Gene: Gtf2b

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Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Gtf2btm1b(EUCOMM)Wtsi HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Gtf2btm1b(EUCOMM)Wtsi HOM E12.5 0.00
hypoactivity Gtf2btm1b(EUCOMM)Wtsi HET Early adult 5.35×10-05
preweaning lethality, complete penetrance Gtf2btm1b(EUCOMM)Wtsi HOM Early adult 0.00
short tibia Gtf2btm1b(EUCOMM)Wtsi HET Early adult 4.02×10-06

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Select physiological systems to view:
Viewing: all phenotypes


IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 7  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 7  (1/504) N/A
Embryo 7  (1/505) N/A
Eye 7  (1/504) N/A
Foot 7  (1/504) N/A
Forebrain 7  (1/504) N/A
Forelimb 7  (1/504) N/A
Gut 2  (1/56) N/A
Hand 7  (1/503) N/A
Head 7  (5/504) N/A
Heart 7  (1/504) N/A
Hindbrain 7  (6/504) N/A
Hindlimb 7  (1/503) N/A
Liver 7  (1/504) N/A
Lung 7  (1/500) N/A
Mandibular process 7  (1/504) N/A
Maxillary process 7  (1/504) N/A
Midbrain 7  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 7  (1/504) N/A
Skeleton 2  (1/70) N/A
Skin 7  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 7  (1/504) N/A
Tail somite 7  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
28 Images
Eye Morphology: Images Ophthalmoscopy
15 Images
2 Images
Gross Pathology and Tissue Collection
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental and structural abnormality Gtf2btm1b(EUCOMM)Wtsi HET Early adult

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MGI Allele Allele Type Produced
Gtf2btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Gtf2btm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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