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Gene: Hal MGI:96010

Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:

histidine ammonia lyase

Synonyms:

Hsd, histidase

Order Alleles

IMPC Data Collections

No Body Weight Data
No Embryo Imaging Data
No Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hal mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Hal (2 diseases)
Human diseases predicted to be associated with Hal (197 diseases)

The table below shows human diseases associated to Hal by orthology or direct annotation.

Disease	Similarity of phenotypes	Matching phenotypes	Source
Histidinemia		Hyperhistidinemia, Histidinuria	OMIM:235800
Histidinemia		Hyperhistidinemia, Histidinuria	ORPHA:2157

The table below shows human diseases predicted to be associated to Hal by phenotypic similarity.

Disease	Matching phenotypes	Source
Indolylacroyl Glycinuria With Mental Retardation	Hyperglycinuria	OMIM:243050
Iminoglycinuria	Prolinuria, Hydroxyprolinuria, Hyperglycinuria	OMIM:242600
Iminoglycinuria	Prolinuria, Hydroxyprolinuria, Hyperglycinuria	ORPHA:42062
Beta-Aminoisobutyric Aciduria	Beta-aminoisobutyric aciduria	OMIM:210100
Cystathioninuria	Cystathioninuria	OMIM:219500
Phenylketonuria	Aminoaciduria	ORPHA:716
Dibasic Amino Aciduria I	Argininuria, Dibasicaminoaciduria, Hyperlysinuria, Ornithinuria	OMIM:222690
Uridine-Cytidineuria	Elevated urinary cytidine, Elevated uridine in urine	OMIM:618477
Methylmalonic Aciduria, Transient, Due To Transcobalamin Receptor Defect	Methylmalonic aciduria	OMIM:613646
Sedoheptulokinase Deficiency	Increased urinary sedoheptulose	OMIM:617213
Lysine Malabsorption Syndrome	Hyperlysinuria, Renal tubular lysine transport defect	OMIM:247950
Seizures-Intellectual Disability Due To Hydroxylysinuria Syndrome	Aminoaciduria	ORPHA:79156
Hyperprolinemia, Type Ii	Prolinuria, Hydroxyprolinuria, Hyperglycinuria	OMIM:239510
Carnosinemia	Carnosinuria	OMIM:212200
Hydroxylysinuria	Hyperlysinuria	OMIM:236900
Cystinuria	Ornithinuria, Nephrolithiasis, Cystinuria, Recurrent urinary tract infections, Argininuria, Hyper...	OMIM:220100
Hyperglycinuria	Hyperglycinuria, Calcium oxalate nephrolithiasis	OMIM:138500
Glucoglycinuria	Hyperglycinuria, Glycosuria	OMIM:138070
Camptodactyly-Taurinuria Syndrome	Aminoaciduria, Increased urinary taurine	ORPHA:1325
Pentosuria	Abnormality of urine homeostasis	OMIM:260800
Dicarboxylic Aminoaciduria	Aminoaciduria, Nephrolithiasis, Aspartic aciduria	OMIM:222730
Tiglic Acidemia	Aminoaciduria	OMIM:275190
Saccharopinuria	Citrullinuria, Saccharopinuria, Hyperlysinuria, Histidinuria	OMIM:268700
Hyperprolinemia Type 1	Prolinuria, Proteinuria, Nephropathy	ORPHA:419
Ichthyosis, Split Hairs, And Amino Aciduria	Aminoaciduria	OMIM:242550
Carnosinase Deficiency	Carnosinuria	ORPHA:1361
Threoninemia	Hyperthreoninuria	OMIM:273770
Camptodactyly 1	Increased urinary taurine	OMIM:114200
Diaminopentanuria	Hyperlysinuria, Cystinuria	OMIM:222350
Alpha-Aminoadipic And Alpha-Ketoadipic Aciduria	Alpha-aminoadipic aciduria	OMIM:204750
Proteinuria, Low Molecular Weight, With Hypercalciuria And Nephrocalcinosis	Renal tubular atrophy, Focal segmental glomerulosclerosis, Nephrocalcinosis, Proximal tubulopathy...	OMIM:308990
Cerebral Creatine Deficiency Syndrome 3	Organic aciduria	OMIM:612718
Homocarnosinosis	Carnosinuria	OMIM:236130
Hyperoxaluria, Primary, Type Ii	Calcium oxalate nephrolithiasis, Nephrocalcinosis, Hyperoxaluria, Hematuria, Aminoaciduria, Renal...	OMIM:260000
Histidinemia	Hyperhistidinemia, Histidinuria	OMIM:235800
5-Oxoprolinase Deficiency	Prolinuria, Increased level of L-pyroglutamic acid in urine, Calcium oxalate nephrolithiasis	OMIM:260005
Hyper-Beta-Alaninemia	Increased urinary taurine	OMIM:237400
Amino Aciduria With Mental Deficiency, Dwarfism, Muscular Dystrophy, Osteoporosis, And Acidosis	Aminoaciduria	OMIM:204730
Hyperprolinemia, Type I	Prolinuria, Hydroxyprolinuria, Hyperglycinuria	OMIM:239500
Glutamate Formiminotransferase Deficiency	Aminoaciduria	OMIM:229100
Nephrotic Syndrome, Type 16	Hematuria, Proteinuria, Nephrotic syndrome	OMIM:617783
Mercaptolactate-Cysteine Disulfiduria	Aminoaciduria	OMIM:249650
Ichthyosis-Intellectual Disability-Dwarfism-Renal Impairment Syndrome	Aminoaciduria	ORPHA:2278
Macular Dystrophy, Retinal, 1, North Carolina Type	Generalized aminoaciduria	OMIM:136550
Fanconi Renotubular Syndrome 3	Hyperphosphaturia, Aminoaciduria, Proteinuria, Glycosuria	OMIM:615605
Valinemia	Valinuria	OMIM:277100
Muscular Dystrophy, Cardiac Type	Carnosinuria	OMIM:309930
Hyperlysinuria With Hyperammonemia	Hyperlysinuria, Dibasicaminoaciduria	OMIM:238750
Cystathioninuria	Cystathioninuria, Nephrolithiasis	ORPHA:212
Histidinemia	Hyperhistidinemia, Histidinuria	ORPHA:2157
Galactosemia Iii	Aminoaciduria, Galactosuria	OMIM:230350
Hydroxykynureninuria	Aminoaciduria, Renal tubular dysfunction	OMIM:236800
Hartnup Disorder	Neutral hyperaminoaciduria	OMIM:234500
Stimmler Syndrome	Aminoaciduria	ORPHA:3199
Tyrosinemia Type 1	Generalized aminoaciduria	ORPHA:882
Gracile Syndrome	Aminoaciduria	OMIM:603358
Proteinuria, Chronic Benign	Albuminuria, Proteinuria	OMIM:618884
Homocystinuria Due To Deficiency Of N(5,10)-Methylenetetrahydrofolate Reductase Activity	Homocystinuria	OMIM:236250
Homozygous 11P15-P14 Deletion Syndrome	Generalized aminoaciduria, Renal tubular dysfunction	OMIM:606528
Dent Disease 2	Nephrocalcinosis, Proximal tubulopathy, Low-molecular-weight proteinuria, Chronic kidney disease,...	OMIM:300555
3-Hydroxyisobutyric Aciduria	Aminoaciduria	OMIM:236795
Fanconi Renotubular Syndrome 2	Generalized aminoaciduria, Proximal tubulopathy, Glycosuria, Hypercalciuria, Renal insufficiency	OMIM:613388
Fanconi Renotubular Syndrome 1	Renal tubular dysfunction, Lacticaciduria, Glycosuria, Aminoaciduria, Proteinuria, Renal insuffic...	OMIM:134600
Carbamoyl-Phosphate Synthetase 1 Deficiency	Aminoaciduria	ORPHA:147
Argininemia	Diaminoaciduria	ORPHA:90
Alaninuria With Microcephaly, Dwarfism, Enamel Hypoplasia, And Diabetes Mellitus	Alaninuria	OMIM:202900
Combined Oxidative Phosphorylation Deficiency 36	Aciduria	OMIM:617950
Neonatal Severe Primary Hyperparathyroidism	Aminoaciduria	ORPHA:417
Histidinuria Due To A Renal Tubular Defect	Histidinuria, Impaired histidine renal tubular absorption	OMIM:235830
Methionine Malabsorption Syndrome	Aminoaciduria	OMIM:250900
Histidinuria-Renal Tubular Defect Syndrome	Histidinuria, Impaired histidine renal tubular absorption	ORPHA:2158
Mitochondrial Dna Depletion Syndrome 8A (Encephalomyopathic Type With Renal Tubulopathy)	Proximal tubulopathy, Aminoaciduria	OMIM:612075
Galactose Epimerase Deficiency	Aminoaciduria	ORPHA:79238
Dimethylglycine Dehydrogenase Deficiency	Elevated urinary N,N-dimethylglycine level	OMIM:605850
Ornithine Transcarbamylase Deficiency	Aminoaciduria	ORPHA:664
Glutamate-Cysteine Ligase Deficiency	Aminoaciduria	ORPHA:33574
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young	Hyperphosphaturia, Nephrocalcinosis, Glycosuria, Aminoaciduria, Proteinuria	OMIM:616026
Fanconi Renotubular Syndrome 5	Tubulointerstitial fibrosis, Stage 5 chronic kidney disease, Glycosuria, Aminoaciduria, Proteinuria	OMIM:618913
Saccharopinuria	Hyperlysinuria, Citrullinuria, Cystinuria	ORPHA:3124
Rowley-Rosenberg Syndrome	Aminoaciduria	OMIM:268500
Glutathione Synthetase Deficiency	Increased level of L-pyroglutamic acid in urine	OMIM:266130
Hypertryptophanemia	Tryptophanuria	OMIM:600627
Dent Disease 1	Hyperphosphaturia, Aminoaciduria, Nephrocalcinosis, Proximal tubulopathy, Nephrolithiasis, Glycos...	OMIM:300009
Galactosemia I	Increased level of galactitol in urine, Galactosuria, Albuminuria, Aminoaciduria	OMIM:230400
Succinyl-Coa:3-Oxoacid-Coa Transferase Deficiency	Elevated urinary 3-hydroxybutyric acid, Ketonuria	OMIM:245050
Combined Oxidative Phosphorylation Deficiency 52	Aminoaciduria, Renal insufficiency, Lacticaciduria	OMIM:619386
3-Hydroxyisobutyryl-Coa Hydrolase Deficiency	Aminoaciduria	OMIM:250620
Tyrosinemia, Type Iii	4-Hydroxyphenylpyruvic aciduria, Hypertyrosinemia, 4-hydroxyphenylacetic aciduria	OMIM:276710
Mitochondrial Dna Depletion Syndrome 2 (Myopathic Type)	Aminoaciduria	OMIM:609560
Familial Expansile Osteolysis	Hydroxyprolinuria	OMIM:174810
Monocarboxylate Transporter 1 Deficiency	Ketonuria	OMIM:616095
Glycine Encephalopathy	Hyperglycinuria	OMIM:605899
Dent Disease	Renal tubular atrophy, Hyperphosphaturia, Focal segmental glomerulosclerosis, Aminoaciduria, Neph...	ORPHA:1652
Hyperoxaluria, Primary, Type Iii	Hyperoxaluria, Calcium oxalate nephrolithiasis	OMIM:613616
Hawkinsinuria	4-Hydroxyphenylpyruvic aciduria, Hypertyrosinemia, 4-hydroxyphenylacetic aciduria	OMIM:140350
Combined Oxidative Phosphorylation Deficiency 14	Aminoaciduria	OMIM:614946
Hsd10 Disease	Elevated urinary 3-hydroxybutyric acid, Abnormal urinary acylglycine profile	ORPHA:391417
Hypotonia-Cystinuria Syndrome	Nephrolithiasis, Cystinuria	ORPHA:163690
Argininosuccinic Aciduria	Aminoaciduria, Oroticaciduria	ORPHA:23
Mitochondrial Dna Depletion Syndrome, Encephalomyopathic Form With Methylmalonic Aciduria	Aminoaciduria, Methylmalonic aciduria	ORPHA:1933
Sarcosinemia	Hypersarcosinuria	ORPHA:3129
Tryptophanuria With Dwarfism	Tryptophanuria	OMIM:276100
Dermotrichic Syndrome	Aminoaciduria	ORPHA:99688
Hereditary Orotic Aciduria	Aminoaciduria, Abnormality of the ureter, Oroticaciduria, Orotic acid crystalluria	ORPHA:30
Leber Congenital Amaurosis 1	Hyperthreoninuria	OMIM:204000
Succinic Semialdehyde Dehydrogenase Deficiency	Elevated urinary 4-hydroxybutyric acid, Increased level of gamma-aminobutyric acid in urine	OMIM:271980
Methylmalonic Aciduria And Homocystinuria, Cblx Type	Homocystinuria, Methylmalonic aciduria	OMIM:309541
Methylmalonyl-Coa Epimerase Deficiency	Methylmalonic aciduria, Ketonuria	OMIM:251120
Paroxysmal Nocturnal Hemoglobinuria 1	Paroxysmal nocturnal hemoglobinuria	OMIM:300818
Primary Fanconi Renotubular Syndrome	Generalized aminoaciduria, Renal sodium wasting, Bicarbonate-wasting renal tubular acidosis, Incr...	ORPHA:3337
2P21 Microdeletion Syndrome	Nephrolithiasis, Cystinuria	ORPHA:163693
Biliary Malformation With Renal Tubular Insufficiency	Generalized aminoaciduria, Renal tubular dysfunction, Glycosuria, Aminoaciduria, Proteinuria	OMIM:210550
Congenital Disorder Of Glycosylation, Type Iif	Aminoaciduria, Proteinuria	OMIM:603585
Wilson Disease	Hyperphosphaturia, Renal tubular dysfunction, Aminoaciduria, Nephrolithiasis, Glycosuria, Hyperca...	OMIM:277900
Mitochondrial Complex Iv Deficiency, Nuclear Type 1	Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Glycosuria, Aminoaciduria, ...	OMIM:220110
Cystinosis	Renal tubular dysfunction, Nephropathy, Aminoaciduria, Proteinuria, Renal insufficiency	ORPHA:213
Nephrolithiasis, Calcium Oxalate	Hyperoxaluria, Acute kidney injury, Ureteropelvic junction obstruction, Calcium oxalate nephrolit...	OMIM:167030
Encephalopathy Due To Sulfite Oxidase Deficiency	Aminoaciduria	ORPHA:833
Non-Progressive Predominantly Posterior Cavitating Leukoencephalopathy With Peripheral Neuropathy	Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Glycosuria, Aminoaciduria, ...	ORPHA:436271
Primary Hyperoxaluria Type 3	Calcium oxalate nephrolithiasis, Abnormality of urine homeostasis, Nephrocalcinosis, Hematuria, H...	ORPHA:93600
Multiple Acyl-Coa Dehydrogenase Deficiency	Ethylmalonic aciduria, Renal cortical cysts, Generalized aminoaciduria, Proximal tubulopathy, Glu...	OMIM:231680
Sialidosis Type 1	Aminoaciduria, Urinary excretion of sialylated oligosaccharides, Increased urinary O-linked sialo...	ORPHA:812
Tyrosinemia, Type Ii	4-Hydroxyphenylpyruvic aciduria, Hypertyrosinemia	OMIM:276600
Juvenile Nephropathic Cystinosis	Renal Fanconi syndrome, Proximal tubulopathy, Elevated circulating creatinine concentration, Stag...	ORPHA:411634
Primary Hyperoxaluria Type 2	Ureteral obstruction, Nephrocalcinosis, Hyperoxaluria, Nephrolithiasis, Recurrent urinary tract i...	ORPHA:93599
Fanconi-Bickel Syndrome	Hyperphosphaturia, Generalized aminoaciduria, Renal tubular dysfunction, Glycosuria	OMIM:227810
Thiamine-Responsive Megaloblastic Anemia Syndrome	Aminoaciduria	OMIM:249270
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type	Homocystinuria	OMIM:250940
Homocystinuria-Megaloblastic Anemia, Cble Complementation Type	Homocystinuria	OMIM:236270
Distal Renal Tubular Acidosis	Hyperphosphaturia, Aminoaciduria, Nephrocalcinosis, Proximal tubulopathy, Decreased glomerular fi...	ORPHA:18
Gyrate Atrophy Of Choroid And Retina	Aminoaciduria	ORPHA:414
D-Glyceric Aciduria	Aminoaciduria	OMIM:220120
Proximal Renal Tubular Acidosis	Hyperphosphaturia, Aminoaciduria, Bicarbonate-wasting renal tubular acidosis, Nephrocalcinosis, N...	ORPHA:47159
Hyperprolinemia Type 2	Prolinuria, Hydroxyprolinuria, Renal insufficiency, Increased urine alpha-ketoglutarate concentra...	ORPHA:79101
Fanconi-Bickel Syndrome	Hyperphosphaturia, Generalized aminoaciduria, Nephrocalcinosis, Renal tubular acidosis, Glycosuri...	ORPHA:2088
Tetramelic Deficiencies, Ectodermal Dysplasia, Deformed Ears, And Other Abnormalities	Aminoaciduria	OMIM:273400
Molybdenum Cofactor Deficiency, Complementation Group A	Xanthinuria, Absent urinary urothione, Increased urinary thiosulfate, Decreased urinary urate, In...	OMIM:252150
Mitochondrial Dna Depletion Syndrome 5 (Encephalomyopathic With Or Without Methylmalonic Aciduria)	Aminoaciduria, Methylmalonic aciduria	OMIM:612073
Encephalomyopathy, Mitochondrial, Due To Voltage-Dependent Anion Channel Deficiency	Aminoaciduria, Ketonuria	OMIM:614520
Canavan Disease	Elevated urinary N-acetylaspartic acid level	OMIM:271900
Neurodevelopmental Disorder With Microcephaly, Cataracts, And Renal Abnormalities	Renal hypoplasia, Aminoaciduria, Hydronephrosis	OMIM:617913
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of	Medium chain dicarboxylic aciduria, Hyperglycinuria	OMIM:201450
Hyperparathyroidism, Neonatal Severe	Hyperphosphaturia, Hypercalciuria, Polyuria, Aminoaciduria	OMIM:239200
D-Lactic Aciduria With Gout	Lacticaciduria	OMIM:245450
Infantile Nephropathic Cystinosis	Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Abnormal tubulointerstitial...	ORPHA:411629
Isovaleric Acidemia	Hyperglycinuria	OMIM:243500
Methylmalonic Aciduria And Homocystinuria, Cblc Type	Cystathioninuria, Methylmalonic aciduria, Hematuria, Homocystinuria, Hemolytic-uremic syndrome, N...	OMIM:277400
Netherton Syndrome	Ectopic kidney, Aminoaciduria, Hydronephrosis	ORPHA:634
Glutaric Acidemia Type 3	Glutaric aciduria, Ketonuria	ORPHA:35706
Methylmalonic Aciduria And Homocystinuria, Cblj Type	Homocystinuria, Methylmalonic aciduria	OMIM:614857
Bruck Syndrome 2	Hydroxyprolinuria	OMIM:609220
Autism, Susceptibility To, 3	Ketonuria	OMIM:608049
Hypotonia-Cystinuria Syndrome	Cystinuria, Nephrolithiasis	OMIM:606407
Methylmalonic Aciduria And Homocystinuria, Cblf Type	Homocystinuria, Cystathioninuria, Methylmalonic aciduria	OMIM:277380
Hartnup Disease	Neutral hyperaminoaciduria, Abnormal urinary color	ORPHA:2116
Diabetes Mellitus, Permanent Neonatal, 3	Glycosuria, Ketonuria	OMIM:618857
Peroxisome Biogenesis Disorder 2A (Zellweger)	Polycystic kidney dysplasia, Aminoaciduria	OMIM:214110
Leigh Syndrome	Ethylmalonic aciduria, Generalized aminoaciduria, Renal tubular dysfunction, Methylmalonic acidur...	ORPHA:506
3-Methylcrotonyl-Coa Carboxylase 2 Deficiency	Hyperglycinuria, Organic aciduria, Ketonuria	OMIM:210210
D-Glyceric Aciduria	Hyperglycinuria	ORPHA:941
Peroxisome Biogenesis Disorder 1A (Zellweger)	Hypospadias, Hydronephrosis, Albuminuria, Renal cortical microcysts, Aminoaciduria	OMIM:214100
Citrullinemia, Type Ii, Adult-Onset	Argininosuccinic aciduria	OMIM:603471
Methylmalonic Aciduria And Homocystinuria, Cbld Type	Homocystinuria, Methylmalonic aciduria	OMIM:277410
Paget Disease Of Bone 2, Early-Onset	Hydroxyprolinuria	OMIM:602080
Fumarase Deficiency	Aminoaciduria	OMIM:606812
Molybdenum Cofactor Deficiency, Complementation Group B	Xanthinuria, Increased urinary hypoxanthine, Xanthine nephrolithiasis, Increased urinary taurine	OMIM:252160
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)	Generalized aminoaciduria	OMIM:251880
Fructose Intolerance, Hereditary	Hyperphosphaturia, Transient aminoaciduria, Proximal tubulopathy, Proximal renal tubular acidosis...	OMIM:229600
Mitochondrial Complex Iii Deficiency, Nuclear Type 1	Aminoaciduria, Tubulointerstitial nephritis	OMIM:124000
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency	Glycosuria, Ketonuria	ORPHA:2089
Vitamin D Hydroxylation-Deficient Rickets, Type 1A	Generalized aminoaciduria	OMIM:264700
Homocystinuria Due To Cystathionine Beta-Synthase Deficiency	Methioninuria, Homocystinuria	OMIM:236200
Propionic Acidemia	Increased level of hippuric acid in urine, Hyperglycinuria	OMIM:606054
Sideroblastic Anemia With B-Cell Immunodeficiency, Periodic Fevers, And Developmental Delay	Aminoaciduria, Nephrocalcinosis	OMIM:616084
Argininosuccinic Aciduria	Aminoaciduria, Oroticaciduria	OMIM:207900
Paget Disease Of Bone 5, Juvenile-Onset	Hydroxyprolinuria	OMIM:239000
Molybdenum Cofactor Deficiency, Complementation Group C	Increased urinary taurine	OMIM:615501
Cystinosis, Nephropathic	Renal Fanconi syndrome, Generalized aminoaciduria, Nephrolithiasis, Glycosuria, Stage 5 chronic k...	OMIM:219800
Argininemia	Oroticaciduria, Diaminoaciduria	OMIM:207800
Mitochondrial Complex Iv Deficiency, Nuclear Type 12	Aminoaciduria	OMIM:619055
Mitochondrial Complex Iv Deficiency, Nuclear Type 22	Ethylmalonic aciduria, Dicarboxylic aciduria, Increased urine alpha-ketoglutarate concentration, ...	OMIM:619355
Kanzaki Disease	Aminoaciduria, Increased urinary O-linked sialopeptides	OMIM:609242
Hyperlysinemia	Hyperlysinuria, Decreased urine alpha-ketoglutarate concentration, Argininuria, Cystinuria	ORPHA:2203
Tubulointerstitial Nephritis And Uveitis Syndrome	Renal lymphocytic tubulitis, Renal Fanconi syndrome, Tubulointerstitial nephritis, Aminoaciduria,...	ORPHA:91500
Hypocalcemic Vitamin D-Dependent Rickets	Generalized aminoaciduria	ORPHA:289157
Oculocerebrorenal Syndrome Of Lowe	Nephrocalcinosis, Hematuria, Nephrolithiasis, Proximal renal tubular acidosis, Oligosacchariduria...	ORPHA:534
Lowe Oculocerebrorenal Syndrome	Hyperphosphaturia, Renal Fanconi syndrome, Proximal renal tubular acidosis, Aminoaciduria, Protei...	OMIM:309000
Alkaptonuria	Aminoaciduria, Nephrolithiasis	ORPHA:56
Lysinuric Protein Intolerance	Aminoaciduria, Oroticaciduria, Stage 5 chronic kidney disease	OMIM:222700
Lysinuric Protein Intolerance	Oroticaciduria, Tubulointerstitial nephritis, Ornithinuria, Decreased glomerular filtration rate,...	ORPHA:470
Interstitial Lung And Liver Disease	Aminoaciduria	OMIM:615486
X-Linked Intellectual Disability, Armfield Type	Galactosuria, Aminoaciduria, Organic aciduria	ORPHA:85276
Xeroderma Pigmentosum	Aminoaciduria	ORPHA:910
Homocystinuria Due To Methylene Tetrahydrofolate Reductase Deficiency	Homocystinuria	ORPHA:395
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome	Generalized aminoaciduria	ORPHA:404454
Aspartylglucosaminuria	Aspartylglucosaminuria	ORPHA:93
Aspartylglucosaminuria	Aspartylglucosaminuria	OMIM:208400

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hal

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hal.

No publications found that use IMPC mice or data for Hal.

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MGI Allele	Allele Type	Produced
Hal^{tm50511(L1L2_Bact_P)}	KO first allele (reporter-tagged insertion with conditional potential)	Targeting vectors

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