Baiap2l2 | BAI1-associated protein 2-like 2

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Muscle Hearing/vestibular/ear Nervous system Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating bilirubin level1 supporting datasetBaiap2l2tm1a(EUCOMM)HmguhomozygoteEarly adult3.86x10-5 
abnormal startle reflex1 supporting datasetBaiap2l2tm1b(EUCOMM)HmguhomozygoteEarly adult1.24x10-15 
abnormal auditory brainstem response4 supporting datasetsBaiap2l2tm1b(EUCOMM)HmguhomozygoteEarly adult1.58x10-24 
increased cardiac muscle contractility1 supporting datasetBaiap2l2tm1a(EUCOMM)HmguhomozygoteEarly adult4.75x10-7 
decreased prepulse inhibition5 supporting datasetsBaiap2l2tm1b(EUCOMM)HmguhomozygoteEarly adult1.74x10-13 
abnormal auditory brainstem response5 supporting datasetsBaiap2l2tm1a(EUCOMM)HmguhomozygoteEarly adult5.25x10-10 
decreased startle reflex1 supporting datasetBaiap2l2tm1a(EUCOMM)HmguhomozygoteEarly adult8.69x10-8 
decreased grip strength2 supporting datasetsBaiap2l2tm1a(EUCOMM)HmguhomozygoteEarly adult2.54x10-5 
abnormal gait1 supporting datasetBaiap2l2tm1b(EUCOMM)HmguhomozygoteEarly adult7.32x10-5 
decreased hematocrit1 supporting datasetBaiap2l2tm1b(EUCOMM)HmguhomozygoteEarly adult5.61x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Baiap2l2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Baiap2l2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Baiap2l2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Baiap2l2tm83489(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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