Gene: Coq6

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal vitreous body morphology Coq6tm1b(EUCOMM)Hmgu HET Early adult 1.09×10-06
increased circulating sodium level Coq6tm1b(EUCOMM)Hmgu HET Early adult 2.76×10-06
abnormal tail bud morphology Coq6tm1b(EUCOMM)Hmgu HOM E9.5 0.00
embryonic lethality prior to tooth bud stage Coq6tm1b(EUCOMM)Hmgu HOM E12.5 0.00
abnormal embryo size Coq6tm1b(EUCOMM)Hmgu HOM E9.5 0.00
preweaning lethality, complete penetrance Coq6tm1b(EUCOMM)Hmgu HOM Early adult 0.00
abnormal neural tube closure Coq6tm1b(EUCOMM)Hmgu HOM E9.5 0.00
persistence of hyaloid vascular system Coq6tm1b(EUCOMM)Hmgu HET Early adult 5.21×10-06
abnormal embryo turning Coq6tm1b(EUCOMM)Hmgu HET E9.5 0.00
abnormal embryo size Coq6tm1b(EUCOMM)Hmgu HET E9.5 0.00
abnormal embryo turning Coq6tm1b(EUCOMM)Hmgu HOM E9.5 0.00
abnormal tail bud morphology Coq6tm1b(EUCOMM)Hmgu HET E9.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589) N/A
Aorta 2 No  (1/589) N/A
Brain 2 No  (3/589) N/A
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/589) N/A
Cerebral cortex 2 No  (2/589) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No  (1/589) N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Kidney 2 No  (20/589)  (2/2)  Section images
Large intestine 2 No  (10/589) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No  (2/589) N/A
Ovary 2 No  (1/589)  Section images
Oviduct 2 No N/A
Pancreas 2 No  (5/589) N/A
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589) N/A
Prostate gland 2 No  (12/589) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589) N/A
Spleen 2 No  (2/589) N/A
Stomach 2 No  (13/589) N/A
Striatum 2 No  (3/589) N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/589)  (1/2)  Section images
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/589) N/A
Trachea 2 No  (2/589) N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/506) N/A
Dorsal root ganglion 1  (1/61) N/A
Ear 1  (1/506) N/A
Embryo 1  (1/507) N/A
Eye 1  (1/506) N/A
Foot 1  (1/506) N/A
Forebrain 1  (1/506) N/A
Forelimb 1  (1/506) N/A
Fronto-nasal process 1  (1/62) N/A
Hand 1  (1/505) N/A
Head 1  (5/506) N/A
Heart 1  (1/506) N/A
Hindbrain 1  (6/506) N/A
Hindlimb 1  (1/505) N/A
Liver 1  (1/506) N/A
Lung 1  (1/502) N/A
Mandibular process 1  (1/506) N/A
Maxillary process 1  (1/506) N/A
Midbrain 1  (1/506) N/A
Nose 1  (1/74) N/A
Oral cavity 1  (1/506) N/A
Skin 1  (1/506) N/A
Spinal cord 1  (1/73) N/A
Tail 1  (1/506) N/A
Tail somite 1  (1/506) N/A

 Associated Images

Immunophenotyping: Panel B FCS file(s)
6 Images
X-ray: XRay Images Whole Body Dorso Ventral
21 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
Adult LacZ: LacZ Images Section
4 Images
X-ray: XRay Images Forepaw
11 Images
Eye Morphology: Images Ophthalmoscopy
8 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
21 Images
Immunophenotyping: Panel A FCS file(s)
6 Images
Sleep Wake: Wake state (bmp file)
2 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Coq6tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Coq6tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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