Gene: Usp22

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
thrombocytosis Usp22tm1a(KOMP)Wtsi HET Early adult 8.01×10-05
preweaning lethality, complete penetrance Usp22tm1b(KOMP)Wtsi HOM Early adult 0.00
decreased grip strength Usp22tm1a(KOMP)Wtsi HET Early adult 1.91×10-05
abnormal PQ interval Usp22tm1b(KOMP)Wtsi HET Early adult 8.00×10-05
preweaning lethality, complete penetrance Usp22tm1a(KOMP)Wtsi HOM Early adult 0.00
decreased circulating insulin level Usp22tm1a(KOMP)Wtsi HET Early adult 8.21×10-06
abnormal gait Usp22tm1b(KOMP)Wtsi HET Early adult 7.37×10-07
abnormal PR interval Usp22tm1b(KOMP)Wtsi HET Early adult 2.56×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (2/2)  Wholemount images
Aorta 2 No  (1/589)  (2/2)  Wholemount images
Bone 2 No  (2/2)  Wholemount images
Brain 2 No  (3/589)  (2/2)  Wholemount images
Brainstem 2 No  (2/589)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Wholemount images
Cerebellum 2 No  (3/589)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/589)  (2/2)  Wholemount images
Esophagus 2 No  (7/415)  (2/2)  Wholemount images
Eye 2 No  (2/2)  Wholemount images
Gall bladder 2 No  (2/2)  Wholemount images
Heart 2 No  (1/589)  (2/2)  Wholemount images
Hippocampus 2 No  (3/589)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/589)  (2/2)  Wholemount images
Kidney 2 No  (20/589)  (2/2)  Wholemount images
Large intestine 2 No  (10/589)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/589)  (2/2)  Wholemount images
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/589)  (2/2)  Wholemount images
Oral epithelium 2 No  (1/2)  Wholemount images
Ovary 2 No  (1/589)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/589)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/589)  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  (2/2)  Wholemount images
Prostate gland 2 No  (12/589)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Wholemount images
Small intestine 2 No  (9/589)  (2/2)  Wholemount images
Spinal cord 2 No  (2/589)  (2/2)  Wholemount images
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589)  (2/2)  Wholemount images
Striatum 2 No  (3/589)  (2/2)  Wholemount images
Testis 2 No  (5/589)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/589)  Wholemount images
Trachea 2 No  (2/589)  (2/2)  Wholemount images
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (3/3) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (3/3) N/A
Eye 2  (1/506)  (3/3) N/A
Foot 2  (1/506) Image Only N/A
Forebrain 2  (1/506)  (3/3) N/A
Forelimb 2  (1/506)  (3/3) N/A
Hand 2  (1/505) Image Only N/A
Head 2  (5/506)  (3/3) N/A
Heart 2  (1/506) Image Only N/A
Hindbrain 2  (6/506)  (3/3) N/A
Hindlimb 2  (1/505)  (3/3) N/A
Liver 2  (1/506) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506)  (3/3) N/A
Oral cavity 2  (1/506) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506)  (3/3) N/A
Tail somite 2  (1/506)  (3/3) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
53 Images
X-ray: XRay Images Whole Body Lateral Orientation
38 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
24 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
51 Images
Echo: M-Mode Images
32 Images
X-ray: XRay Images Forepaw
13 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Legacy Phenotype Associated Images

View all 84 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Usp22tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Usp22tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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