Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
histidine ammonia lyase
Synonyms:
Hsd,  histidase

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Hal mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Hal by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Histidinemia
Hyperhistidinemia, Histidinuria OMIM:235800
Histidinemia
Hyperhistidinemia, Histidinuria ORPHA:2157

The table below shows human diseases predicted to be associated to Hal by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Indolylacroyl Glycinuria With Mental Retardation
Hyperglycinuria OMIM:243050
Iminoglycinuria
Prolinuria, Hydroxyprolinuria, Hyperglycinuria OMIM:242600
Iminoglycinuria
Prolinuria, Hydroxyprolinuria, Hyperglycinuria ORPHA:42062
Beta-Aminoisobutyric Aciduria
Beta-aminoisobutyric aciduria OMIM:210100
Cystathioninuria
Cystathioninuria OMIM:219500
Phenylketonuria
Aminoaciduria ORPHA:716
Dibasic Amino Aciduria I
Argininuria, Dibasicaminoaciduria, Hyperlysinuria, Ornithinuria OMIM:222690
Uridine-Cytidineuria
Elevated urinary cytidine, Elevated uridine in urine OMIM:618477
Methylmalonic Aciduria, Transient, Due To Transcobalamin Receptor Defect
Methylmalonic aciduria OMIM:613646
Sedoheptulokinase Deficiency
Increased urinary sedoheptulose OMIM:617213
Lysine Malabsorption Syndrome
Hyperlysinuria, Renal tubular lysine transport defect OMIM:247950
Seizures-Intellectual Disability Due To Hydroxylysinuria Syndrome
Aminoaciduria ORPHA:79156
Hyperprolinemia, Type Ii
Prolinuria, Hydroxyprolinuria, Hyperglycinuria OMIM:239510
Carnosinemia
Carnosinuria OMIM:212200
Hydroxylysinuria
Hyperlysinuria OMIM:236900
Cystinuria
Ornithinuria, Nephrolithiasis, Cystinuria, Recurrent urinary tract infections, Argininuria, Hyper... OMIM:220100
Hyperglycinuria
Hyperglycinuria, Calcium oxalate nephrolithiasis OMIM:138500
Glucoglycinuria
Hyperglycinuria, Glycosuria OMIM:138070
Camptodactyly-Taurinuria Syndrome
Aminoaciduria, Increased urinary taurine ORPHA:1325
Pentosuria
Abnormality of urine homeostasis OMIM:260800
Dicarboxylic Aminoaciduria
Aminoaciduria, Nephrolithiasis, Aspartic aciduria OMIM:222730
Tiglic Acidemia
Aminoaciduria OMIM:275190
Saccharopinuria
Citrullinuria, Saccharopinuria, Hyperlysinuria, Histidinuria OMIM:268700
Hyperprolinemia Type 1
Prolinuria, Proteinuria, Nephropathy ORPHA:419
Ichthyosis, Split Hairs, And Amino Aciduria
Aminoaciduria OMIM:242550
Carnosinase Deficiency
Carnosinuria ORPHA:1361
Threoninemia
Hyperthreoninuria OMIM:273770
Camptodactyly 1
Increased urinary taurine OMIM:114200
Diaminopentanuria
Hyperlysinuria, Cystinuria OMIM:222350
Alpha-Aminoadipic And Alpha-Ketoadipic Aciduria
Alpha-aminoadipic aciduria OMIM:204750
Proteinuria, Low Molecular Weight, With Hypercalciuria And Nephrocalcinosis
Renal tubular atrophy, Focal segmental glomerulosclerosis, Nephrocalcinosis, Proximal tubulopathy... OMIM:308990
Cerebral Creatine Deficiency Syndrome 3
Organic aciduria OMIM:612718
Homocarnosinosis
Carnosinuria OMIM:236130
Hyperoxaluria, Primary, Type Ii
Calcium oxalate nephrolithiasis, Nephrocalcinosis, Hyperoxaluria, Hematuria, Aminoaciduria, Renal... OMIM:260000
Histidinemia
Hyperhistidinemia, Histidinuria OMIM:235800
5-Oxoprolinase Deficiency
Prolinuria, Increased level of L-pyroglutamic acid in urine, Calcium oxalate nephrolithiasis OMIM:260005
Hyper-Beta-Alaninemia
Increased urinary taurine OMIM:237400
Amino Aciduria With Mental Deficiency, Dwarfism, Muscular Dystrophy, Osteoporosis, And Acidosis
Aminoaciduria OMIM:204730
Hyperprolinemia, Type I
Prolinuria, Hydroxyprolinuria, Hyperglycinuria OMIM:239500
Glutamate Formiminotransferase Deficiency
Aminoaciduria OMIM:229100
Nephrotic Syndrome, Type 16
Hematuria, Proteinuria, Nephrotic syndrome OMIM:617783
Mercaptolactate-Cysteine Disulfiduria
Aminoaciduria OMIM:249650
Ichthyosis-Intellectual Disability-Dwarfism-Renal Impairment Syndrome
Aminoaciduria ORPHA:2278
Macular Dystrophy, Retinal, 1, North Carolina Type
Generalized aminoaciduria OMIM:136550
Fanconi Renotubular Syndrome 3
Hyperphosphaturia, Aminoaciduria, Proteinuria, Glycosuria OMIM:615605
Valinemia
Valinuria OMIM:277100
Muscular Dystrophy, Cardiac Type
Carnosinuria OMIM:309930
Hyperlysinuria With Hyperammonemia
Hyperlysinuria, Dibasicaminoaciduria OMIM:238750
Cystathioninuria
Cystathioninuria, Nephrolithiasis ORPHA:212
Histidinemia
Hyperhistidinemia, Histidinuria ORPHA:2157
Galactosemia Iii
Aminoaciduria, Galactosuria OMIM:230350
Hydroxykynureninuria
Aminoaciduria, Renal tubular dysfunction OMIM:236800
Hartnup Disorder
Neutral hyperaminoaciduria OMIM:234500
Stimmler Syndrome
Aminoaciduria ORPHA:3199
Tyrosinemia Type 1
Generalized aminoaciduria ORPHA:882
Gracile Syndrome
Aminoaciduria OMIM:603358
Proteinuria, Chronic Benign
Albuminuria, Proteinuria OMIM:618884
Homocystinuria Due To Deficiency Of N(5,10)-Methylenetetrahydrofolate Reductase Activity
Homocystinuria OMIM:236250
Homozygous 11P15-P14 Deletion Syndrome
Generalized aminoaciduria, Renal tubular dysfunction OMIM:606528
Dent Disease 2
Nephrocalcinosis, Proximal tubulopathy, Low-molecular-weight proteinuria, Chronic kidney disease,... OMIM:300555
3-Hydroxyisobutyric Aciduria
Aminoaciduria OMIM:236795
Fanconi Renotubular Syndrome 2
Generalized aminoaciduria, Proximal tubulopathy, Glycosuria, Hypercalciuria, Renal insufficiency OMIM:613388
Fanconi Renotubular Syndrome 1
Renal tubular dysfunction, Lacticaciduria, Glycosuria, Aminoaciduria, Proteinuria, Renal insuffic... OMIM:134600
Carbamoyl-Phosphate Synthetase 1 Deficiency
Aminoaciduria ORPHA:147
Argininemia
Diaminoaciduria ORPHA:90
Alaninuria With Microcephaly, Dwarfism, Enamel Hypoplasia, And Diabetes Mellitus
Alaninuria OMIM:202900
Combined Oxidative Phosphorylation Deficiency 36
Aciduria OMIM:617950
Neonatal Severe Primary Hyperparathyroidism
Aminoaciduria ORPHA:417
Histidinuria Due To A Renal Tubular Defect
Histidinuria, Impaired histidine renal tubular absorption OMIM:235830
Methionine Malabsorption Syndrome
Aminoaciduria OMIM:250900
Histidinuria-Renal Tubular Defect Syndrome
Histidinuria, Impaired histidine renal tubular absorption ORPHA:2158
Mitochondrial Dna Depletion Syndrome 8A (Encephalomyopathic Type With Renal Tubulopathy)
Proximal tubulopathy, Aminoaciduria OMIM:612075
Galactose Epimerase Deficiency
Aminoaciduria ORPHA:79238
Dimethylglycine Dehydrogenase Deficiency
Elevated urinary N,N-dimethylglycine level OMIM:605850
Ornithine Transcarbamylase Deficiency
Aminoaciduria ORPHA:664
Glutamate-Cysteine Ligase Deficiency
Aminoaciduria ORPHA:33574
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young
Hyperphosphaturia, Nephrocalcinosis, Glycosuria, Aminoaciduria, Proteinuria OMIM:616026
Fanconi Renotubular Syndrome 5
Tubulointerstitial fibrosis, Stage 5 chronic kidney disease, Glycosuria, Aminoaciduria, Proteinuria OMIM:618913
Saccharopinuria
Hyperlysinuria, Citrullinuria, Cystinuria ORPHA:3124
Rowley-Rosenberg Syndrome
Aminoaciduria OMIM:268500
Glutathione Synthetase Deficiency
Increased level of L-pyroglutamic acid in urine OMIM:266130
Hypertryptophanemia
Tryptophanuria OMIM:600627
Dent Disease 1
Hyperphosphaturia, Aminoaciduria, Nephrocalcinosis, Proximal tubulopathy, Nephrolithiasis, Glycos... OMIM:300009
Galactosemia I
Increased level of galactitol in urine, Galactosuria, Albuminuria, Aminoaciduria OMIM:230400
Succinyl-Coa:3-Oxoacid-Coa Transferase Deficiency
Elevated urinary 3-hydroxybutyric acid, Ketonuria OMIM:245050
Combined Oxidative Phosphorylation Deficiency 52
Aminoaciduria, Renal insufficiency, Lacticaciduria OMIM:619386
3-Hydroxyisobutyryl-Coa Hydrolase Deficiency
Aminoaciduria OMIM:250620
Tyrosinemia, Type Iii
4-Hydroxyphenylpyruvic aciduria, Hypertyrosinemia, 4-hydroxyphenylacetic aciduria OMIM:276710
Mitochondrial Dna Depletion Syndrome 2 (Myopathic Type)
Aminoaciduria OMIM:609560
Familial Expansile Osteolysis
Hydroxyprolinuria OMIM:174810
Monocarboxylate Transporter 1 Deficiency
Ketonuria OMIM:616095
Glycine Encephalopathy
Hyperglycinuria OMIM:605899
Dent Disease
Renal tubular atrophy, Hyperphosphaturia, Focal segmental glomerulosclerosis, Aminoaciduria, Neph... ORPHA:1652
Hyperoxaluria, Primary, Type Iii
Hyperoxaluria, Calcium oxalate nephrolithiasis OMIM:613616
Hawkinsinuria
4-Hydroxyphenylpyruvic aciduria, Hypertyrosinemia, 4-hydroxyphenylacetic aciduria OMIM:140350
Combined Oxidative Phosphorylation Deficiency 14
Aminoaciduria OMIM:614946
Hsd10 Disease
Elevated urinary 3-hydroxybutyric acid, Abnormal urinary acylglycine profile ORPHA:391417
Hypotonia-Cystinuria Syndrome
Nephrolithiasis, Cystinuria ORPHA:163690
Argininosuccinic Aciduria
Aminoaciduria, Oroticaciduria ORPHA:23
Mitochondrial Dna Depletion Syndrome, Encephalomyopathic Form With Methylmalonic Aciduria
Aminoaciduria, Methylmalonic aciduria ORPHA:1933
Sarcosinemia
Hypersarcosinuria ORPHA:3129
Tryptophanuria With Dwarfism
Tryptophanuria OMIM:276100
Dermotrichic Syndrome
Aminoaciduria ORPHA:99688
Hereditary Orotic Aciduria
Aminoaciduria, Abnormality of the ureter, Oroticaciduria, Orotic acid crystalluria ORPHA:30
Leber Congenital Amaurosis 1
Hyperthreoninuria OMIM:204000
Succinic Semialdehyde Dehydrogenase Deficiency
Elevated urinary 4-hydroxybutyric acid, Increased level of gamma-aminobutyric acid in urine OMIM:271980
Methylmalonic Aciduria And Homocystinuria, Cblx Type
Homocystinuria, Methylmalonic aciduria OMIM:309541
Methylmalonyl-Coa Epimerase Deficiency
Methylmalonic aciduria, Ketonuria OMIM:251120
Paroxysmal Nocturnal Hemoglobinuria 1
Paroxysmal nocturnal hemoglobinuria OMIM:300818
Primary Fanconi Renotubular Syndrome
Generalized aminoaciduria, Renal sodium wasting, Bicarbonate-wasting renal tubular acidosis, Incr... ORPHA:3337
2P21 Microdeletion Syndrome
Nephrolithiasis, Cystinuria ORPHA:163693
Biliary Malformation With Renal Tubular Insufficiency
Generalized aminoaciduria, Renal tubular dysfunction, Glycosuria, Aminoaciduria, Proteinuria OMIM:210550
Congenital Disorder Of Glycosylation, Type Iif
Aminoaciduria, Proteinuria OMIM:603585
Wilson Disease
Hyperphosphaturia, Renal tubular dysfunction, Aminoaciduria, Nephrolithiasis, Glycosuria, Hyperca... OMIM:277900
Mitochondrial Complex Iv Deficiency, Nuclear Type 1
Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Glycosuria, Aminoaciduria, ... OMIM:220110
Cystinosis
Renal tubular dysfunction, Nephropathy, Aminoaciduria, Proteinuria, Renal insufficiency ORPHA:213
Nephrolithiasis, Calcium Oxalate
Hyperoxaluria, Acute kidney injury, Ureteropelvic junction obstruction, Calcium oxalate nephrolit... OMIM:167030
Encephalopathy Due To Sulfite Oxidase Deficiency
Aminoaciduria ORPHA:833
Non-Progressive Predominantly Posterior Cavitating Leukoencephalopathy With Peripheral Neuropathy
Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Glycosuria, Aminoaciduria, ... ORPHA:436271
Primary Hyperoxaluria Type 3
Calcium oxalate nephrolithiasis, Abnormality of urine homeostasis, Nephrocalcinosis, Hematuria, H... ORPHA:93600
Multiple Acyl-Coa Dehydrogenase Deficiency
Ethylmalonic aciduria, Renal cortical cysts, Generalized aminoaciduria, Proximal tubulopathy, Glu... OMIM:231680
Sialidosis Type 1
Aminoaciduria, Urinary excretion of sialylated oligosaccharides, Increased urinary O-linked sialo... ORPHA:812
Tyrosinemia, Type Ii
4-Hydroxyphenylpyruvic aciduria, Hypertyrosinemia OMIM:276600
Juvenile Nephropathic Cystinosis
Renal Fanconi syndrome, Proximal tubulopathy, Elevated circulating creatinine concentration, Stag... ORPHA:411634
Primary Hyperoxaluria Type 2
Ureteral obstruction, Nephrocalcinosis, Hyperoxaluria, Nephrolithiasis, Recurrent urinary tract i... ORPHA:93599
Fanconi-Bickel Syndrome
Hyperphosphaturia, Generalized aminoaciduria, Renal tubular dysfunction, Glycosuria OMIM:227810
Thiamine-Responsive Megaloblastic Anemia Syndrome
Aminoaciduria OMIM:249270
Homocystinuria-Megaloblastic Anemia, Cblg Complementation Type
Homocystinuria OMIM:250940
Homocystinuria-Megaloblastic Anemia, Cble Complementation Type
Homocystinuria OMIM:236270
Distal Renal Tubular Acidosis
Hyperphosphaturia, Aminoaciduria, Nephrocalcinosis, Proximal tubulopathy, Decreased glomerular fi... ORPHA:18
Gyrate Atrophy Of Choroid And Retina
Aminoaciduria ORPHA:414
D-Glyceric Aciduria
Aminoaciduria OMIM:220120
Proximal Renal Tubular Acidosis
Hyperphosphaturia, Aminoaciduria, Bicarbonate-wasting renal tubular acidosis, Nephrocalcinosis, N... ORPHA:47159
Hyperprolinemia Type 2
Prolinuria, Hydroxyprolinuria, Renal insufficiency, Increased urine alpha-ketoglutarate concentra... ORPHA:79101
Fanconi-Bickel Syndrome
Hyperphosphaturia, Generalized aminoaciduria, Nephrocalcinosis, Renal tubular acidosis, Glycosuri... ORPHA:2088
Tetramelic Deficiencies, Ectodermal Dysplasia, Deformed Ears, And Other Abnormalities
Aminoaciduria OMIM:273400
Molybdenum Cofactor Deficiency, Complementation Group A
Xanthinuria, Absent urinary urothione, Increased urinary thiosulfate, Decreased urinary urate, In... OMIM:252150
Mitochondrial Dna Depletion Syndrome 5 (Encephalomyopathic With Or Without Methylmalonic Aciduria)
Aminoaciduria, Methylmalonic aciduria OMIM:612073
Encephalomyopathy, Mitochondrial, Due To Voltage-Dependent Anion Channel Deficiency
Aminoaciduria, Ketonuria OMIM:614520
Canavan Disease
Elevated urinary N-acetylaspartic acid level OMIM:271900
Neurodevelopmental Disorder With Microcephaly, Cataracts, And Renal Abnormalities
Renal hypoplasia, Aminoaciduria, Hydronephrosis OMIM:617913
Acyl-Coa Dehydrogenase, Medium-Chain, Deficiency Of
Medium chain dicarboxylic aciduria, Hyperglycinuria OMIM:201450
Hyperparathyroidism, Neonatal Severe
Hyperphosphaturia, Hypercalciuria, Polyuria, Aminoaciduria OMIM:239200
D-Lactic Aciduria With Gout
Lacticaciduria OMIM:245450
Infantile Nephropathic Cystinosis
Hyperphosphaturia, Renal Fanconi syndrome, Renal tubular dysfunction, Abnormal tubulointerstitial... ORPHA:411629
Isovaleric Acidemia
Hyperglycinuria OMIM:243500
Methylmalonic Aciduria And Homocystinuria, Cblc Type
Cystathioninuria, Methylmalonic aciduria, Hematuria, Homocystinuria, Hemolytic-uremic syndrome, N... OMIM:277400
Netherton Syndrome
Ectopic kidney, Aminoaciduria, Hydronephrosis ORPHA:634
Glutaric Acidemia Type 3
Glutaric aciduria, Ketonuria ORPHA:35706
Methylmalonic Aciduria And Homocystinuria, Cblj Type
Homocystinuria, Methylmalonic aciduria OMIM:614857
Bruck Syndrome 2
Hydroxyprolinuria OMIM:609220
Autism, Susceptibility To, 3
Ketonuria OMIM:608049
Hypotonia-Cystinuria Syndrome
Cystinuria, Nephrolithiasis OMIM:606407
Methylmalonic Aciduria And Homocystinuria, Cblf Type
Homocystinuria, Cystathioninuria, Methylmalonic aciduria OMIM:277380
Hartnup Disease
Neutral hyperaminoaciduria, Abnormal urinary color ORPHA:2116
Diabetes Mellitus, Permanent Neonatal, 3
Glycosuria, Ketonuria OMIM:618857
Peroxisome Biogenesis Disorder 2A (Zellweger)
Polycystic kidney dysplasia, Aminoaciduria OMIM:214110
Leigh Syndrome
Ethylmalonic aciduria, Generalized aminoaciduria, Renal tubular dysfunction, Methylmalonic acidur... ORPHA:506
3-Methylcrotonyl-Coa Carboxylase 2 Deficiency
Hyperglycinuria, Organic aciduria, Ketonuria OMIM:210210
D-Glyceric Aciduria
Hyperglycinuria ORPHA:941
Peroxisome Biogenesis Disorder 1A (Zellweger)
Hypospadias, Hydronephrosis, Albuminuria, Renal cortical microcysts, Aminoaciduria OMIM:214100
Citrullinemia, Type Ii, Adult-Onset
Argininosuccinic aciduria OMIM:603471
Methylmalonic Aciduria And Homocystinuria, Cbld Type
Homocystinuria, Methylmalonic aciduria OMIM:277410
Paget Disease Of Bone 2, Early-Onset
Hydroxyprolinuria OMIM:602080
Fumarase Deficiency
Aminoaciduria OMIM:606812
Molybdenum Cofactor Deficiency, Complementation Group B
Xanthinuria, Increased urinary hypoxanthine, Xanthine nephrolithiasis, Increased urinary taurine OMIM:252160
Mitochondrial Dna Depletion Syndrome 3 (Hepatocerebral Type)
Generalized aminoaciduria OMIM:251880
Fructose Intolerance, Hereditary
Hyperphosphaturia, Transient aminoaciduria, Proximal tubulopathy, Proximal renal tubular acidosis... OMIM:229600
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Aminoaciduria, Tubulointerstitial nephritis OMIM:124000
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Glycosuria, Ketonuria ORPHA:2089
Vitamin D Hydroxylation-Deficient Rickets, Type 1A
Generalized aminoaciduria OMIM:264700
Homocystinuria Due To Cystathionine Beta-Synthase Deficiency
Methioninuria, Homocystinuria OMIM:236200
Propionic Acidemia
Increased level of hippuric acid in urine, Hyperglycinuria OMIM:606054
Sideroblastic Anemia With B-Cell Immunodeficiency, Periodic Fevers, And Developmental Delay
Aminoaciduria, Nephrocalcinosis OMIM:616084
Argininosuccinic Aciduria
Aminoaciduria, Oroticaciduria OMIM:207900
Paget Disease Of Bone 5, Juvenile-Onset
Hydroxyprolinuria OMIM:239000
Molybdenum Cofactor Deficiency, Complementation Group C
Increased urinary taurine OMIM:615501
Cystinosis, Nephropathic
Renal Fanconi syndrome, Generalized aminoaciduria, Nephrolithiasis, Glycosuria, Stage 5 chronic k... OMIM:219800
Argininemia
Oroticaciduria, Diaminoaciduria OMIM:207800
Mitochondrial Complex Iv Deficiency, Nuclear Type 12
Aminoaciduria OMIM:619055
Mitochondrial Complex Iv Deficiency, Nuclear Type 22
Ethylmalonic aciduria, Dicarboxylic aciduria, Increased urine alpha-ketoglutarate concentration, ... OMIM:619355
Kanzaki Disease
Aminoaciduria, Increased urinary O-linked sialopeptides OMIM:609242
Hyperlysinemia
Hyperlysinuria, Decreased urine alpha-ketoglutarate concentration, Argininuria, Cystinuria ORPHA:2203
Tubulointerstitial Nephritis And Uveitis Syndrome
Renal lymphocytic tubulitis, Renal Fanconi syndrome, Tubulointerstitial nephritis, Aminoaciduria,... ORPHA:91500
Hypocalcemic Vitamin D-Dependent Rickets
Generalized aminoaciduria ORPHA:289157
Oculocerebrorenal Syndrome Of Lowe
Nephrocalcinosis, Hematuria, Nephrolithiasis, Proximal renal tubular acidosis, Oligosacchariduria... ORPHA:534
Lowe Oculocerebrorenal Syndrome
Hyperphosphaturia, Renal Fanconi syndrome, Proximal renal tubular acidosis, Aminoaciduria, Protei... OMIM:309000
Alkaptonuria
Aminoaciduria, Nephrolithiasis ORPHA:56
Lysinuric Protein Intolerance
Aminoaciduria, Oroticaciduria, Stage 5 chronic kidney disease OMIM:222700
Lysinuric Protein Intolerance
Oroticaciduria, Tubulointerstitial nephritis, Ornithinuria, Decreased glomerular filtration rate,... ORPHA:470
Interstitial Lung And Liver Disease
Aminoaciduria OMIM:615486
X-Linked Intellectual Disability, Armfield Type
Galactosuria, Aminoaciduria, Organic aciduria ORPHA:85276
Xeroderma Pigmentosum
Aminoaciduria ORPHA:910
Homocystinuria Due To Methylene Tetrahydrofolate Reductase Deficiency
Homocystinuria ORPHA:395
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Generalized aminoaciduria ORPHA:404454
Aspartylglucosaminuria
Aspartylglucosaminuria ORPHA:93
Aspartylglucosaminuria
Aspartylglucosaminuria OMIM:208400

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Hal

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Hal.

No publications found that use IMPC mice or data for Hal.

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MGI Allele Allele Type Produced
Haltm50511(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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