AU040320 | expressed sequence AU040320

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Reproductive system Pigmentation Integument Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:14Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetAU040320em1(IMPC)JhomozygoteEarly adult2.37x10-5 
abnormal retina morphology1 supporting datasetAU040320em1(IMPC)JhomozygoteLate adult8.64x10-12 
hyperactivity6 supporting datasetsAU040320em1(IMPC)JhomozygoteLate adult2.26x10-9 
hyperactivity5 supporting datasetsAU040320em1(IMPC)JhomozygoteEarly adult6.27x10-7 
decreased grip strength2 supporting datasetsAU040320em1(IMPC)JhomozygoteLate adult1.13x10-9 
limb grasping1 supporting datasetAU040320em1(IMPC)JhomozygoteLate adult3.28x10-7 
decreased bone mineral content2 supporting datasetsAU040320em1(IMPC)JhomozygoteEarly adult4.5x10-6 
increased exploration in new environment1 supporting datasetAU040320em1(IMPC)JhomozygoteLate adult2.28x10-9 
absent vibrissae1 supporting datasetAU040320em1(IMPC)JhomozygoteLate adult1.74x10-5 
abnormal retina morphology1 supporting datasetAU040320em1(IMPC)JhomozygoteEarly adult4.19x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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AU040320em1(IMPC)JExon Deletionmouse
AU040320tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
AU040320tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
AU040320tm497(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
AU040320tm497(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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