Gene: Cnot4

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Name
CCR4-NOT transcription complex, subunit 4
MGI ID
MGI:1859026
Synonyms
Not4h Not4 Not4hp
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased total body fat amount Cnot4tm1b(EUCOMM)Wtsi HET Early adult 7.16×10-13
decreased lean body mass Cnot4tm1b(EUCOMM)Wtsi HET Early adult 3.33×10-16
decreased circulating alkaline phosphatase level Cnot4tm1b(EUCOMM)Wtsi HET Early adult 1.50×10-12
decreased bone mineral density Cnot4tm1b(EUCOMM)Wtsi HET Early adult 8.66×10-05
decreased KLRG1-positive NK cell number Cnot4tm1b(EUCOMM)Wtsi HET Early adult 0.00
abnormal bone structure Cnot4tm1b(EUCOMM)Wtsi HET Early adult 4.72×10-14
decreased body length Cnot4tm1b(EUCOMM)Wtsi HET   Early adult 3.15×10-06
preweaning lethality, complete penetrance Cnot4tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
decreased bone mineral content Cnot4tm1b(EUCOMM)Wtsi HET Early adult 3.52×10-21
abnormal epidermal immune compartment Cnot4tm1b(EUCOMM)Wtsi HET   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583)  (2/2) N/A
2 No N/A
2 No N/A
2 No  (4/583)  (2/2) N/A
2 No  (2/583)  (2/2) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583)  (2/2) N/A
2 No  (2/583)  (1/2) N/A
2 No N/A
2 No N/A
2 No  (2/583)  (2/2) N/A
2 No  (3/583)  (2/2) N/A
2 No  (2/583)  (2/2) N/A
2 No  (21/583)  (2/2) N/A
2 No  (10/583) N/A
2 No N/A
2 No  (1/583)  (2/2) N/A
2 No  (2/583)  (2/2) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (1/563) N/A
2 No  (2/583) N/A
2 No  (1/176) N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583)  (2/2) N/A
2 No  (3/583) N/A
2 No  (13/583) N/A
2 No  (3/583)  (2/2) N/A
2 No  (6/583)  (1/2) N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
LacZ Section Images

View all 7 images

View all 6 images

No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
Eye Morphology: Images Slit Lamp
2 Images
Legacy Phenotype Associated Images

View all 105 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Cnot4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Cnot4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cnot4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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