Trim66 | tripartite motif-containing 66

GeneMGI:2152406Synonyms: Tif1d, D7H11orf29

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological Cardiovascular system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetTrim66tm1a(EUCOMM)WtsihomozygoteEarly adult2.9x10-6 
decreased body weight2 supporting datasetsTrim66tm1a(EUCOMM)WtsihomozygoteEarly adult5.77x10-5 
increased heart weight1 supporting datasetTrim66tm1a(EUCOMM)WtsihomozygoteEarly adult2.2x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trim66tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Trim66tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Trim66tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Trim66tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Trim66tm47408(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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