Phenotype | System | Allele | Zyg | Sex | Life Stage | P Value |
---|---|---|---|---|---|---|
enlarged heart | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 0.00 | ||
abnormal auditory brainstem response | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 2.81×10-06 | ||
abnormal urinary bladder morphology | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 0.00 | ||
increased lung weight | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 2.74×10-05 | ||
abnormal eye morphology | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 0.00 | ||
abnormal coat/hair pigmentation | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 4.08×10-06 | ||
increased hematocrit | Tmem30btm1b(EUCOMM)Wtsi | HOM | Early adult | 1.89×10-08 |
Gene: Tmem30b
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IMPC lacZ Expression Data
Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
---|---|---|---|---|---|
Adrenal gland | 3 | No | (3/590) | N/A | |
Aorta | 3 | No | (1/590) | N/A | |
Blood | 3 | No | N/A | ||
Bone marrow | 3 | No | N/A | ||
Brain | 3 | No | (3/590) | N/A | |
Brainstem | 3 | No | (2/590) | N/A | |
Brown adipose tissue | 3 | No | N/A | ||
Cartilage tissue | 3 | No | N/A | ||
Cecum | 3 | No | (12/377) | (1/3) | N/A |
Cerebellum | 3 | No | (3/590) | N/A | |
Cerebral cortex | 3 | No | (2/590) | N/A | |
Chest bone | 3 | No | N/A | ||
Colon | 3 | No | (12/127) | (1/3) | N/A |
Diaphragm | 3 | No | N/A | ||
Duodenum | 3 | No | (2/127) | (1/3) | N/A |
Epididymis | 3 | No | (18/134) | (2/3) | Section images |
Esophagus | 3 | No | (7/415) | N/A | |
Eye | 3 | No | N/A | ||
Gall bladder | 3 | No | N/A | ||
Gonadal fat pad | 3 | No | N/A | ||
Harderian gland | 3 | No | N/A | ||
Heart | 3 | No | (1/590) | N/A | |
Hindlimb | 3 | No | N/A | ||
Hippocampus | 3 | No | (3/590) | N/A | |
Hypothalamus | 3 | No | (2/590) | N/A | |
Ileum | 3 | No | (14/127) | (1/3) | Section images |
Jejunum | 3 | No | (6/127) | N/A | |
Kidney | 3 | No | (20/590) | (3/3) | Wholemount images Section images |
Large intestine | 3 | No | (10/590) | N/A | |
Liver | 3 | No | (1/3) | Wholemount images | |
Lower urinary tract | 3 | No | (1/590) | N/A | |
Lung | 3 | No | (1/590) | N/A | |
Lymph node | 3 | No | N/A | ||
Mammary gland | 3 | No | N/A | ||
Mesenteric adipose tissue | 3 | No | N/A | ||
Mesenteric lymph node | 3 | No | N/A | ||
Midbrain | 3 | No | N/A | ||
Olfactory lobe | 3 | No | (2/590) | N/A | |
Ovary | 3 | No | (1/590) | N/A | |
Oviduct | 3 | No | N/A | ||
Pancreas | 3 | No | (5/590) | N/A | |
Parathyroid gland | 3 | No | (1/3) | Section images | |
Parotid gland | 3 | No | N/A | ||
Penis | 3 | No | (1/3) | Section images | |
Peripheral nervous system | 3 | No | (1/590) | N/A | |
Peyer's patch | 3 | No | N/A | ||
Pituitary gland | 3 | No | (1/590) | (1/3) | Wholemount images |
Prostate gland | 3 | No | (12/590) | N/A | |
Quadriceps | 3 | No | N/A | ||
Sciatic nerve | 3 | No | N/A | ||
Skeletal muscle | 3 | No | N/A | ||
Skin | 3 | No | N/A | ||
Small intestine | 3 | No | (9/590) | N/A | |
Spinal cord | 3 | No | (2/590) | N/A | |
Spleen | 3 | No | (2/590) | N/A | |
Stomach | 3 | No | (13/590) | (1/3) | N/A |
Stomach pyloric region | 3 | No | N/A | ||
Striatum | 3 | No | (3/590) | N/A | |
Sublingual gland | 3 | No | N/A | ||
Submandibular gland | 3 | No | (2/132) | (1/3) | Section images |
Testis | 3 | No | (5/590) | (1/3) | Section images |
Thymus | 3 | No | N/A | ||
Thyroid gland | 3 | No | (16/590) | (1/3) | Wholemount images |
Tongue | 3 | No | (5/127) | N/A | |
Trachea | 3 | No | (2/590) | N/A | |
Trigeminal V nerve | 3 | No | N/A | ||
Urinary bladder | 3 | No | N/A | ||
Uterus | 3 | No | N/A | ||
Vagina | 3 | No | N/A | ||
Vas deferens | 3 | No | (15/388) | (2/3) | Section images |
Vascular system | 3 | No | N/A | ||
Vesicular gland | 3 | No | N/A | ||
White adipose tissue | 3 | No | N/A |
LacZ Wholemount Images
LacZ Section Images
Associated Images
Disease Models
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MGI Allele | Allele Type | Produced |
---|---|---|
Tmem30btm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (post-Cre) | Mice, Tissue |
Tmem30btm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Mice, Targeting vectors, ES Cells |
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