Gene: Coq6

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal embryo size Coq6tm1b(EUCOMM)Hmgu HOM embryonic day 9.5 0.00
preweaning lethality, complete penetrance Coq6tm1b(EUCOMM)Hmgu HOM n/a 0.00
abnormal tail bud morphology Coq6tm1b(EUCOMM)Hmgu HOM embryonic day 9.5 0.00
abnormal embryo turning Coq6tm1b(EUCOMM)Hmgu HOM embryonic day 9.5 0.00
embryonic lethality prior to tooth bud stage Coq6tm1b(EUCOMM)Hmgu HOM embryonic day 12.5 0.00
abnormal embryo turning Coq6tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
abnormal cornea morphology Coq6tm1b(EUCOMM)Hmgu HET postnatal 2.24×10-05
abnormal neural tube closure Coq6tm1b(EUCOMM)Hmgu HOM embryonic day 9.5 0.00
embryonic growth retardation Coq6tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
increased circulating sodium level Coq6tm1b(EUCOMM)Hmgu HET postnatal 4.74×10-07
abnormal vitreous body morphology Coq6tm1b(EUCOMM)Hmgu HET postnatal 1.07×10-05
abnormal embryo size Coq6tm1b(EUCOMM)Hmgu HET embryonic day 9.5 0.00
embryonic growth retardation Coq6tm1b(EUCOMM)Hmgu HOM embryonic day 9.5 0.00
persistence of hyaloid vascular system Coq6tm1b(EUCOMM)Hmgu HET postnatal 1.78×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/485) N/A
Dorsal root ganglion 1  (1/47) N/A
Ear 1  (1/485) N/A
Embryo 1  (1/485) N/A
Eye 1  (1/485) N/A
Foot 1  (1/485) N/A
Forebrain 1  (1/485) N/A
Forelimb 1  (1/485) N/A
Fronto-nasal process 1  (1/48) N/A
Hand 1  (1/485) N/A
Head 1  (5/485) N/A
Heart 1  (1/485) N/A
Hindbrain 1  (6/485) N/A
Hindlimb 1  (1/485) N/A
Liver 1  (1/485) N/A
Lung 1  (1/485) N/A
Mandibular process 1  (1/485) N/A
Maxillary process 1  (1/485) N/A
Midbrain 1  (1/485) N/A
Nose 1  (1/51) N/A
Oral cavity 1  (1/485) N/A
Skin 1  (1/485) N/A
Spinal cord 1  (1/50) N/A
Tail 1  (1/485) N/A
Tail somite 1  (1/485) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
21 Images
X-ray: XRay Images Lateral Orientation
21 Images
X-ray: XRay Images Forepaw
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Sleep Wake: Wake state (bmp file)
2 Images
Electroretinography 2: Rod and cone PDF
4 Images
Gross Morphology Embryo E9.5
4 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Coq6tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Coq6tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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