Ppil1 | peptidylprolyl isomerase (cyclophilin)-like 1
Physiological systems
21 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Mortality/aging Renal/urinary system
12 No significant impact
3 Not tested
Data collections
Gene metrics:11Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal skin morphology | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
polycystic kidney | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
decreased exploration in new environment | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | 7.49x10-5 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Ppil1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
small kidney | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal kidney morphology | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | 2.94x10-5 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Ppil1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
increased circulating creatinine level | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | 1.34x10-6 | ||
microphthalmia | 1 supporting dataset | Ppil1em1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ppil1.
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Ppil1em1(IMPC)Mbp | Exon Deletion | | mouse |
Ppil1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Ppil1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |