Cxcr4 | C-X-C motif chemokine receptor 4
Physiological systems
22 / 24 physiological systems tested
13 Significantly impacted by the knock-out
Vision/eye Mortality/aging Reproductive system Integument Limbs/digits/tail Immune system Homeostasis/metabolism Embryo Hematopoietic system Endocrine/exocrine gland Renal/urinary system Cardiovascular system Growth/size/body region
9 No significant impact
2 Not tested
Data collections
Gene metrics:21Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
Human diseases caused by Cxcr4 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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