Gene: Slc6a2

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Name
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
MGI ID
MGI:1270850
Synonyms
Slc6a5 NE transporter NET norepinephrine transporter
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal gait Slc6a2tm1b(EUCOMM)Hmgu HOM Early adult 9.19×10-07
impaired glucose tolerance Slc6a2tm1b(EUCOMM)Hmgu HET Early adult 1.12×10-06
preweaning lethality, incomplete penetrance Slc6a2tm1b(EUCOMM)Hmgu HOM   Early adult 0.00
small heart Slc6a2tm1b(EUCOMM)Hmgu HOM Early adult 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584) N/A
Aorta 2 No  (1/584) N/A
Bone 2 No N/A
Brain 2 No  (4/584) N/A
Brainstem 2 No  (2/584) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/584) N/A
Cerebellum 2 No  (3/584) N/A
Cerebral cortex 2 No  (2/584) N/A
Esophagus 2 No  (7/408) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/584) N/A
Hippocampus 2 No  (3/584) N/A
Hypothalamus 2 No  (2/584) N/A
Kidney 2 No  (21/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/584) N/A
Lung 2 No  (2/584) N/A
Lymph node 2 No  (1/584) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/584) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (1/562) N/A
Peripheral nervous system 2 No  (2/584) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/584) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/584) N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (3/584) N/A
Spleen 2 No  (3/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (3/584) N/A
Testis 2 No  (6/584)  (1/2)  Wholemount images
Thymus 2 No  (1/584) N/A
Thyroid gland 2 No  (16/584) N/A
Trachea 2 No  (3/584) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 1  (6/507) Image Only N/A
Ear 1  (1/507) Image Only N/A
Embryo 1  (1/508) Image Only N/A
Eye 1  (1/507) Image Only N/A
Footplate 1  (1/507) Image Only N/A
Forebrain 1  (1/507) Image Only N/A
Forelimb 1  (1/507) Image Only N/A
Handplate 1  (1/507) Image Only N/A
Head 1  (5/507) Image Only N/A
Heart 1  (1/507) Image Only N/A
Hindbrain 1  (6/507) Image Only N/A
Hindlimb 1  (1/507) Image Only N/A
Liver 1  (1/502) Image Only N/A
Lung 1  (1/502) Image Only N/A
Mandibular process 1  (1/507) Image Only N/A
Maxillary process 1  (1/507) Image Only N/A
Midbrain 1  (1/507) Image Only N/A
Oral cavity 1  (1/502) Image Only N/A
Skin 1  (1/507) Image Only N/A
Tail 1  (1/507) Image Only N/A
Tail somite group 1  (1/507) Image Only N/A

 Associated Images

X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images
Echo: M-Mode Images
44 Images
X-ray: XRay Images Whole Body Lateral Orientation
17 Images
X-ray: XRay Images Whole Body Dorso Ventral
17 Images
Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Skull Lateral Orientation
2 Images
Adult LacZ: LacZ Images Wholemount
1 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
3 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Slc6a2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Slc6a2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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