Dsg1b - desmoglein 1 beta | International Mouse Phenotyping Consortium

Genes Phenotypes

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Gene: Dsg1b

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Name

desmoglein 1 beta

MGI ID

MGI:2664357

Synonyms

Dsg5

Viability

Homozygous - Viable

Embryo viewer

N/A

Other links

MGI Ensembl

Significant phenotypes (10) Measurements chart (284) All data table (345)

Expression & images (0) Disease models (0) Order (1)

Significant

Not Significant

Not tested

View body weight measurements

Phenotype	System	Allele	Zyg	Sex	Life Stage	P Value
cataract		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	1.09×10^-05
abnormal iris morphology		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	3.15×10^-05
abnormal lens morphology		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	1.09×10^-05
abnormal eyelid morphology		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	3.48×10^-13
matted coat		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	2.69×10^-06
increased lean body mass		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	4.04×10^-05
abnormal bone structure		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	7.65×10^-05
abnormal cornea morphology		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	6.87×10^-08
decreased total body fat amount		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	3.12×10^-05
increased bone mineral content		Dsg1b^{tm1a(KOMP)Wtsi}	HOM		Early adult	1.01×10^-06

Download data as: TSV XLS

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Viewing: all phenotypes

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Viewing: all phenotypes

Expression

Expression data not available

Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
28 Images

X-ray: XRay Images Skull Lateral Orientation
14 Images

X-ray: XRay Images Whole Body Dorso Ventral
42 Images

X-ray: XRay Images Forepaw
14 Images

X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images

Legacy Phenotype Associated Images

Dsg1b^{tm1a(KOMP)Wtsi}
WT, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
WT, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
WT, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
WT, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
WT, Female, WTSI

View all 85 images

Dsg1b^{tm1a(KOMP)Wtsi}
abnormal cornea morphology, HOM, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
abnormal cornea morphology, HOM, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
left eye, HOM, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
right eye, HOM, Female, WTSI

Dsg1b^{tm1a(KOMP)Wtsi}
right eye, HOM, Female, WTSI

View all 20 images

Dsg1b^{tm1a(KOMP)Wtsi}
back skin, HOM, Female, WTSI

Disease Models

By Annotation and Orthology (0)
By phenotypic Similarity (0)

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MGI Allele	Allele Type	Produced
Dsg1b^{tm1a(KOMP)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells

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