Gene: Usp22

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, complete penetrance Usp22tm1a(KOMP)Wtsi HOM Early adult 0.00
abnormal gait Usp22tm1b(KOMP)Wtsi HET Early adult 8.32×10-07
prenatal lethality prior to heart atrial septation Usp22tm1a(KOMP)Wtsi HOM E15.5 0.00
preweaning lethality, complete penetrance Usp22tm1b(KOMP)Wtsi HOM Early adult 0.00
embryonic lethality prior to tooth bud stage Usp22tm1b(KOMP)Wtsi HOM E12.5 0.00
decreased lean body mass Usp22tm1b(KOMP)Wtsi HET Early adult 4.14×10-05
decreased mean platelet volume Usp22tm1b(KOMP)Wtsi HET Early adult 4.02×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No  (2/2)  Wholemount images
Hypothalamus 2 No  (2/2)  Wholemount images
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Wholemount images
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/584)  (2/2)  Wholemount images
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  Wholemount images
Trachea 2 No  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (3/3) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (3/3) N/A
Eye 2  (1/504)  (3/3) N/A
Foot 2  (1/504) Image Only N/A
Forebrain 2  (1/504)  (3/3) N/A
Forelimb 2  (1/504)  (3/3) N/A
Hand 2  (1/503) Image Only N/A
Head 2  (5/504)  (3/3) N/A
Heart 2  (1/504) Image Only N/A
Hindbrain 2  (6/504)  (3/3) N/A
Hindlimb 2  (1/503)  (3/3) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504)  (3/3) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (3/3) N/A
Tail somite 2  (1/504)  (3/3) N/A

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Whole Body Dorso Ventral
51 Images
X-ray: XRay Images Whole Body Lateral Orientation
38 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
24 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
22 Images
X-ray: XRay Images Forepaw
13 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Legacy Phenotype Associated Images

View all 84 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Usp22tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Usp22tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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