Gene: Sdha

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Name
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
MGI ID
MGI:1914195
Synonyms
SDHF SDH2 FP 2310034D06Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Sdhatm2b(KOMP)Wtsi HOM   E9.5 0.00
increased circulating sodium level Sdhatm2b(KOMP)Wtsi HET Early adult 5.84×10-06
abnormal tooth morphology Sdhatm2b(KOMP)Wtsi HET   Early adult 9.72×10-05
increased circulating free fatty acids level Sdhatm2b(KOMP)Wtsi HET   Early adult 5.65×10-05
decreased circulating glucose level Sdhatm2b(KOMP)Wtsi HET Early adult 1.21×10-05
preweaning lethality, complete penetrance Sdhatm2b(KOMP)Wtsi HOM   Early adult 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584)  (2/2)  Section images
Aorta 2 No  (1/584)  (2/2)  Section images
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (4/584)  (2/2)  Section images
Brainstem 2 No  (2/584)  (2/2)  Section images
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No  (1/584)  (2/2)  Section images
Cerebellum 2 No  (3/584)  (2/2)  Section images
Cerebral cortex 2 No  (2/584)  (2/2)  Section images
Epididymis 2 No  (17/133)  (1/2)  Section images
Esophagus 2 No  (7/408)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/584)  (2/2)  Section images
Hippocampus 2 No  (3/584)  (2/2)  Section images
Hypothalamus 2 No  (2/584)  (2/2)  Section images
Kidney 2 No  (21/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/584) N/A
Lung 2 No  (2/584)  (2/2)  Section images
Lymph node 2 No  (1/584)  (2/2)  Section images
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/584)  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/584)  (2/2)  Section images
Peyer's patch 2 No  (2/2)  Section images
Pituitary gland 2 No  (1/584)  (1/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2)  Section images
Skin 2 No  (1/584)  (2/2)  Section images
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (3/584)  (2/2)  Section images
Spleen 2 No  (3/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (3/584)  (2/2)  Section images
Submandibular gland 2 No  (2/131)  (2/2)  Section images
Testis 2 No  (6/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (1/584)  (2/2)  Section images
Thyroid gland 2 No  (16/584)  (2/2)  Section images
Trachea 2 No  (3/584)  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2)  Section images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/507)  (1/1) N/A
Ear 1  (1/507) N/A
Embryo 1  (1/508)  (1/1)  Wholemount images
Eye 1  (1/507)  (1/1) N/A
Footplate 1  (1/507)  (1/1) N/A
Forebrain 1  (1/507)  (1/1) N/A
Forelimb 1  (1/507)  (1/1) N/A
Handplate 1  (1/507)  (1/1) N/A
Head 1  (5/507)  (1/1) N/A
Heart 1  (1/507)  (1/1) N/A
Hindbrain 1  (6/507)  (1/1) N/A
Hindlimb 1  (1/507)  (1/1) N/A
Liver 1  (1/502) N/A
Lung 1  (1/502) N/A
Mandibular process 1  (1/507)  (1/1) N/A
Maxillary process 1  (1/507)  (1/1) N/A
Midbrain 1  (1/507)  (1/1) N/A
Oral cavity 1  (1/502)  (1/1) N/A
Skin 1  (1/507)  (1/1) N/A
Tail 1  (1/507)  (1/1) N/A
Tail somite group 1  (1/507)  (1/1) N/A

 Associated Images

X-ray: XRay Images Forepaw
11 Images
Original Image
Adult LacZ: LacZ Images Section
46 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
Combined SHIRPA and Dysmorphology
6 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Eye Morphology: Images Slit Lamp
4 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
Embryo LacZ: LacZ images wholemount
4 Images
Sleep Wake: Wake state (bmp file)
1 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sdhatm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sdhatm50282(L1L2_Bact_P) Targeting vectors
Sdhatm2b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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