Sbno1 | strawberry notch 1

GeneMGI:2384298Synonyms: 9330180L10Rik, sno

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Immune system Integument Hematopoietic system Mortality/aging

11 No significant impact

7 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetSbno1tm1b(EUCOMM)HmguhomozygoteE12.5N/A * 
abnormal coat appearance1 supporting datasetSbno1tm1b(EUCOMM)HmguheterozygoteEarly adult5.3x10-6 
increased circulating fructosamine level1 supporting datasetSbno1tm1b(EUCOMM)HmguheterozygoteEarly adult5.25x10-5 
increased leukocyte cell number1 supporting datasetSbno1tm1b(EUCOMM)HmguheterozygoteEarly adult4.72x10-5 
embryonic lethality prior to organogenesis1 supporting datasetSbno1tm1b(EUCOMM)HmguhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetSbno1tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased red blood cell distribution width1 supporting datasetSbno1tm1b(EUCOMM)HmguheterozygoteEarly adult2.7x10-5 
abnormal coat/hair pigmentation1 supporting datasetSbno1tm1b(EUCOMM)HmguheterozygoteEarly adult1.59x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sbno1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Sbno1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Sbno1tm300560(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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