Genes Phenotypes

Gene: Rxfp2

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Name
relaxin/insulin-like family peptide receptor 2
MGI ID
MGI:2153463
Synonyms
Great Gpr106 LGR8
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (14) Measurements chart (500) All data table (724)
Expression & images (70) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
hypoactivity Rxfp2tm1a(EUCOMM)Wtsi HOM postnatal 6.45×10-05
abnormal optic disk morphology Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 8.52×10-06
male infertility Rxfp2tm1b(EUCOMM)Wtsi HOM postpartum stage 0.00
increased circulating sodium level Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 4.89×10-06
increased circulating alkaline phosphatase level Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 1.26×10-07
decreased body weight Rxfp2tm1a(EUCOMM)Wtsi HOM postnatal 2.22×10-05
urinary bladder obstruction Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 0.00
abnormal lens morphology Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 2.01×10-09
increased circulating calcium level Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 1.27×10-05
increased circulating chloride level Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 8.14×10-05
small testis Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 0.00
abnormal liver morphology Rxfp2tm1b(EUCOMM)Wtsi HOM postnatal 0.00
decreased IgE level Rxfp2tm1a(EUCOMM)Wtsi HOM postnatal 2.59×10-06
abnormal behavior Rxfp2tm1a(EUCOMM)Wtsi HOM postnatal 1.92×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 1 No  (2/584) N/A
Aorta 1 No N/A
Blood 1 No N/A
Bone 1 No N/A
Bone marrow 1 No N/A
Brain 1 No N/A
Brainstem 1 No N/A
Brown adipose tissue 1 No N/A
Cartilage tissue 1 No N/A
Cecum 1 No  (12/383) N/A
Cerebellum 1 No N/A
Cerebral cortex 1 No N/A
Chest bone 1 No N/A
Colon 1 No  (12/127) N/A
Cranium 1 No N/A
Diaphragm 1 No N/A
Epididymis 1 No  (18/134) N/A
Esophagus 1 No  (7/415) N/A
Eye 1 No N/A
Gall bladder 1 No N/A
Harderian gland 1 No N/A
Heart 1 No N/A
Hindlimb 1 No N/A
Hippocampus 1 No N/A
Hypothalamus 1 No N/A
Kidney 1 No  (18/584) N/A
Large intestine 1 No  (10/584) N/A
Liver 1 No N/A
Lower urinary tract 1 No N/A
Lung 1 No N/A
Lymph node 1 No N/A
Main olfactory bulb 1 No N/A
Mammary gland 1 No N/A
Mesenteric lymph node 1 No N/A
Olfactory lobe 1 No N/A
Oral epithelium 1 No N/A
Ovary 1 No  (1/584) N/A
Oviduct 1 No N/A
Pancreas 1 No  (5/584) N/A
Parathyroid gland 1 No N/A
Parotid gland 1 No N/A
Penis 1 No N/A
Peripheral nervous system 1 No N/A
Peyer's patch 1 No N/A
Pituitary gland 1 No N/A
Prostate gland 1 No  (12/584) N/A
Sciatic nerve 1 No N/A
Skeletal muscle 1 No N/A
Skin 1 No N/A
Small intestine 1 No  (9/584) N/A
Spinal cord 1 No N/A
Spleen 1 No  (2/584) N/A
Stomach 1 No  (12/584) N/A
Stomach pyloric region 1 No N/A
Striatum 1 No N/A
Sublingual gland 1 No N/A
Submandibular gland 1 No  (2/132) N/A
Testis 1 No  (2/584)  (1/1)  Wholemount images
Thymus 1 No N/A
Thyroid gland 1 No  (15/584) N/A
Tongue 1 No  (5/127) N/A
Trachea 1 No N/A
Trigeminal V nerve 1 No N/A
Urinary bladder 1 No N/A
Uterus 1 No N/A
Vagina 1 No N/A
Vas deferens 1 No  (15/388) N/A
Vascular system 1 No N/A
Vesicular gland 1 No N/A
White adipose tissue 1 No N/A
LacZ Wholemount Images
postnatal mouse (1)
Testis expression
MA:0000411
reproductive system (1)
Testis expression
MA:0000411
trunk (1)
Testis expression
MA:0000411
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rxfp2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rxfp2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Rxfp2tm39993(L1L2_st1) Targeting vectors