Ift122 | intraflagellar transport 122
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Mortality/aging
14 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
long tibia | 1 supporting dataset | Ift122tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.49x10-6 | ||
decreased locomotor activity | 1 supporting dataset | Ift122tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 4.06x10-6 | ||
increased circulating aspartate transaminase level | 1 supporting dataset | Ift122tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.85x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Ift122tm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
increased mean corpuscular volume | 1 supporting dataset | Ift122tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 2.65x10-7 | ||
abnormal behavior | 1 supporting dataset | Ift122tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.52x10-6 |
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External links
No external links available for Ift122.
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Ift122tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Ift122tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |