Gene: Med1

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Name
mediator complex subunit 1
MGI ID
MGI:1100846
Synonyms
TRAP 220 TRAP220 CRSP210 DRIP205 Pparbp l11Jus15 PBP
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hydrometra Med1tm3b(EUCOMM)Wtsi HET Early adult 0.00
abnormal eye morphology Med1tm3b(EUCOMM)Wtsi HOM E12.5 0.00
preweaning lethality, complete penetrance Med1tm3b(EUCOMM)Wtsi HOM   Early adult 0.00
abnormal heart morphology Med1tm3b(EUCOMM)Wtsi HET Early adult 0.00
pallor Med1tm3b(EUCOMM)Wtsi HOM E12.5 0.00
embryonic lethality prior to tooth bud stage Med1tm3b(EUCOMM)Wtsi HOM   E12.5 0.00
abnormal eye morphology Med1tm3b(EUCOMM)Wtsi HET Early adult 0.00
small superior vagus ganglion Med1tm3b(EUCOMM)Wtsi HET Early adult 0.00
abnormal embryo size Med1tm3b(EUCOMM)Wtsi HOM E12.5 0.00
enlarged uterus Med1tm3b(EUCOMM)Wtsi HET Early adult 0.00
pale yolk sac Med1tm3b(EUCOMM)Wtsi HOM E12.5 0.00
abnormal placenta size Med1tm3b(EUCOMM)Wtsi HOM E12.5 0.00
enlarged heart Med1tm3b(EUCOMM)Wtsi HET Early adult 0.00

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No N/A
2 No  (4/584) N/A
2 No  (2/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (11/370) N/A
2 No  (3/584) N/A
2 No  (2/584) N/A
2 No N/A
2 No  (11/126) N/A
2 No N/A
2 No  (1/126) N/A
2 No  (17/133)  (1/2)  Section images
2 No  (7/408) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No N/A
2 No  (3/584) N/A
2 No  (2/584) N/A
2 No  (13/126) N/A
2 No  (5/126) N/A
2 No  (21/584)  (2/2)  Section images
2 No  (10/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No  (1/584) N/A
2 No N/A
2 No  (5/584) N/A
2 No  (1/562) N/A
2 No N/A
2 No N/A
2 No  (2/584) N/A
2 No N/A
2 No  (1/584) N/A
2 No  (12/584) N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (1/584) N/A
2 No  (9/584) N/A
2 No  (3/584) N/A
2 No  (3/584) N/A
2 No  (12/584) N/A
2 No N/A
2 No  (3/584) N/A
2 No N/A
2 No  (2/131) N/A
2 No  (6/584)  (1/2)  Section images
2 No  (1/584) N/A
2 No  (16/584) N/A
2 No  (5/126) N/A
2 No  (3/584) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No  (14/381)  (1/2)  Section images
2 No N/A
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/63) N/A
Brain 2  (6/507) N/A
Central nervous system ganglion 2  (1/72) N/A
Ear 2  (1/507) N/A
Embryo 2  (1/508) Image Only N/A
Eye 2  (1/507) N/A
Footplate 2  (1/507) N/A
Forebrain 2  (1/507) N/A
Forelimb 2  (1/507) N/A
Gut 2  (1/58) N/A
Handplate 2  (1/507) N/A
Head 2  (5/507) N/A
Heart 2  (1/507)  (2/2) N/A
Hindbrain 2  (6/507) N/A
Hindlimb 2  (1/507) N/A
Liver 2  (1/502) N/A
Lung 2  (1/502) N/A
Mandibular process 2  (1/507) N/A
Maxillary process 2  (1/507) N/A
Midbrain 2  (1/507) N/A
Nose 2  (1/77) N/A
Oral cavity 2  (1/502) N/A
Skeleton 2  (1/77) N/A
Skin 2  (1/507) N/A
Spinal cord 2  (1/71) N/A
Tail 2  (1/507) N/A
Tail somite group 2  (1/507) N/A
Trachea 2  (1/58) N/A
Urinary system 2  (1/58) N/A

 Associated Images

Embryo LacZ: LacZ images wholemount
8 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Adult LacZ: LacZ Images Section
11 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Med1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Med1tm3a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Med1tm3b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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