Gene: Septin5

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
cardiovascular system phenotype Septin5tm1b(EUCOMM)Hmgu HET Early adult 6.61×10-07
improved glucose tolerance Septin5tm1b(EUCOMM)Hmgu HET Early adult 1.98×10-05
thrombocytopenia Septin5tm1b(EUCOMM)Hmgu HET Early adult 5.20×10-08
small spleen Septin5tm1b(EUCOMM)Hmgu HET Early adult 0.00
abnormal behavior Septin5tm1b(EUCOMM)Hmgu HET Early adult 8.04×10-05
short tibia Septin5tm1b(EUCOMM)Hmgu HET Early adult 1.91×10-07
preweaning lethality, incomplete penetrance Septin5tm1b(EUCOMM)Hmgu HOM Early adult 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  Wholemount images
Aorta 4 No  (4/4)  Wholemount images
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No  (4/4) N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4) N/A
Cecum 4 No  (12/379)  (4/4)  Wholemount images
Cerebellum 4 No  (4/4) N/A
Cerebral cortex 4 No  (4/4) N/A
Chest bone 4 No  (4/4)  Wholemount images
Colon 4 No  (12/127)  (4/4) N/A
Cranium 4 No N/A
Diaphragm 4 No N/A
Duodenum 4 No  (2/127)  (4/4)  Wholemount images
Epididymis 4 No  (18/134)  Wholemount images
Esophagus 4 No  (7/415)  (4/4)  Wholemount images
Eye 4 No  (4/4)  Wholemount images
Gall bladder 4 No  Wholemount images
Gonadal fat pad 4 No N/A
Harderian gland 4 No  Wholemount images
Heart 4 No  (4/4)  Wholemount images
Hindlimb 4 No  (4/4)  Wholemount images
Hippocampus 4 No  (4/4) N/A
Hypothalamus 4 No  (4/4) N/A
Ileum 4 No  (14/127)  (4/4)  Wholemount images
Jejunum 4 No  (6/127)  (4/4)  Wholemount images
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (4/4) N/A
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No N/A
Main olfactory bulb 4 No  (4/4)  Wholemount images
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No  Wholemount images
Mesenteric lymph node 4 No  Wholemount images
Midbrain 4 No  (4/4) N/A
Olfactory lobe 4 No  (4/4) N/A
Oral epithelium 4 No  (4/4)  Wholemount images
Ovary 4 No  (1/584)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No  (4/4)  Wholemount images
Parotid gland 4 No  Wholemount images
Penis 4 No  (2/4)  Wholemount images
Peripheral nervous system 4 No  (4/4) N/A
Peyer's patch 4 No  (3/4)  Wholemount images
Pituitary gland 4 No  (4/4)  Wholemount images
Prostate gland 4 No  (12/584)  Wholemount images
Quadriceps 4 No N/A
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 No  (4/4)  Wholemount images
Small intestine 4 No  (9/584)  (4/4) N/A
Spinal cord 4 No  (4/4)  Wholemount images
Spleen 4 No  (2/584)  Wholemount images
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Stomach pyloric region 4 No N/A
Striatum 4 No  (4/4) N/A
Sublingual gland 4 No  Wholemount images
Submandibular gland 4 No  (2/132)  Wholemount images
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thalamus 4 No  (4/4) N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584)  Wholemount images
Tongue 4 No  (5/127)  (4/4)  Wholemount images
Trachea 4 No  (4/4)  Wholemount images
Trigeminal V nerve 4 No  (4/4)  Wholemount images
Urinary bladder 4 No  (4/4)  Wholemount images
Uterus 4 No  Wholemount images
Vagina 4 No  (2/4)  Wholemount images
Vas deferens 4 No  (15/388) N/A
Vascular system 4 No  (4/4) N/A
Vesicular gland 4 No  Wholemount images
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 13  (6/504)  (14/14) N/A
Ear 13  (1/504)  Wholemount images
Embryo 13  (1/505)  (14/14)  Wholemount images
Eye 13  (1/504)  (8/14)  Wholemount images
Foot 13  (1/504) N/A
Forearm 13  (1/297)  (14/14) N/A
Forebrain 13  (1/504)  (7/14) N/A
Forelimb 13  (1/504)  (14/14)  Wholemount images
Hand 13  (1/503) N/A
Head 13  (5/504)  (14/14)  Wholemount images
Heart 13  (1/504) N/A
Hindbrain 13  (6/504)  (14/14)  Wholemount images
Hindlimb 13  (1/503)  (8/14)  Wholemount images
Liver 13  (1/504) N/A
Lower leg 13  (1/297)  (8/14) N/A
Lung 13  (1/500) N/A
Mandibular process 13  (1/504)  Wholemount images
Maxillary process 13  (1/504)  Wholemount images
Midbrain 13  (1/504)  (1/14) N/A
Oral cavity 13  (1/504) N/A
Skin 13  (1/504) N/A
Tail 13  (1/504)  Wholemount images
Tail somite 13  (1/504) N/A
Upper arm 13  (1/297)  (11/14) N/A
Upper leg 13  (1/297)  (7/14) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
175 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Embryo LacZ: LacZ images wholemount
196 Images
Gross Pathology and Tissue Collection
4 Images
Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Septin5tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Septin5tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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