Gene: Ldlr

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Name
low density lipoprotein receptor
MGI ID
MGI:96765
Synonyms
N/A
Embryo Screen
N/A
Other links
Expression & images (0) Disease models (0) Order (4)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased circulating unsaturated transferrin level Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 1.40×10-08
increased mean corpuscular volume Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 7.75×10-05
increased circulating cholesterol level Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 1.73×10-10
increased circulating iron level Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 1.15×10-08
increased grip strength Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 1.86×10-06
increased circulating HDL cholesterol level Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 3.64×10-24
abnormal gait Ldlrtm1b(EUCOMM)Wtsi HOM postnatal 4.15×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Lateral Orientation
7 Images
X-ray: XRay Images Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Ldlrtm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ldlrtm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Ldlrtm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Ldlrtm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells