Gene: Slc25a3

Name
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
MGI ID
MGI:1353498
Synonyms
Phc 5730556H19Rik
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal pharyngeal arch morphology Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal neural tube morphology Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal allantois morphology Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal heart looping Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal tail bud morphology Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
enlarged heart Slc25a3tm1b(EUCOMM)Wtsi HET postnatal 0.00
pale yolk sac Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
embryonic lethality prior to organogenesis Slc25a3tm1b(EUCOMM)Wtsi HOM embryonic day 9.5 0.00
abnormal limb bud morphology Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
abnormal embryo turning Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
preweaning lethality, complete penetrance Slc25a3tm1b(EUCOMM)Wtsi HOM n/a 0.00
pallor Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00
increased blood urea nitrogen level Slc25a3tm1b(EUCOMM)Wtsi HET postnatal 1.87×10-05
abnormal heart morphology Slc25a3tm1b(EUCOMM)Wtsi HET postnatal 0.00
small testis Slc25a3tm1b(EUCOMM)Wtsi HET postnatal 0.00
increased circulating serum albumin level Slc25a3tm1b(EUCOMM)Wtsi HET postnatal 5.28×10-06
abnormal neural tube closure Slc25a3tm1b(EUCOMM)Wtsi HET embryonic day 9.5 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (1/2) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383)  (1/2) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (1/2) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127)  (1/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (1/2) N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127)  (1/2) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584)  (1/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No  (1/2) N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (1/2) N/A
Parathyroid gland 2 No  (1/2) N/A
Parotid gland 2 No  (1/2) N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/2) N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/2) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (1/2) N/A
Stomach 2 No  (12/584)  (1/2) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No  (1/2) N/A
Submandibular gland 2 No  (2/132)  (1/2) N/A
Testis 2 No  (2/584) N/A
Thymus 2 No  (1/2) N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127)  (1/2) N/A
Trachea 2 No  (1/2) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No  (1/2) N/A
Uterus 2 No  (1/2) N/A
Vagina 2 No  (1/2) N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 8  (1/47)  (8/8) N/A
Axial skeleton 8  (1/51)  (8/8) N/A
Brain 8  (6/485) N/A
Central nervous system ganglion 8  (1/51)  (2/8) N/A
Dorsal root ganglion 8  (1/47) N/A
Ear 8  (1/485) N/A
Embryo 8  (1/485)  (8/8) N/A
Outer ear 8  (1/47) N/A
Eye 8  (1/485)  (7/8) N/A
Femur pre-cartilage condensation 5  (1/46)  (3/5) N/A
Foot 8  (1/485) N/A
Forearm 8  (1/282)  (7/8) N/A
Forebrain 8  (1/485) N/A
Forelimb 8  (1/485)  (7/8) N/A
Fronto-nasal process 8  (1/48)  (5/8) N/A
Gut 7  (1/50)  (5/7) N/A
Hand 8  (1/485) N/A
Head 8  (5/485)  (6/8) N/A
Head mesenchyme 8  (1/47)  (6/8) N/A
Heart 8  (1/485)  (8/8) N/A
Heart ventricle 8  (1/47)  (6/8) N/A
Hindbrain 8  (6/485) N/A
Hindlimb 8  (1/485)  (5/8) N/A
Humerus pre-cartilage condensation 5  (1/46)  (3/5) N/A
Inner ear 5  (1/46) N/A
Intestine 8  (1/47)  (6/8) N/A
Liver 8  (1/485) N/A
Lower leg 8  (1/282)  (2/8) N/A
Lung 8  (1/485)  (1/8) N/A
Mandibular process 8  (1/485)  (5/8) N/A
Maxillary process 8  (1/485)  (5/8) N/A
Meckel's cartilage 8  (5/8) N/A
Midbrain 8  (1/485) N/A
Nasal septum 8  (1/47) N/A
Nose 8  (1/51)  (5/8) N/A
Notochord 8  (1/47)  (3/8) N/A
Oral cavity 8  (1/485)  (5/8) N/A
Outflow tract 8  (1/47)  (8/8) N/A
8  (7/25) N/A
Radius-ulna pre-cartilage condensation 8  (1/46)  (7/8) N/A
Rib pre-cartilage condensation 2  (1/46) N/A
Skeleton 8  (1/51) N/A
Skin 8  (1/485) N/A
Spinal cord 8  (1/50) N/A
Tail 8  (1/485)  (1/8) N/A
Tail somite 8  (1/485)  (3/8) N/A
Thoracic vertebral cartilage condensation 3  (1/46) N/A
Tongue 5  (1/46) N/A
Trunk mesenchyme 8  (1/47)  (5/8) N/A
Umbilical artery embryonic part 8  (1/47)  (7/8) N/A
Umbilical vein embryonic part 8  (1/47)  (7/8) N/A
Upper arm 8  (1/282)  (5/8) N/A
Upper leg 8  (1/282)  (5/8) N/A
Vibrissa 8  (1/47) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
20 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Slc25a3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Slc25a3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc25a3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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