Gene: Cnot4

Log in to follow
CCR4-NOT transcription complex, subunit 4
Not4h Not4 Not4hp
Embryo viewer
Other links
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased body length Cnot4tm1b(EUCOMM)Wtsi HET   Early adult 3.14×10-06
increased total body fat amount Cnot4tm1b(EUCOMM)Wtsi HET Early adult 7.16×10-13
abnormal bone structure Cnot4tm1b(EUCOMM)Wtsi HET Early adult 4.71×10-14
decreased lean body mass Cnot4tm1b(EUCOMM)Wtsi HET Early adult 3.33×10-16
decreased circulating alkaline phosphatase level Cnot4tm1b(EUCOMM)Wtsi HET Early adult 1.50×10-12
decreased bone mineral density Cnot4tm1b(EUCOMM)Wtsi HET Early adult 8.61×10-05
decreased KLRG1-positive NK cell number Cnot4tm1b(EUCOMM)Wtsi HET Early adult 0.00
preweaning lethality, complete penetrance Cnot4tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
abnormal epidermal immune compartment Cnot4tm1b(EUCOMM)Wtsi HET   Early adult 0.00
decreased bone mineral content Cnot4tm1b(EUCOMM)Wtsi HET Early adult 3.52×10-21

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590)  (2/2) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2) N/A
Brainstem 2 No  (2/590)  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590)  (2/2) N/A
Cerebral cortex 2 No  (2/590)  (1/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590)  (2/2) N/A
Hippocampus 2 No  (3/590)  (2/2) N/A
Hypothalamus 2 No  (2/590)  (2/2) N/A
Kidney 2 No  (20/590)  (2/2) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590)  (2/2) N/A
Lung 2 No  (1/590)  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590)  (2/2) N/A
Testis 2 No  (5/590)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Section Images

View all 7 images

View all 6 images

No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Forepaw
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Whole Body Dorso Ventral
14 Images
DSS Histology
8 Images
X-ray: XRay Images Whole Body Lateral Orientation
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
Anti-nuclear antibody assay
6 Images
Eye Morphology: Images Slit Lamp
2 Images
Ear epidermis immunophenotyping
12 Images
Legacy Phenotype Associated Images

View all 105 images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Cnot4tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Cnot4tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Cnot4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter