Tmem237 | transmembrane protein 237

GeneMGI:2138365Synonyms: Als2cr4, LOC381259

Physiological systems

20 / 24 physiological systems tested

13 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Skeleton Mortality/aging Cardiovascular system

7 No significant impact

4 Not tested

Gene metrics:23Significant phenotypes
5Associated diseases
Expression examined in:78Adult tissues
36Embryo tissues

Phenotypes

abnormal testis morphology1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
abnormal adrenal gland morphology1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
abnormal brain morphology2 supporting datasetsTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
increased circulating triglyceride level1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adult3.99x10-37 
increased circulating calcium level1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adult6.75x10-9 
enlarged heart2 supporting datasetsTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
abnormal heart morphology2 supporting datasetsTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
small testis1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adultN/A * 
increased circulating aspartate transaminase level1 supporting datasetTmem237tm1b(EUCOMM)HmguheterozygoteEarly adult3.73x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  
Rows per page: 










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Tmem237tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Tmem237tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Tmem237tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter