Rxfp2 - relaxin/insulin-like family peptide receptor 2 | International Mouse Phenotyping Consortium

Genes Phenotypes

Gene: Rxfp2

Phenotype	Allele	Zyg	Life Stage	P Value
urinary bladder obstruction	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	0.00
abnormal liver morphology	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	0.00
increased circulating alkaline phosphatase level	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	1.26×10^-07
decreased body weight	Rxfp2^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	2.22×10^-05
abnormal lens morphology	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	2.01×10^-09
increased circulating calcium level	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	1.27×10^-05
increased circulating chloride level	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	8.14×10^-05
decreased IgE level	Rxfp2^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	2.59×10^-06
abnormal behavior	Rxfp2^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	1.92×10^-05
small testis	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	0.00
hypoactivity	Rxfp2^{tm1a(EUCOMM)Wtsi}	HOM	postnatal	6.45×10^-05
abnormal optic disk morphology	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	8.52×10^-06
male infertility	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postpartum stage	0.00
increased circulating sodium level	Rxfp2^{tm1b(EUCOMM)Wtsi}	HOM	postnatal	4.89×10^-06

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Filtered by: all phenotypes

Table Images

Expression No Expression Ambiguous No Tissue Available

Anatomy	#HET Specimens	HOM Images?	WT Expr	Mutant Expr	Images
Adrenal gland	1	No	(2/584)		N/A
Aorta	1	No			N/A
Blood	1	No			N/A
Bone	1	No			N/A
Bone marrow	1	No			N/A
Brain	1	No			N/A
Brainstem	1	No			N/A
Brown adipose tissue	1	No			N/A
Cartilage tissue	1	No			N/A
Cecum	1	No	(12/383)		N/A
Cerebellum	1	No			N/A
Cerebral cortex	1	No			N/A
Chest bone	1	No			N/A
Colon	1	No	(12/127)		N/A
Cranium	1	No			N/A
Diaphragm	1	No			N/A
Epididymis	1	No	(18/134)		N/A
Esophagus	1	No	(7/415)		N/A
Eye	1	No			N/A
Gall bladder	1	No			N/A
Harderian gland	1	No			N/A
Heart	1	No			N/A
Hindlimb	1	No			N/A
Hippocampus	1	No			N/A
Hypothalamus	1	No			N/A
Kidney	1	No	(18/584)		N/A
Large intestine	1	No	(10/584)		N/A
Liver	1	No			N/A
Lower urinary tract	1	No			N/A
Lung	1	No			N/A
Lymph node	1	No			N/A
Main olfactory bulb	1	No			N/A
Mammary gland	1	No			N/A
Mesenteric lymph node	1	No			N/A
Olfactory lobe	1	No			N/A
Oral epithelium	1	No			N/A
Ovary	1	No	(1/584)		N/A
Oviduct	1	No			N/A
Pancreas	1	No	(5/584)		N/A
Parathyroid gland	1	No			N/A
Parotid gland	1	No			N/A
Penis	1	No			N/A
Peripheral nervous system	1	No			N/A
Peyer's patch	1	No			N/A
Pituitary gland	1	No			N/A
Prostate gland	1	No	(12/584)		N/A
Sciatic nerve	1	No			N/A
Skeletal muscle	1	No			N/A
Skin	1	No			N/A
Small intestine	1	No	(9/584)		N/A
Spinal cord	1	No			N/A
Spleen	1	No	(2/584)		N/A
Stomach	1	No	(12/584)		N/A
Stomach pyloric region	1	No			N/A
Striatum	1	No			N/A
Sublingual gland	1	No			N/A
Submandibular gland	1	No	(2/132)		N/A
Testis	1	No	(2/584)	(1/1)	Wholemount images
Thymus	1	No			N/A
Thyroid gland	1	No	(15/584)		N/A
Tongue	1	No	(5/127)		N/A
Trachea	1	No			N/A
Trigeminal V nerve	1	No			N/A
Urinary bladder	1	No			N/A
Uterus	1	No			N/A
Vagina	1	No			N/A
Vas deferens	1	No	(15/388)		N/A
Vascular system	1	No			N/A
Vesicular gland	1	No			N/A
White adipose tissue	1	No			N/A

postnatal mouse (1)
Testis expression
MA:0000411

reproductive system (1)
Testis expression
MA:0000411

trunk (1)
Testis expression
MA:0000411

No Embryo expression data was found for this gene.

X-ray: XRay Images Lateral Orientation
9 Images

X-ray: XRay Images Dorso Ventral
9 Images

Adult LacZ: LacZ Images Wholemount
1 Images

No associations by disease annotation and gene orthology found.

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MGI Allele	Allele Type	Availability
Rxfp2^{tm1a(EUCOMM)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells
Rxfp2^{tm1b(EUCOMM)Wtsi}	Reporter-tagged deletion allele (post-Cre)	Mice
Rxfp2^{tm39993(L1L2_st1)}		Targeting vectors