Clps | colipase, pancreatic

Physiological systems

19 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Mortality/aging

18 No significant impact

5 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsClpstm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

adrenal glandheterozygoten/a0% (0/1)0.7% (4/570)
aortaheterozygoten/a0% (0/1)0.19% (1/533)
bloodheterozygoten/a0% (0/1)0% (0/17)
bone marrowheterozygoten/a0% (0/1)0% (0/22)
brainheterozygoten/a0% (0/1)0.86% (5/579)
brainstemheterozygoten/an/a0.41% (2/490)
brown adipose tissueheterozygoten/a0% (0/1)0% (0/588)
cartilage tissueheterozygoten/an/a0.22% (1/454)
cecumheterozygoten/a0% (0/1)7.75% (22/284)
cerebellumheterozygoten/a0% (0/1)0.56% (3/532)
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Histopathology

IMPC related publications

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Clpstm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Clpstm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
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Clpstm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
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