Genes Phenotypes

Gene: Usp22

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Name
ubiquitin specific peptidase 22
MGI ID
MGI:2144157
Synonyms
N/A
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (417) All data table (815)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Usp22tm1a(KOMP)Wtsi HOM Early adult 0.00
abnormal gait Usp22tm1b(KOMP)Wtsi HET Early adult 8.32×10-07
prenatal lethality prior to heart atrial septation Usp22tm1a(KOMP)Wtsi HOM E15.5 0.00
preweaning lethality, complete penetrance Usp22tm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Usp22tm1b(KOMP)Wtsi HOM E12.5 0.00
decreased lean body mass Usp22tm1b(KOMP)Wtsi HET Early adult 4.14×10-05
decreased mean platelet volume Usp22tm1b(KOMP)Wtsi HET Early adult 4.02×10-05

Download data as:  TSV  XLS

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (2)
Aorta expression
Heart expression
MA:0000062
MA:0000072
digestive system (5)
Gall Bladder expression
MA:0000356
endocrine system (2)
Adrenal gland expression
MA:0000116
exocrine system (1)
Prostate gland expression
Lower Urinary Tract expression
MA:0000404
MA:0002636
integumental system (1)
Skin expression
MA:0000151
musculoskeletal system (1)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
nervous system (5)
Olfactory Lobe expression
Cerebral Cortex expression
Striatum expression
Hippocampus expression
Hypothalamus expression
Cerebellum expression
Brainstem expression
Brain expression
MA:0002413
MA:0000185
MA:0000891
MA:0000191
MA:0000173
MA:0000198
MA:0000169
MA:0000168
postnatal mouse (22)
Adrenal gland expression
MA:0000116
reproductive system (3)
Ovary expression
Oviduct expression
Uterus expression
MA:0000384
MA:0000385
MA:0000389
respiratory system (2)
Cartilage tissue expression
Trachea expression
Thyroid gland ambiguous
Parathyroid gland expression
MA:0000104
MA:0000441
MA:0000129
MA:0000128
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
trunk (13)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (3/3) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (3/3) N/A
Eye 2  (1/504)  (3/3) N/A
Foot 2  (1/504) Image Only N/A
Forebrain 2  (1/504)  (3/3) N/A
Forelimb 2  (1/504)  (3/3) N/A
Hand 2  (1/503) Image Only N/A
Head 2  (5/504)  (3/3) N/A
Heart 2  (1/504) Image Only N/A
Hindbrain 2  (6/504)  (3/3) N/A
Hindlimb 2  (1/503)  (3/3) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504)  (3/3) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (3/3) N/A
Tail somite 2  (1/504)  (3/3) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
51 Images
X-ray: XRay Images Whole Body Lateral Orientation
38 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
24 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
22 Images
X-ray: XRay Images Forepaw
13 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Legacy Phenotype Associated Images
Usp22tm1a(KOMP)Wtsi
HET, Female, WTSI
Usp22tm1a(KOMP)Wtsi
HET, Female, WTSI
Usp22tm1a(KOMP)Wtsi
HET, Female, WTSI
Usp22tm1a(KOMP)Wtsi
HET, Female, WTSI
Usp22tm1a(KOMP)Wtsi
HET, Female, WTSI

View all 84 images

Usp22tm1a(KOMP)Wtsi
left eye, WT, Male, WTSI
Usp22tm1a(KOMP)Wtsi
right eye, WT, Male, WTSI
Usp22tm1a(KOMP)Wtsi
back skin, HET, Female, WTSI
Usp22tm1a(KOMP)Wtsi
back skin, HET, Female, WTSI

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Usp22tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Usp22tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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