOM M #3 Thymus [MA:0000142]
HOM F #2 Nasal cavity [MA:0000284]
HOM M #1 Testis [MA:0000411]
HOM F #4 Gall bladder [MA:0000356]
HOM M #3 Skeletal muscle [MA:0003148]
HOM F #4 Mammary gland [MA:0000145]
HOM F #4 Thymus [MA:0000142]
HOM F #4 Thyroid
HOM F #2 Trachea [MA:0000441]
HOM F #4 Skeletal muscle [MA:0003148]
HOM F #4 Spinal cord [MA:0000216]
HOM F #4 Pancreas [MA:0000120]
HOM F #4 Femur [MA:0001359]
HOM M #1 Small intestine [MA:0000337]
HOM M #1 Salivary gland [MA:0000346]
HOM F #2 Knee joint [MA:0000471]
HOM F #4 Eye [MA:0000261]
HOM F #2 Tooth [MA:0000348]
HOM M #3 Spinal cord [MA:0000216]
HOM M #3 Pancreas [MA:0000120]
HOM M #3 Epididymis [MA:0000397]
HOM M #1 Prostate gland [MA:0000404]
HOM F #4 Skin [MA:0000151]
HOM M #3 Femur [MA:0001359]
HOM M #3 Sternum [MA:0001331]
HOM M #1 Urinary bladder [MA:0000380]

Associated histopathology images

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