Gene: Chd2

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Name
chromodomain helicase DNA binding protein 2
MGI ID
MGI:2448567
Synonyms
2810040A01Rik 2810013C04Rik 5630401D06Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased erythrocyte cell number Chd2tm1b(EUCOMM)Hmgu HOM Early adult 6.10×10-06
increased mean corpuscular volume Chd2tm1b(EUCOMM)Hmgu HOM Early adult 4.27×10-05
increased grip strength Chd2tm1b(EUCOMM)Hmgu HOM Early adult 1.55×10-10
increased circulating aspartate transaminase level Chd2tm1b(EUCOMM)Hmgu HOM Early adult 1.47×10-08
decreased bone mineral density Chd2tm1b(EUCOMM)Hmgu HOM Early adult 5.91×10-05
decreased bone mineral content Chd2tm1b(EUCOMM)Hmgu HOM Early adult 3.58×10-06
decreased hemoglobin content Chd2tm1b(EUCOMM)Hmgu HOM Early adult 2.74×10-05
short tibia Chd2tm1b(EUCOMM)Hmgu HOM Early adult 2.93×10-11
abnormal bone structure Chd2tm1b(EUCOMM)Hmgu HOM Early adult 4.87×10-06
abnormal sinus arrhythmia Chd2tm1b(EUCOMM)Hmgu HOM Early adult 2.07×10-08
decreased body length Chd2tm1b(EUCOMM)Hmgu HOM Early adult 4.19×10-06
decreased mean platelet volume Chd2tm1b(EUCOMM)Hmgu HOM Early adult 1.11×10-05

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 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Ophthalmoscopy
2 Images
Histopathology
2 Images
Electrocardiogram (ECG): Waveform Image
1 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Sternum - MPATH pathological process term fibro-osseous lesion Chd2tm1b(EUCOMM)Hmgu HOM Early adult
Sternum - MPATH pathological process term hyperplasia Chd2tm1b(EUCOMM)Hmgu HOM Early adult

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MGI Allele Allele Type Produced
Chd2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Chd2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Chd2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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