Genes Phenotypes

Gene: Slc25a1

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Name
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
MGI ID
MGI:1345283
Synonyms
2610100G11Rik Dgsj 1300019P08Rik Slc20a3
Viability
Homozygous - Lethal
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (29) Measurements chart (245) All data table (1226)
Expression & images (113) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube closure Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
facial cleft Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
increased bone mineral density Slc25a1tm1b(EUCOMM)Wtsi HET Early adult 2.87×10-05
preweaning lethality, complete penetrance Slc25a1tm1b(EUCOMM)Wtsi HOM Early adult 0.00
embryonic growth retardation Slc25a1em1(IMPC)KMPC HOM E18.5 0.00
exencephaly Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal cranium morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal embryo development Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal head shape Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
pallor Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal embryo development Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal tail morphology Slc25a1tm1b(EUCOMM)Wtsi HET E18.5 0.00
abnormal hindbrain morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
protruding tongue Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal tail morphology Slc25a1em1(IMPC)KMPC HOM E12.5 0.00
embryonic growth retardation Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal facial morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal facial morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal embryo size Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal forebrain morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal embryo size Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
preweaning lethality, complete penetrance Slc25a1em1(IMPC)KMPC HOM Early adult 0.00
abnormal craniofacial morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
edema Slc25a1em1(IMPC)KMPC HOM E15.5 0.00
abnormal head size Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal ear morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal embryo size Slc25a1em1(IMPC)KMPC HOM E18.5 0.00
abnormal limb morphology Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00
anophthalmia Slc25a1tm1b(EUCOMM)Wtsi HOM E18.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 2  (1/57) N/A
Axial skeleton 2  (1/61) N/A
Brain 2  (6/504) N/A
Central nervous system ganglion 2  (1/70) N/A
Cranium 2  (1/61) N/A
Dorsal root ganglion 2  (1/57) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505) N/A
Outer ear 2  (1/66) N/A
Eye 2  (1/504) N/A
Femur pre-cartilage condensation 2  (1/52) N/A
Foot 2  (1/504) N/A
Forearm 2  (1/297) N/A
Forebrain 2  (1/504) N/A
Forelimb 2  (1/504) N/A
Fronto-nasal process 2  (1/58) N/A
Gut 2  (1/56) N/A
Hand 2  (1/503) N/A
Head 2  (5/504) N/A
Head mesenchyme 2  (1/57) N/A
Heart 2  (1/504) N/A
Heart ventricle 2  (1/57) N/A
Hindbrain 2  (6/504) N/A
Hindlimb 2  (1/503) N/A
Humerus pre-cartilage condensation 2  (1/61) N/A
Inner ear 2  (1/61) N/A
Intestine 2  (1/55) N/A
Liver 2  (1/504) N/A
Lower leg 2  (1/297) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Mesonephros of female 2  (1/52) N/A
Mesonephros of male 2  (1/52) N/A
Metanephros 2  (1/52) N/A
Midbrain 2  (1/504) N/A
Nasal septum 2  (1/57) N/A
Nose 2  (1/70) N/A
Notochord 2  (1/57) N/A
Oral cavity 2  (1/504) N/A
Outflow tract 2  (1/57) N/A
Pancreas 2  (1/52) N/A
Pericardium 2  (1/52) N/A
Pharynx 2  (1/52) N/A
Radius-ulna pre-cartilage condensation 2  (1/61) N/A
Rib pre-cartilage condensation 2  (1/54) N/A
Skeleton 2  (1/70) N/A
Skin 2  (1/504) N/A
Spinal cord 2  (1/69) N/A
Stomach 2  (1/52) N/A
Tail 2  (1/504) N/A
Tail somite 2  (1/504) N/A
Thoracic vertebral cartilage condensation 2  (1/52) N/A
Tongue 2  (1/52) N/A
Trachea 2  (1/56) N/A
Trunk mesenchyme 2  (1/57) N/A
Umbilical artery embryonic part 2  (1/57) N/A
Umbilical vein embryonic part 2  (1/57) N/A
Upper arm 2  (1/297) N/A
Upper leg 2  (1/297) N/A
Urinary system 2  (1/56) N/A
Vibrissa 2  (1/66) N/A

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Eye Morphology: Images Ophthalmoscopy
3 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

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MGI Allele Allele Type Produced
Slc25a1tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Slc25a1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc25a1tm45102(L1L2_gt1) Targeting vectors

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