Gene: Gtf2b

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Gtf2btm1b(EUCOMM)Wtsi HET Early adult 5.35×10-05
embryonic lethality prior to organogenesis Gtf2btm1b(EUCOMM)Wtsi HOM E9.5 0.00
preweaning lethality, complete penetrance Gtf2btm1b(EUCOMM)Wtsi HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Gtf2btm1b(EUCOMM)Wtsi HOM E12.5 0.00
short tibia Gtf2btm1b(EUCOMM)Wtsi HET Early adult 4.02×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 7  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 7  (1/504) N/A
Embryo 7  (1/505) N/A
Eye 7  (1/504) N/A
Foot 7  (1/504) N/A
Forebrain 7  (1/504) N/A
Forelimb 7  (1/504) N/A
Gut 2  (1/56) N/A
Hand 7  (1/503) N/A
Head 7  (5/504) N/A
Heart 7  (1/504) N/A
Hindbrain 7  (6/504) N/A
Hindlimb 7  (1/503) N/A
Liver 7  (1/504) N/A
Lung 7  (1/500) N/A
Mandibular process 7  (1/504) N/A
Maxillary process 7  (1/504) N/A
Midbrain 7  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 7  (1/504) N/A
Skeleton 2  (1/70) N/A
Skin 7  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 7  (1/504) N/A
Tail somite 7  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
15 Images
Embryo LacZ: LacZ images wholemount
28 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
Histopathology
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental and structural abnormality Gtf2btm1b(EUCOMM)Wtsi HET Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Gtf2btm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Gtf2btm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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