Genes Phenotypes

Gene: Slc25a1

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Name
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
MGI ID
MGI:1345283
Synonyms
Dgsj Slc20a3 1300019P08Rik 2610100G11Rik
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (23) Measurements chart (310) All data table (1337)
Expression & images (113) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased blood urea nitrogen level Slc25a1em1(IMPC)KMPC HET Early adult 1.32×10-06
abnormal skin coloration Slc25a1em1(IMPC)KMPC HET E18.5 0.00
abnormal placenta size Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal limb morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal ear morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal forebrain morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal embryo size Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal embryo size Slc25a1em1(IMPC)KMPC HOM E18.5 0.00
abnormal eye anterior chamber depth Slc25a1tm1b(EUCOMM)Wtsi HET Early adult 1.15×10-06
preweaning lethality, complete penetrance Slc25a1em1(IMPC)KMPC HOM Early adult 0.00
abnormal hindbrain morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal head shape Slc25a1em1(IMPC)KMPC HOM E18.5 0.00
abnormal cranium morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal head size Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal embryo size Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal head shape Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
pallor Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal tail morphology Slc25a1em1(IMPC)KMPC HOM E12.5 0.00
abnormal facial morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal tail morphology Slc25a1tm1b(EUCOMM)Wtsi HET E18.5 0.00
abnormal neural tube closure Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
preweaning lethality, complete penetrance Slc25a1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal craniofacial morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Bone 2 No  Wholemount images
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  Wholemount images
Cecum 1 No  (12/377) N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (2)
Cartilage tissue ambiguous
Cartilage tissue ambiguous
Bone ambiguous
Bone ambiguous
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/61) N/A
Axial skeleton 2  (1/65) N/A
Brain 2  (6/506) N/A
Central nervous system ganglion 2  (1/74) N/A
Cranium 2  (1/65) N/A
Dorsal root ganglion 2  (1/61) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507) N/A
Outer ear 2  (1/72) N/A
Eye 2  (1/506) N/A
Femur pre-cartilage condensation 2  (1/56) N/A
Foot 2  (1/506) N/A
Forearm 2  (1/303) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Fronto-nasal process 2  (1/62) N/A
Gut 2  (1/60) N/A
Hand 2  (1/506) N/A
Head 2  (5/506) N/A
Head mesenchyme 2  (1/61) N/A
Heart 2  (1/506) N/A
Heart ventricle 2  (1/61) N/A
Hindbrain 2  (6/506) N/A
Hindlimb 2  (1/506) N/A
Humerus pre-cartilage condensation 2  (1/65) N/A
Inner ear 2  (1/65) N/A
Intestine 2  (1/59) N/A
Liver 2  (1/504) N/A
Lower leg 2  (1/303) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Mesonephros of female 2  (1/56) N/A
Mesonephros of male 2  (1/56) N/A
Metanephros 2  (1/56) N/A
Midbrain 2  (1/506) N/A
Nasal septum 2  (1/61) N/A
Nose 2  (1/76) N/A
Notochord 2  (1/61) N/A
Oral cavity 2  (1/504) N/A
Outflow tract 2  (1/61) N/A
Pancreas 2  (1/56) N/A
Pericardium 2  (1/56) N/A
Pharynx 2  (1/57) N/A
Radius-ulna pre-cartilage condensation 2  (1/65) N/A
Rib pre-cartilage condensation 2  (1/58) N/A
Skeleton 2  (1/76) N/A
Skin 2  (1/506) N/A
Spinal cord 2  (1/73) N/A
Stomach 2  (1/56) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A
Thoracic vertebral cartilage condensation 2  (1/56) N/A
Tongue 2  (1/56) N/A
Trachea 2  (1/60) N/A
Trunk mesenchyme 2  (1/61) N/A
Umbilical artery embryonic part 2  (1/61) N/A
Umbilical vein embryonic part 2  (1/61) N/A
Upper arm 2  (1/303) N/A
Upper leg 2  (1/303) N/A
Urinary system 2  (1/60) N/A
Vibrissa 2  (1/72) N/A

 Associated Images

X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
Eye Morphology: VIP of left eye
16 Images
Eye Morphology: VIP of right eye
16 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: VIP of right fundus
16 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Eye Morphology: Images Slit Lamp
1 Images
Embryo LacZ: LacZ images wholemount
4 Images

 Disease Models

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MGI Allele Allele Type Produced
Slc25a1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Slc25a1tm45102(L1L2_gt1) Targeting vectors
Slc25a1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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