Genes Phenotypes

Gene: Marveld2

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Name
MARVEL (membrane-associating) domain containing 2
MGI ID
MGI:2446166
Synonyms
Tric-b Tric-c Mrvldc2 Tricellulin Tric Tric-a
Viability
Homozygous - Viable
Embryo Screen
N/A
Other links
MGI   Ensembl  
Significant phenotypes (6) Measurements chart (233) All data table (351)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased prepulse inhibition Marveld2tm1b(EUCOMM)Wtsi HOM postnatal 5.62×10-06
decreased startle reflex Marveld2tm1b(EUCOMM)Wtsi HOM postnatal 6.62×10-21
increased or absent threshold for auditory brainstem response Marveld2tm1b(EUCOMM)Wtsi HOM postnatal 2.00×10-06
absent startle reflex Marveld2tm1b(EUCOMM)Wtsi HOM postnatal 2.33×10-16
abnormal ear morphology Marveld2tm1b(EUCOMM)Wtsi HOM postnatal 4.21×10-15
enlarged heart Marveld2tm1b(EUCOMM)Wtsi HOM postnatal 0.00

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (1/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (1/2)  Wholemount images
Gall bladder 2 No  (1/2)  Wholemount images
Heart 2 No N/A
Hippocampus 2 No  (1/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2)  Wholemount images
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No N/A
Olfactory lobe 2 No  (1/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (1/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No  (2/2)  Wholemount images
Thyroid gland 2 No  (15/584)  (2/2)  Wholemount images
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
digestive system (5)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
immune system (3)
Lymph Node expression
MA:0000139
integumental system (1)
Skin expression
MA:0000151
nervous system (5)
Cerebral Cortex expression
Hippocampus expression
Brain expression
MA:0000185
MA:0000191
MA:0000168
postnatal mouse (22)
Adrenal gland expression
MA:0000116
reproductive system (3)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
trunk (13)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485) N/A
Ear 2  (1/485)  (1/4) N/A
Embryo 2  (1/485)  (3/4) N/A
Eye 2  (1/485)  (1/4) N/A
Foot 2  (1/485)  (3/4) N/A
Forebrain 2  (1/485) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485)  (3/4) N/A
Head 2  (5/485)  (3/4) N/A
Heart 2  (1/485) N/A
Hindbrain 2  (6/485) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485)  (1/4) N/A
Skin 2  (1/485)  (3/4) N/A
Tail 2  (1/485)  (2/4) N/A
Tail somite 2  (1/485) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
11 Images
Echo: M-Mode Images
28 Images
Adult LacZ: LacZ Images Wholemount
22 Images
X-ray: XRay Images Dorso Ventral
10 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Marveld2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Marveld2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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